162 related articles for article (PubMed ID: 27516465)
1. Pharmacological Characterization of a Potent Inhibitor of Autotaxin in Animal Models of Inflammatory Bowel Disease and Multiple Sclerosis.
Thirunavukkarasu K; Tan B; Swearingen CA; Rocha G; Bui HH; McCann DJ; Jones SB; Norman BH; Pfeifer LA; Saha JK
J Pharmacol Exp Ther; 2016 Oct; 359(1):207-14. PubMed ID: 27516465
[TBL] [Abstract][Full Text] [Related]
2. A novel autotaxin inhibitor reduces lysophosphatidic acid levels in plasma and the site of inflammation.
Gierse J; Thorarensen A; Beltey K; Bradshaw-Pierce E; Cortes-Burgos L; Hall T; Johnston A; Murphy M; Nemirovskiy O; Ogawa S; Pegg L; Pelc M; Prinsen M; Schnute M; Wendling J; Wene S; Weinberg R; Wittwer A; Zweifel B; Masferrer J
J Pharmacol Exp Ther; 2010 Jul; 334(1):310-7. PubMed ID: 20392816
[TBL] [Abstract][Full Text] [Related]
3. Identification and pharmacological characterization of a novel inhibitor of autotaxin in rodent models of joint pain.
Thirunavukkarasu K; Swearingen CA; Oskins JL; Lin C; Bui HH; Jones SB; Pfeifer LA; Norman BH; Mitchell PG; Chambers MG
Osteoarthritis Cartilage; 2017 Jun; 25(6):935-942. PubMed ID: 27638130
[TBL] [Abstract][Full Text] [Related]
4. Selective Inhibition of Autotaxin Is Efficacious in Mouse Models of Liver Fibrosis.
Bain G; Shannon KE; Huang F; Darlington J; Goulet L; Prodanovich P; Ma GL; Santini AM; Stein AJ; Lonergan D; King CD; Calderon I; Lai A; Hutchinson JH; Evans JF
J Pharmacol Exp Ther; 2017 Jan; 360(1):1-13. PubMed ID: 27754931
[TBL] [Abstract][Full Text] [Related]
5. A novel highly potent autotaxin/ENPP2 inhibitor produces prolonged decreases in plasma lysophosphatidic acid formation in vivo and regulates urethral tension.
Saga H; Ohhata A; Hayashi A; Katoh M; Maeda T; Mizuno H; Takada Y; Komichi Y; Ota H; Matsumura N; Shibaya M; Sugiyama T; Nakade S; Kishikawa K
PLoS One; 2014; 9(4):e93230. PubMed ID: 24747415
[TBL] [Abstract][Full Text] [Related]
6. Increased autotaxin activity in multiple sclerosis.
Zahednasab H; Balood M; Harirchian MH; Mesbah-Namin SA; Rahimian N; Siroos B
J Neuroimmunol; 2014 Aug; 273(1-2):120-3. PubMed ID: 24984830
[TBL] [Abstract][Full Text] [Related]
7. Synthesis and Activity of a Novel Autotaxin Inhibitor-Icodextrin Conjugate.
Fisher N; Edwards MG; Hemming R; Allin SM; Wallis JD; Bulman Page PC; Mckenzie MJ; Jones SM; Elsegood MRJ; King-Underwood J; Richardson A
J Med Chem; 2018 Sep; 61(17):7942-7951. PubMed ID: 30059212
[TBL] [Abstract][Full Text] [Related]
8. Autotaxin is an inflammatory mediator and therapeutic target in thyroid cancer.
Benesch MG; Ko YM; Tang X; Dewald J; Lopez-Campistrous A; Zhao YY; Lai R; Curtis JM; Brindley DN; McMullen TP
Endocr Relat Cancer; 2015 Aug; 22(4):593-607. PubMed ID: 26037280
[TBL] [Abstract][Full Text] [Related]
9. Synthesis of novel 2-pyrrolidinone and pyrrolidine derivatives and study of their inhibitory activity against autotaxin enzyme.
Gerokonstantis DT; Nikolaou A; Magkrioti C; Afantitis A; Aidinis V; Kokotos G; Moutevelis-Minakakis P
Bioorg Med Chem; 2020 Jan; 28(2):115216. PubMed ID: 31864778
[TBL] [Abstract][Full Text] [Related]
10. Autotaxin, a secreted lysophospholipase D, as a promising therapeutic target in chronic inflammation and cancer.
Barbayianni E; Kaffe E; Aidinis V; Kokotos G
Prog Lipid Res; 2015 Apr; 58():76-96. PubMed ID: 25704398
[TBL] [Abstract][Full Text] [Related]
11. Anti-inflammatory and analgesic activities of SKLJI, a highly purified and injectable herbal extract of Lonicera japonica.
Ryu KH; Rhee HI; Kim JH; Yoo H; Lee BY; Um KA; Kim K; Noh JY; Lim KM; Chung JH
Biosci Biotechnol Biochem; 2010; 74(10):2022-8. PubMed ID: 20944425
[TBL] [Abstract][Full Text] [Related]
12. Anti-oxidant, anti-inflammatory, analgesic and antipyretic activities of grapevine leaf extract (Vitis vinifera) in mice and identification of its active constituents by LC-MS/MS analyses.
Aouey B; Samet AM; Fetoui H; Simmonds MSJ; Bouaziz M
Biomed Pharmacother; 2016 Dec; 84():1088-1098. PubMed ID: 27780137
[TBL] [Abstract][Full Text] [Related]
13. S32826, a nanomolar inhibitor of autotaxin: discovery, synthesis and applications as a pharmacological tool.
Ferry G; Moulharat N; Pradère JP; Desos P; Try A; Genton A; Giganti A; Beucher-Gaudin M; Lonchampt M; Bertrand M; Saulnier-Blache JS; Tucker GC; Cordi A; Boutin JA
J Pharmacol Exp Ther; 2008 Dec; 327(3):809-19. PubMed ID: 18755937
[TBL] [Abstract][Full Text] [Related]
14. Analgesic and Anti-Inflammatory Properties of Gelsolin in Acetic Acid Induced Writhing, Tail Immersion and Carrageenan Induced Paw Edema in Mice.
Gupta AK; Parasar D; Sagar A; Choudhary V; Chopra BS; Garg R; Ashish ; Khatri N
PLoS One; 2015; 10(9):e0135558. PubMed ID: 26426535
[TBL] [Abstract][Full Text] [Related]
15. Analgesic, anti-inflammatory and anti-platelet activities of Buddleja crispa.
Bukhari IA; Gilani AH; Meo SA; Saeed A
BMC Complement Altern Med; 2016 Feb; 16():79. PubMed ID: 26911873
[TBL] [Abstract][Full Text] [Related]
16. Anti-inflammatory, analgesic, and antioxidant activities of Pisonia aculeata: folk medicinal use to scientific approach.
Sen S; Chakraborty R; Rekha B; Revathi D; Ayyanna SC; Hemalatha G; Kumar Reddy GA; Hyndavi S; Ikhyatha Babu PJ; Prakash PR; Sridhar C
Pharm Biol; 2013 Apr; 51(4):426-32. PubMed ID: 23336600
[TBL] [Abstract][Full Text] [Related]
17. Autotaxin activity increases locally following lung injury, but is not required for pulmonary lysophosphatidic acid production or fibrosis.
Black KE; Berdyshev E; Bain G; Castelino FV; Shea BS; Probst CK; Fontaine BA; Bronova I; Goulet L; Lagares D; Ahluwalia N; Knipe RS; Natarajan V; Tager AM
FASEB J; 2016 Jun; 30(6):2435-50. PubMed ID: 27006447
[TBL] [Abstract][Full Text] [Related]
18. Autotaxin in the crosshairs: taking aim at cancer and other inflammatory conditions.
Benesch MG; Ko YM; McMullen TP; Brindley DN
FEBS Lett; 2014 Aug; 588(16):2712-27. PubMed ID: 24560789
[TBL] [Abstract][Full Text] [Related]
19. Structural Basis for Inhibition of Human Autotaxin by Four Potent Compounds with Distinct Modes of Binding.
Stein AJ; Bain G; Prodanovich P; Santini AM; Darlington J; Stelzer NM; Sidhu RS; Schaub J; Goulet L; Lonergan D; Calderon I; Evans JF; Hutchinson JH
Mol Pharmacol; 2015 Dec; 88(6):982-92. PubMed ID: 26371182
[TBL] [Abstract][Full Text] [Related]
20. Autotaxin and LPA receptor signaling in cancer.
Houben AJ; Moolenaar WH
Cancer Metastasis Rev; 2011 Dec; 30(3-4):557-65. PubMed ID: 22002750
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
