188 related articles for article (PubMed ID: 27512044)
1. Ultrapotent vinblastines in which added molecular complexity further disrupts the target tubulin dimer-dimer interface.
Carney DW; Lukesh JC; Brody DM; Brütsch MM; Boger DL
Proc Natl Acad Sci U S A; 2016 Aug; 113(35):9691-8. PubMed ID: 27512044
[TBL] [Abstract][Full Text] [Related]
2. Synthesis and biological evaluation of C-13' substituted 7'-homo-anhydrovinblastine derivatives.
Gherbovet O; La Spisa F; Thoret S; Alvarez MCG; Levaique H; Bignon J; Roussi F
Bioorg Med Chem Lett; 2015 Apr; 25(8):1771-1773. PubMed ID: 25804719
[TBL] [Abstract][Full Text] [Related]
3. Theoretical insight into the structural mechanism for the binding of vinblastine with tubulin.
Chi S; Xie W; Zhang J; Xu S
J Biomol Struct Dyn; 2015; 33(10):2234-54. PubMed ID: 25588192
[TBL] [Abstract][Full Text] [Related]
4. Total synthesis of vinblastine, related natural products, and key analogues and development of inspired methodology suitable for the systematic study of their structure-function properties.
Sears JE; Boger DL
Acc Chem Res; 2015 Mar; 48(3):653-62. PubMed ID: 25586069
[TBL] [Abstract][Full Text] [Related]
5. A remarkable series of vinblastine analogues displaying enhanced activity and an unprecedented tubulin binding steric tolerance: C20' urea derivatives.
Leggans EK; Duncan KK; Barker TJ; Schleicher KD; Boger DL
J Med Chem; 2013 Feb; 56(3):628-39. PubMed ID: 23244701
[TBL] [Abstract][Full Text] [Related]
6. Ultra-potent vinblastine analogues improve on-target activity of the parent microtubulin-targeting compound.
Radakovic A; Boger DL
Bioorg Med Chem Lett; 2019 Jun; 29(11):1370-1374. PubMed ID: 30952593
[TBL] [Abstract][Full Text] [Related]
7. Gatorbulin-1, a distinct cyclodepsipeptide chemotype, targets a seventh tubulin pharmacological site.
Matthew S; Chen QY; Ratnayake R; Fermaintt CS; Lucena-Agell D; Bonato F; Prota AE; Lim ST; Wang X; Díaz JF; Risinger AL; Paul VJ; Oliva MÁ; Luesch H
Proc Natl Acad Sci U S A; 2021 Mar; 118(9):. PubMed ID: 33619102
[TBL] [Abstract][Full Text] [Related]
8. Synthesis and biological evaluation of vinca alkaloids and phomopsin hybrids.
Ngo QA; Roussi F; Cormier A; Thoret S; Knossow M; Guénard D; Guéritte F
J Med Chem; 2009 Jan; 52(1):134-42. PubMed ID: 19072542
[TBL] [Abstract][Full Text] [Related]
9. Synthesis of a Potent Vinblastine: Rationally Designed Added Benign Complexity.
Allemann O; Brutsch M; Lukesh JC; Brody DM; Boger DL
J Am Chem Soc; 2016 Jul; 138(27):8376-9. PubMed ID: 27356080
[TBL] [Abstract][Full Text] [Related]
10. One-pot synthesis of vinca alkaloids-phomopsin hybrids.
Gherbovet O; Coderch C; García Alvarez MC; Bignon J; Thoret S; Guéritte F; Gago F; Roussi F
J Med Chem; 2014 Jun; 57(12):5470-6. PubMed ID: 24871162
[TBL] [Abstract][Full Text] [Related]
11. Key analogs of a uniquely potent synthetic vinblastine that contain modifications of the C20' ethyl substituent.
Allemann O; Cross RM; Brütsch MM; Radakovic A; Boger DL
Bioorg Med Chem Lett; 2017 Jul; 27(14):3055-3059. PubMed ID: 28551101
[TBL] [Abstract][Full Text] [Related]
12. Synthesis and biological evaluation of C-12' substituted vinflunine derivatives.
Lei XS; Yu XD; Yin L; Liu ZH; Tang PC
Bioorg Med Chem Lett; 2008 Aug; 18(16):4602-5. PubMed ID: 18653334
[TBL] [Abstract][Full Text] [Related]
13. Molecular docking and pharmacogenomics of vinca alkaloids and their monomeric precursors, vindoline and catharanthine.
Sertel S; Fu Y; Zu Y; Rebacz B; Konkimalla B; Plinkert PK; Krämer A; Gertsch J; Efferth T
Biochem Pharmacol; 2011 Mar; 81(6):723-35. PubMed ID: 21219884
[TBL] [Abstract][Full Text] [Related]
14. Total synthesis of vinblastine, vincristine, related natural products, and key structural analogues.
Ishikawa H; Colby DA; Seto S; Va P; Tam A; Kakei H; Rayl TJ; Hwang I; Boger DL
J Am Chem Soc; 2009 Apr; 131(13):4904-16. PubMed ID: 19292450
[TBL] [Abstract][Full Text] [Related]
15. [Thermodynamics of calmodulin and tubulin binding to the vinca-alkaloid vinorelbine].
Tsvetkov FO; Kulikova AA; Devred F; Zerniĭ EIu; Lafitte D; Makarov AA
Mol Biol (Mosk); 2011; 45(4):697-702. PubMed ID: 21954603
[TBL] [Abstract][Full Text] [Related]
16. Elaboration of simplified vinca alkaloids and phomopsin hybrids.
Ngo QA; Roussi F; Thoret S; Guéritte F
Chem Biol Drug Des; 2010 Mar; 75(3):284-94. PubMed ID: 20659111
[TBL] [Abstract][Full Text] [Related]
17. Synthesis and antiproliferativeactivity of new vinca alkaloids containing an α,β-unsaturated aromatic side chain.
Ngo QA; Nguyen le A; Vo NB; Nguyen TH; Roussi F; Nguyen TH; Nguyen VT
Bioorg Med Chem Lett; 2015 Dec; 25(23):5597-600. PubMed ID: 26522953
[TBL] [Abstract][Full Text] [Related]
18. Synthesis and SAR of vinca alkaloid analogues.
Voss ME; Ralph JM; Xie D; Manning DD; Chen X; Frank AJ; Leyhane AJ; Liu L; Stevens JM; Budde C; Surman MD; Friedrich T; Peace D; Scott IL; Wolf M; Johnson R
Bioorg Med Chem Lett; 2009 Feb; 19(4):1245-9. PubMed ID: 19147348
[TBL] [Abstract][Full Text] [Related]
19. Inhibitors of tubulin polymerization: synthesis and biological evaluation of hybrids of vindoline, anhydrovinblastine and vinorelbine with thiocolchicine, podophyllotoxin and baccatin III.
Passarella D; Giardini A; Peretto B; Fontana G; Sacchetti A; Silvani A; Ronchi C; Cappelletti G; Cartelli D; Borlak J; Danieli B
Bioorg Med Chem; 2008 Jun; 16(11):6269-85. PubMed ID: 18468444
[TBL] [Abstract][Full Text] [Related]
20. Synthesis and biological evaluation of a new series of highly functionalized 7'-homo-anhydrovinblastine derivatives.
Gherbovet O; Coderch C; García Alvarez MC; Bignon J; Thoret S; Martin MT; Guéritte F; Gago F; Roussi F
J Med Chem; 2013 Aug; 56(15):6088-100. PubMed ID: 23822556
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]