BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

135 related articles for article (PubMed ID: 27517472)

  • 41. Novel DNA topoisomerase IIα inhibitors from combined ligand- and structure-based virtual screening.
    Drwal MN; Marinello J; Manzo SG; Wakelin LP; Capranico G; Griffith R
    PLoS One; 2014; 9(12):e114904. PubMed ID: 25489853
    [TBL] [Abstract][Full Text] [Related]  

  • 42. N-acetyl-p-benzoquinone imine, the toxic metabolite of acetaminophen, is a topoisomerase II poison.
    Bender RP; Lindsey RH; Burden DA; Osheroff N
    Biochemistry; 2004 Mar; 43(12):3731-9. PubMed ID: 15035644
    [TBL] [Abstract][Full Text] [Related]  

  • 43. RAD54L2-mediated DNA damage avoidance pathway specifically preserves genome integrity in response to topoisomerase 2 poisons.
    Zhang H; Xiong Y; Sun Y; Park JM; Su D; Feng X; Keast S; Tang M; Huang M; Wang C; Srivastava M; Yang C; Zhu D; Chen Z; Li S; Yin L; Pommier Y; Chen J
    Sci Adv; 2023 Dec; 9(49):eadi6681. PubMed ID: 38055811
    [TBL] [Abstract][Full Text] [Related]  

  • 44. Genetic evidence for involvement of two distinct nonhomologous end-joining pathways in repair of topoisomerase II-mediated DNA damage.
    Adachi N; Iiizumi S; So S; Koyama H
    Biochem Biophys Res Commun; 2004 Jun; 318(4):856-61. PubMed ID: 15147950
    [TBL] [Abstract][Full Text] [Related]  

  • 45. A topoisomerase II poison screen of ethnomedicinal Thai plants using a yeast cell-based assay.
    Sangmalee S; Laorpaksa A; Sukrong S
    J Ethnopharmacol; 2012 Jul; 142(2):432-7. PubMed ID: 22735665
    [TBL] [Abstract][Full Text] [Related]  

  • 46. The retinoblastoma tumor suppressor protein is required for efficient processing and repair of trapped topoisomerase II-DNA-cleavable complexes.
    Xiao H; Goodrich DW
    Oncogene; 2005 Dec; 24(55):8105-13. PubMed ID: 16091739
    [TBL] [Abstract][Full Text] [Related]  

  • 47. Roles of DNA topoisomerase II isozymes in chemotherapy and secondary malignancies.
    Azarova AM; Lyu YL; Lin CP; Tsai YC; Lau JY; Wang JC; Liu LF
    Proc Natl Acad Sci U S A; 2007 Jun; 104(26):11014-9. PubMed ID: 17578914
    [TBL] [Abstract][Full Text] [Related]  

  • 48. Identification of a small-molecule inhibitor of DNA topoisomerase II by proteomic profiling.
    Kawatani M; Takayama H; Muroi M; Kimura S; Maekawa T; Osada H
    Chem Biol; 2011 Jun; 18(6):743-51. PubMed ID: 21700210
    [TBL] [Abstract][Full Text] [Related]  

  • 49. Proteasomal inhibition potentiates drugs targeting DNA topoisomerase II.
    Lee KC; Bramley RL; Cowell IG; Jackson GH; Austin CA
    Biochem Pharmacol; 2016 Mar; 103():29-39. PubMed ID: 26794000
    [TBL] [Abstract][Full Text] [Related]  

  • 50. The ATP-dependent chromatin remodelling enzyme Uls1 prevents Topoisomerase II poisoning.
    Swanston A; Zabrady K; Ferreira HC
    Nucleic Acids Res; 2019 Jul; 47(12):6172-6183. PubMed ID: 31106359
    [TBL] [Abstract][Full Text] [Related]  

  • 51. Evaluating the genotoxicity of topoisomerase-targeted antibiotics.
    Smart DJ; Lynch AM
    Mutagenesis; 2012 May; 27(3):359-65. PubMed ID: 22155972
    [TBL] [Abstract][Full Text] [Related]  

  • 52. Gossypol interferes with both type I and type II topoisomerase activities without generating strand breaks.
    Senarisoy M; Canturk P; Zencir S; Baran Y; Topcu Z
    Cell Biochem Biophys; 2013 May; 66(1):199-204. PubMed ID: 23161103
    [TBL] [Abstract][Full Text] [Related]  

  • 53. Oncofetal HMGA2 attenuates genotoxic damage induced by topoisomerase II target compounds through the regulation of local DNA topology.
    Ahmed SM; Dröge P
    Mol Oncol; 2019 Oct; 13(10):2062-2078. PubMed ID: 31271486
    [TBL] [Abstract][Full Text] [Related]  

  • 54. Targeting DNA topoisomerase II in cancer chemotherapy.
    Nitiss JL
    Nat Rev Cancer; 2009 May; 9(5):338-50. PubMed ID: 19377506
    [TBL] [Abstract][Full Text] [Related]  

  • 55. Broken by the Cut: A Journey into the Role of Topoisomerase II in DNA Fragility.
    Atkin ND; Raimer HM; Wang YH
    Genes (Basel); 2019 Oct; 10(10):. PubMed ID: 31614754
    [TBL] [Abstract][Full Text] [Related]  

  • 56. Effects of Olive Metabolites on DNA Cleavage Mediated by Human Type II Topoisomerases.
    Vann KR; Sedgeman CA; Gopas J; Golan-Goldhirsh A; Osheroff N
    Biochemistry; 2015 Jul; 54(29):4531-41. PubMed ID: 26132160
    [TBL] [Abstract][Full Text] [Related]  

  • 57. Bioassay-Guided Isolation of Two Flavonoids from Derris scandens with Topoisomerase II Poison Activity.
    Sangmalee S; Laorpaksa A; Sritularak B; Sukrong S
    Biol Pharm Bull; 2016; 39(4):631-5. PubMed ID: 26754253
    [TBL] [Abstract][Full Text] [Related]  

  • 58. Phenanthriplatin Acts As a Covalent Poison of Topoisomerase II Cleavage Complexes.
    Riddell IA; Agama K; Park GY; Pommier Y; Lippard SJ
    ACS Chem Biol; 2016 Nov; 11(11):2996-3001. PubMed ID: 27648475
    [TBL] [Abstract][Full Text] [Related]  

  • 59. Stimulation of topoisomerase II-mediated DNA damage via a mechanism involving protein thiolation.
    Wang H; Mao Y; Chen AY; Zhou N; LaVoie EJ; Liu LF
    Biochemistry; 2001 Mar; 40(11):3316-23. PubMed ID: 11258951
    [TBL] [Abstract][Full Text] [Related]  

  • 60. Effects of an unusual poison identify a lifespan role for Topoisomerase 2 in
    Tombline G; Millen JI; Polevoda B; Rapaport M; Baxter B; Van Meter M; Gilbertson M; Madrey J; Piazza GA; Rasmussen L; Wennerberg K; White EL; Nitiss JL; Goldfarb DS
    Aging (Albany NY); 2017 Jan; 9(1):68-97. PubMed ID: 28077781
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 7.