BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

137 related articles for article (PubMed ID: 27509024)

  • 1. Exercise Activates p53 and Negatively Regulates IGF-1 Pathway in Epidermis within a Skin Cancer Model.
    Yu M; King B; Ewert E; Su X; Mardiyati N; Zhao Z; Wang W
    PLoS One; 2016; 11(8):e0160939. PubMed ID: 27509024
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Ectodomain-specific E-cadherin antibody suppresses skin SCC growth and reduces tumor grade: a multitargeted therapy modulating RTKs and the PTEN-p53-MDM2 axis.
    Brouxhon SM; Kyrkanides S; Raja V; Silberfeld A; Teng X; Trochesset D; Cohen J; Ma L
    Mol Cancer Ther; 2014 Jul; 13(7):1791-802. PubMed ID: 24748654
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Unbalancing p53/Mdm2/IGF-1R axis by Mdm2 activation restrains the IGF-1-dependent invasive phenotype of skin melanoma.
    Worrall C; Suleymanova N; Crudden C; Trocoli Drakensjö I; Candrea E; Nedelcu D; Takahashi SI; Girnita L; Girnita A
    Oncogene; 2017 Jun; 36(23):3274-3286. PubMed ID: 28092675
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Influence of zinc deficiency on Akt-Mdm2-p53 and Akt-p21 signaling axes in normal and malignant human prostate cells.
    Han CT; Schoene NW; Lei KY
    Am J Physiol Cell Physiol; 2009 Nov; 297(5):C1188-99. PubMed ID: 19657064
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Ganglioside GM3 modulates tumor suppressor PTEN-mediated cell cycle progression--transcriptional induction of p21(WAF1) and p27(kip1) by inhibition of PI-3K/AKT pathway.
    Choi HJ; Chung TW; Kang SK; Lee YC; Ko JH; Kim JG; Kim CH
    Glycobiology; 2006 Jul; 16(7):573-83. PubMed ID: 16574813
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Impact of PTEN on the expression of insulin-like growth factors (IGFs) and IGF-binding proteins in human gastric adenocarcinoma cells.
    Yi HK; Kim SY; Hwang PH; Kim CY; Yang DH; Oh Y; Lee DY
    Biochem Biophys Res Commun; 2005 May; 330(3):760-7. PubMed ID: 15809062
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Fos cooperation with PTEN loss elicits keratoacanthoma not carcinoma, owing to p53/p21 WAF-induced differentiation triggered by GSK3beta inactivation and reduced AKT activity.
    Yao D; Alexander CL; Quinn JA; Chan WC; Wu H; Greenhalgh DA
    J Cell Sci; 2008 May; 121(Pt 10):1758-69. PubMed ID: 18445683
    [TBL] [Abstract][Full Text] [Related]  

  • 8. PTEN ablation in Ras(Ha)/Fos skin carcinogenesis invokes p53-dependent p21 to delay conversion while p53-independent p21 limits progression via cyclin D1/E2 inhibition.
    Macdonald FH; Yao D; Quinn JA; Greenhalgh DA
    Oncogene; 2014 Aug; 33(32):4132-43. PubMed ID: 24037529
    [TBL] [Abstract][Full Text] [Related]  

  • 9. The regulation of AMPK beta1, TSC2, and PTEN expression by p53: stress, cell and tissue specificity, and the role of these gene products in modulating the IGF-1-AKT-mTOR pathways.
    Feng Z; Hu W; de Stanchina E; Teresky AK; Jin S; Lowe S; Levine AJ
    Cancer Res; 2007 Apr; 67(7):3043-53. PubMed ID: 17409411
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Could changes in the regulation of the PI3K/PKB/Akt signaling pathway and cell cycle be involved in astrocytic tumor pathogenesis and progression?
    Hlobilkova A; Ehrmann J; Sedlakova E; Krejci V; Knizetova P; Fiuraskova M; Kala M; Kalita O; Kolar Z
    Neoplasma; 2007; 54(4):334-41. PubMed ID: 17822324
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Weight Loss via exercise with controlled dietary intake may affect phospholipid profile for cancer prevention in murine skin tissues.
    Ouyang P; Jiang Y; Doan HM; Xie L; Vasquez D; Welti R; Su X; Lu N; Herndon B; Yang SS; Jeannotte R; Wang W
    Cancer Prev Res (Phila); 2010 Apr; 3(4):466-77. PubMed ID: 20233900
    [TBL] [Abstract][Full Text] [Related]  

  • 12. [Expression and clinical significance of P53 pathway-associated proteins in pancreatic carcinoma].
    Yu GZ; Zhu MH; Chen Y; Ni CR; Li FM
    Ai Zheng; 2005 Nov; 24(11):1398-403. PubMed ID: 16552971
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Dietary energy restriction, in part through glucocorticoid hormones, mediates the impact of 12-O-tetradecanoylphorbol-13-acetate on jun D and fra-1 in Sencar mouse epidermis.
    Przybyszewski J; Wang W; Au A; Perry C; Guetzko M; Koehler K; Birt DF
    Mol Carcinog; 2010 Jun; 49(6):592-602. PubMed ID: 20232358
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Mdm2 plays a positive role as an effector of p53-dependent responses.
    Giono LE; Manfredi JJ
    Cell Cycle; 2007 Sep; 6(17):2143-7. PubMed ID: 17786043
    [TBL] [Abstract][Full Text] [Related]  

  • 15. MDM2 induces hyperplasia and premalignant lesions when expressed in the basal layer of the epidermis.
    Ganguli G; Abecassis J; Wasylyk B
    EMBO J; 2000 Oct; 19(19):5135-47. PubMed ID: 11013216
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Mdm2, p53, p21 and pAKT protein pathways in benign neoplasms of the salivary gland.
    Marques YM; de Lima Mde D; de Melo Alves Sde M; Soares FA; de Araújo VC; Pinto Ddos S; Mantesso A
    Oral Oncol; 2008 Sep; 44(9):903-8. PubMed ID: 18485798
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Role of PI3K/Akt signaling in insulin-like growth factor-1 (IGF-1) skin tumor promotion.
    Wilker E; Lu J; Rho O; Carbajal S; Beltrán L; DiGiovanni J
    Mol Carcinog; 2005 Oct; 44(2):137-45. PubMed ID: 16086373
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Silibinin prevents ultraviolet radiation-caused skin damages in SKH-1 hairless mice via a decrease in thymine dimer positive cells and an up-regulation of p53-p21/Cip1 in epidermis.
    Dhanalakshmi S; Mallikarjuna GU; Singh RP; Agarwal R
    Carcinogenesis; 2004 Aug; 25(8):1459-65. PubMed ID: 15033902
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Insulin-like growth factor-1 induces Mdm2 and down-regulates p53, attenuating the myocyte renin-angiotensin system and stretch-mediated apoptosis.
    Leri A; Liu Y; Claudio PP; Kajstura J; Wang X; Wang S; Kang P; Malhotra A; Anversa P
    Am J Pathol; 1999 Feb; 154(2):567-80. PubMed ID: 10027414
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Reduced signaling of PI3K-Akt and RAS-MAPK pathways is the key target for weight-loss-induced cancer prevention by dietary calorie restriction and/or physical activity.
    Standard J; Jiang Y; Yu M; Su X; Zhao Z; Xu J; Chen J; King B; Lu L; Tomich J; Baybutt R; Wang W
    J Nutr Biochem; 2014 Dec; 25(12):1317-23. PubMed ID: 25283328
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 7.