BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

331 related articles for article (PubMed ID: 27507813)

  • 1. Leucine Carboxyl Methyltransferase 1 (LCMT-1) Methylates Protein Phosphatase 4 (PP4) and Protein Phosphatase 6 (PP6) and Differentially Regulates the Stable Formation of Different PP4 Holoenzymes.
    Hwang J; Lee JA; Pallas DC
    J Biol Chem; 2016 Sep; 291(40):21008-21019. PubMed ID: 27507813
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Global loss of leucine carboxyl methyltransferase-1 causes severe defects in fetal liver hematopoiesis.
    Lee JA; Wang Z; Sambo D; Bunting KD; Pallas DC
    J Biol Chem; 2018 Jun; 293(25):9636-9650. PubMed ID: 29735529
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Regulation of PP2A, PP4, and PP6 holoenzyme assembly by carboxyl-terminal methylation.
    Lyons SP; Greiner EC; Cressey LE; Adamo ME; Kettenbach AN
    Sci Rep; 2021 Nov; 11(1):23031. PubMed ID: 34845248
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Leucine carboxyl methyltransferase-1 is necessary for normal progression through mitosis in mammalian cells.
    Lee JA; Pallas DC
    J Biol Chem; 2007 Oct; 282(42):30974-84. PubMed ID: 17724024
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Parallel purification of three catalytic subunits of the protein serine/threonine phosphatase 2A family (PP2A(C), PP4(C), and PP6(C)) and analysis of the interaction of PP2A(C) with alpha4 protein.
    Kloeker S; Reed R; McConnell JL; Chang D; Tran K; Westphal RS; Law BK; Colbran RJ; Kamoun M; Campbell KS; Wadzinski BE
    Protein Expr Purif; 2003 Sep; 31(1):19-33. PubMed ID: 12963337
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Folate deficiency induces in vitro and mouse brain region-specific downregulation of leucine carboxyl methyltransferase-1 and protein phosphatase 2A B(alpha) subunit expression that correlate with enhanced tau phosphorylation.
    Sontag JM; Nunbhakdi-Craig V; Montgomery L; Arning E; Bottiglieri T; Sontag E
    J Neurosci; 2008 Nov; 28(45):11477-87. PubMed ID: 18987184
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Effects of carboxyl-terminal methylation on holoenzyme function of the PP2A subfamily.
    Nasa I; Kettenbach AN
    Biochem Soc Trans; 2020 Oct; 48(5):2015-2027. PubMed ID: 33125487
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Mechanisms of the scaffold subunit in facilitating protein phosphatase 2A methylation.
    Stanevich V; Zheng A; Guo F; Jiang L; Wlodarchak N; Xing Y
    PLoS One; 2014; 9(1):e86955. PubMed ID: 24466300
    [TBL] [Abstract][Full Text] [Related]  

  • 9. The structural basis for tight control of PP2A methylation and function by LCMT-1.
    Stanevich V; Jiang L; Satyshur KA; Li Y; Jeffrey PD; Li Z; Menden P; Semmelhack MF; Xing Y
    Mol Cell; 2011 Feb; 41(3):331-42. PubMed ID: 21292165
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Purification and identification of a novel subunit of protein serine/threonine phosphatase 4.
    Kloeker S; Wadzinski BE
    J Biol Chem; 1999 Feb; 274(9):5339-47. PubMed ID: 10026142
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Carboxyl methylation regulates phosphoprotein phosphatase 2A by controlling the association of regulatory B subunits.
    Tolstykh T; Lee J; Vafai S; Stock JB
    EMBO J; 2000 Nov; 19(21):5682-91. PubMed ID: 11060019
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Circumventing cellular control of PP2A by methylation promotes transformation in an Akt-dependent manner.
    Jackson JB; Pallas DC
    Neoplasia; 2012 Jul; 14(7):585-99. PubMed ID: 22904676
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Methylation of the C-terminal leucine residue of the PP2A catalytic subunit is unnecessary for the catalytic activity and the binding of regulatory subunit (PR55/B).
    Ikehara T; Ikehara S; Imamura S; Shinjo F; Yasumoto T
    Biochem Biophys Res Commun; 2007 Mar; 354(4):1052-7. PubMed ID: 17274953
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Protein Phosphatase 2A and Its Methylation Modulating Enzymes LCMT-1 and PME-1 Are Dysregulated in Tauopathies of Progressive Supranuclear Palsy and Alzheimer Disease.
    Park HJ; Lee KW; Oh S; Yan R; Zhang J; Beach TG; Adler CH; Voronkov M; Braithwaite SP; Stock JB; Mouradian MM
    J Neuropathol Exp Neurol; 2018 Feb; 77(2):139-148. PubMed ID: 29281045
    [TBL] [Abstract][Full Text] [Related]  

  • 15. The biogenesis of active protein phosphatase 2A holoenzymes: a tightly regulated process creating phosphatase specificity.
    Sents W; Ivanova E; Lambrecht C; Haesen D; Janssens V
    FEBS J; 2013 Jan; 280(2):644-61. PubMed ID: 22443683
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Leucine Carboxyl Methyltransferase 1 Overexpression Protects Against Cognitive and Electrophysiological Impairments in Tg2576 APP Transgenic Mice.
    Gnanaprakash M; Staniszewski A; Zhang H; Pitstick R; Kavanaugh MP; Arancio O; Nicholls RE
    J Alzheimers Dis; 2021; 79(4):1813-1829. PubMed ID: 33459709
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Leucine Carboxyl Methyltransferase Downregulation and Protein Phosphatase Methylesterase Upregulation Contribute Toward the Inhibition of Protein Phosphatase 2A by α-Synuclein.
    Tian H; Lu Y; Liu J; Liu W; Lu L; Duan C; Gao G; Yang H
    Front Aging Neurosci; 2018; 10():173. PubMed ID: 29950985
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Reduced Expression of the PP2A Methylesterase, PME-1, or the PP2A Methyltransferase, LCMT-1, Alters Sensitivity to Beta-Amyloid-Induced Cognitive and Electrophysiological Impairments in Mice.
    Staniszewski A; Zhang H; Asam K; Pitstick R; Kavanaugh MP; Arancio O; Nicholls RE
    J Neurosci; 2020 Jun; 40(23):4596-4608. PubMed ID: 32341098
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Protein phosphatases PP2A, PP4 and PP6: mediators and regulators in development and responses to environmental cues.
    Lillo C; Kataya AR; Heidari B; Creighton MT; Nemie-Feyissa D; Ginbot Z; Jonassen EM
    Plant Cell Environ; 2014 Dec; 37(12):2631-48. PubMed ID: 24810976
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Cross talk between PI3K-AKT-GSK-3β and PP2A pathways determines tau hyperphosphorylation.
    Wang Y; Yang R; Gu J; Yin X; Jin N; Xie S; Wang Y; Chang H; Qian W; Shi J; Iqbal K; Gong CX; Cheng C; Liu F
    Neurobiol Aging; 2015 Jan; 36(1):188-200. PubMed ID: 25219467
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 17.