BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

225 related articles for article (PubMed ID: 27502960)

  • 1. Cell-permeable succinate prodrugs bypass mitochondrial complex I deficiency.
    Ehinger JK; Piel S; Ford R; Karlsson M; Sjövall F; Frostner EÅ; Morota S; Taylor RW; Turnbull DM; Cornell C; Moss SJ; Metzsch C; Hansson MJ; Fliri H; Elmér E
    Nat Commun; 2016 Aug; 7():12317. PubMed ID: 27502960
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Mitochondrial respiratory chain complex I dysfunction induced by N-methyl carbamate ex vivo can be alleviated with a cell-permeable succinate prodrug.
    Janowska JI; Piel S; Saliba N; Kim CD; Jang DH; Karlsson M; Kilbaugh TJ; Ehinger JK
    Toxicol In Vitro; 2020 Jun; 65():104794. PubMed ID: 32057835
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Cell-Permeable Succinate Increases Mitochondrial Membrane Potential and Glycolysis in Leigh Syndrome Patient Fibroblasts.
    Bakare AB; Rao RR; Iyer S
    Cells; 2021 Aug; 10(9):. PubMed ID: 34571904
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Cell-permeable succinate prodrugs rescue mitochondrial respiration in cellular models of acute acetaminophen overdose.
    Piel S; Chamkha I; Dehlin AK; Ehinger JK; Sjövall F; Elmér E; Hansson MJ
    PLoS One; 2020; 15(4):e0231173. PubMed ID: 32251487
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Cell-Permeable Succinate Rescues Mitochondrial Respiration in Cellular Models of Amiodarone Toxicity.
    Bețiu AM; Chamkha I; Gustafsson E; Meijer E; Avram VF; Åsander Frostner E; Ehinger JK; Petrescu L; Muntean DM; Elmér E
    Int J Mol Sci; 2021 Oct; 22(21):. PubMed ID: 34769217
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Rescue from galactose-induced death of Leigh Syndrome patient cells by pyruvate and NAD
    Iannetti EF; Smeitink JAM; Willems PHGM; Beyrath J; Koopman WJH
    Cell Death Dis; 2018 Nov; 9(11):1135. PubMed ID: 30429455
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Succinate prodrugs as treatment for acute metabolic crisis during fluoroacetate intoxication in the rat.
    Piel S; Janowska JI; Ward JL; McManus MJ; Aronowitz DI; Janowski PK; Starr J; Hook JN; Hefti MM; Clayman CL; Elmér E; Hansson MJ; Jang DH; Karlsson M; Ehinger JK; Kilbaugh TJ
    Mol Cell Biochem; 2023 Jun; 478(6):1231-1244. PubMed ID: 36282352
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Reactive oxygen species are generated by the respiratory complex II--evidence for lack of contribution of the reverse electron flow in complex I.
    Moreno-Sánchez R; Hernández-Esquivel L; Rivero-Segura NA; Marín-Hernández A; Neuzil J; Ralph SJ; Rodríguez-Enríquez S
    FEBS J; 2013 Feb; 280(3):927-38. PubMed ID: 23206332
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Investigation of mitochondrial dysfunction by sequential microplate-based respiration measurements from intact and permeabilized neurons.
    Clerc P; Polster BM
    PLoS One; 2012; 7(4):e34465. PubMed ID: 22496810
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Ex vivo use of cell-permeable succinate prodrug attenuates mitochondrial dysfunction in blood cells obtained from carbon monoxide-poisoned individuals.
    Owiredu S; Ranganathan A; Eckmann DM; Shofer FS; Hardy K; Lambert DS; Kelly M; Jang DH
    Am J Physiol Cell Physiol; 2020 Jul; 319(1):C129-C135. PubMed ID: 32374677
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Deficiency of the complex I of the mitochondrial respiratory chain but improved adenylate control over succinate-dependent respiration are human gastric cancer-specific phenomena.
    Puurand M; Peet N; Piirsoo A; Peetsalu M; Soplepmann J; Sirotkina M; Peetsalu A; Hemminki A; Seppet E
    Mol Cell Biochem; 2012 Nov; 370(1-2):69-78. PubMed ID: 22821176
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Isoflurane modulates cardiac mitochondrial bioenergetics by selectively attenuating respiratory complexes.
    Agarwal B; Dash RK; Stowe DF; Bosnjak ZJ; Camara AK
    Biochim Biophys Acta; 2014 Mar; 1837(3):354-65. PubMed ID: 24355434
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Pathogenic Bi-allelic Mutations in NDUFAF8 Cause Leigh Syndrome with an Isolated Complex I Deficiency.
    Alston CL; Veling MT; Heidler J; Taylor LS; Alaimo JT; Sung AY; He L; Hopton S; Broomfield A; Pavaine J; Diaz J; Leon E; Wolf P; McFarland R; Prokisch H; Wortmann SB; Bonnen PE; Wittig I; Pagliarini DJ; Taylor RW
    Am J Hum Genet; 2020 Jan; 106(1):92-101. PubMed ID: 31866046
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Multisystem mitochondrial diseases due to mutations in mtDNA-encoded subunits of complex I.
    Danhelovska T; Kolarova H; Zeman J; Hansikova H; Vaneckova M; Lambert L; Kucerova-Vidrova V; Berankova K; Honzik T; Tesarova M
    BMC Pediatr; 2020 Jan; 20(1):41. PubMed ID: 31996177
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Cell-Permeable Succinate Rescues Mitochondrial Respiration in Cellular Models of Statin Toxicity.
    Avram VF; Chamkha I; Åsander-Frostner E; Ehinger JK; Timar RZ; Hansson MJ; Muntean DM; Elmér E
    Int J Mol Sci; 2021 Jan; 22(1):. PubMed ID: 33401621
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Succinate ameliorates energy deficits and prevents dysfunction of complex I in injured renal proximal tubular cells.
    Nowak G; Clifton GL; Bakajsova D
    J Pharmacol Exp Ther; 2008 Mar; 324(3):1155-62. PubMed ID: 18055880
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Effects of isoflurane on complex II‑associated mitochondrial respiration and reactive oxygen species production: Roles of nitric oxide and mitochondrial KATP channels.
    Wang J; Sun J; Qiao S; Li H; Che T; Wang C; An J
    Mol Med Rep; 2019 Nov; 20(5):4383-4390. PubMed ID: 31545457
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Leigh syndrome associated with mitochondrial complex I deficiency due to novel mutations In NDUFV1 and NDUFS2.
    Marin SE; Mesterman R; Robinson B; Rodenburg RJ; Smeitink J; Tarnopolsky MA
    Gene; 2013 Mar; 516(1):162-7. PubMed ID: 23266820
    [TBL] [Abstract][Full Text] [Related]  

  • 19. NDUFB8 Mutations Cause Mitochondrial Complex I Deficiency in Individuals with Leigh-like Encephalomyopathy.
    Piekutowska-Abramczuk D; Assouline Z; Mataković L; Feichtinger RG; Koňařiková E; Jurkiewicz E; Stawiński P; Gusic M; Koller A; Pollak A; Gasperowicz P; Trubicka J; Ciara E; Iwanicka-Pronicka K; Rokicki D; Hanein S; Wortmann SB; Sperl W; Rötig A; Prokisch H; Pronicka E; Płoski R; Barcia G; Mayr JA
    Am J Hum Genet; 2018 Mar; 102(3):460-467. PubMed ID: 29429571
    [TBL] [Abstract][Full Text] [Related]  

  • 20. A constant and similar assembly defect of mitochondrial respiratory chain complex I allows rapid identification of NDUFS4 mutations in patients with Leigh syndrome.
    Assouline Z; Jambou M; Rio M; Bole-Feysot C; de Lonlay P; Barnerias C; Desguerre I; Bonnemains C; Guillermet C; Steffann J; Munnich A; Bonnefont JP; Rötig A; Lebre AS
    Biochim Biophys Acta; 2012 Jun; 1822(6):1062-9. PubMed ID: 22326555
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 12.