BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

161 related articles for article (PubMed ID: 27518808)

  • 1. IRE1α-XBP1 signaling pathway, a potential therapeutic target in multiple myeloma.
    Chen L; Li Q; She T; Li H; Yue Y; Gao S; Yan T; Liu S; Ma J; Wang Y
    Leuk Res; 2016 Oct; 49():7-12. PubMed ID: 27518808
    [TBL] [Abstract][Full Text] [Related]  

  • 2. IRE1α-XBP1 pathway promotes melanoma progression by regulating IL-6/STAT3 signaling.
    Chen C; Zhang X
    J Transl Med; 2017 Feb; 15(1):42. PubMed ID: 28222747
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Reduced response of IRE1α/Xbp-1 signaling pathway to bortezomib contributes to drug resistance in multiple myeloma cells.
    Xu X; Liu J; Huang B; Chen M; Yuan S; Li X; Li J
    Tumori; 2017 May; 103(3):261-267. PubMed ID: 27647225
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Disruption of IRE1α through its kinase domain attenuates multiple myeloma.
    Harnoss JM; Le Thomas A; Shemorry A; Marsters SA; Lawrence DA; Lu M; Chen YA; Qing J; Totpal K; Kan D; Segal E; Merchant M; Reichelt M; Ackerly Wallweber H; Wang W; Clark K; Kaufman S; Beresini MH; Laing ST; Sandoval W; Lorenzo M; Wu J; Ly J; De Bruyn T; Heidersbach A; Haley B; Gogineni A; Weimer RM; Lee D; Braun MG; Rudolph J; VanWyngarden MJ; Sherbenou DW; Gomez-Bougie P; Amiot M; Acosta-Alvear D; Walter P; Ashkenazi A
    Proc Natl Acad Sci U S A; 2019 Aug; 116(33):16420-16429. PubMed ID: 31371506
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Acridine Derivatives as Inhibitors of the IRE1α-XBP1 Pathway Are Cytotoxic to Human Multiple Myeloma.
    Jiang D; Tam AB; Alagappan M; Hay MP; Gupta A; Kozak MM; Solow-Cordero DE; Lum PY; Denko NC; Giaccia AJ; Le QT; Niwa M; Koong AC
    Mol Cancer Ther; 2016 Sep; 15(9):2055-65. PubMed ID: 27307600
    [TBL] [Abstract][Full Text] [Related]  

  • 6. KIRA8 attenuates non-alcoholic steatohepatitis through inhibition of the IRE1α/XBP1 signalling pathway.
    Zhao S; Liu X; Li L; Kong X; Sun W; Loomes K; Nie T; Hui X; Wu D
    Biochem Biophys Res Commun; 2022 Dec; 632():158-164. PubMed ID: 36209584
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Targeting signaling pathways in multiple myeloma: Pathogenesis and implication for treatments.
    Hu J; Hu WX
    Cancer Lett; 2018 Feb; 414():214-221. PubMed ID: 29174802
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Inhibition of IRE1α-driven pro-survival pathways is a promising therapeutic application in acute myeloid leukemia.
    Sun H; Lin DC; Guo X; Kharabi Masouleh B; Gery S; Cao Q; Alkan S; Ikezoe T; Akiba C; Paquette R; Chien W; Müller-Tidow C; Jing Y; Agelopoulos K; Müschen M; Koeffler HP
    Oncotarget; 2016 Apr; 7(14):18736-49. PubMed ID: 26934650
    [TBL] [Abstract][Full Text] [Related]  

  • 9. IRE1α-XBP1 is a novel branch in the transcriptional regulation of Ucp1 in brown adipocytes.
    Asada R; Kanemoto S; Matsuhisa K; Hino K; Cui M; Cui X; Kaneko M; Imaizumi K
    Sci Rep; 2015 Nov; 5():16580. PubMed ID: 26568450
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Identification of Doxorubicin as an Inhibitor of the IRE1α-XBP1 Axis of the Unfolded Protein Response.
    Jiang D; Lynch C; Medeiros BC; Liedtke M; Bam R; Tam AB; Yang Z; Alagappan M; Abidi P; Le QT; Giaccia AJ; Denko NC; Niwa M; Koong AC
    Sci Rep; 2016 Sep; 6():33353. PubMed ID: 27634301
    [TBL] [Abstract][Full Text] [Related]  

  • 11. IRE1-mediated unconventional mRNA splicing and S2P-mediated ATF6 cleavage merge to regulate XBP1 in signaling the unfolded protein response.
    Lee K; Tirasophon W; Shen X; Michalak M; Prywes R; Okada T; Yoshida H; Mori K; Kaufman RJ
    Genes Dev; 2002 Feb; 16(4):452-66. PubMed ID: 11850408
    [TBL] [Abstract][Full Text] [Related]  

  • 12. The molecular mechanisms of XBP-1 gene silencing on IRE1α-TRAF2-ASK1-JNK pathways in oral squamous cell carcinoma under endoplasmic reticulum stress.
    Chen H; Yang H; Pan L; Wang W; Liu X; Ren X; Liu Y; Liu W; Zhang Y; Jiang L; Li K; Zhang B; Wang LX
    Biomed Pharmacother; 2016 Feb; 77():108-13. PubMed ID: 26796273
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Targeting Adaptive IRE1α Signaling and PLK2 in Multiple Myeloma: Possible Anti-Tumor Mechanisms of KIRA8 and Nilotinib.
    Yamashita Y; Morita S; Hosoi H; Kobata H; Kishimoto S; Ishibashi T; Mishima H; Kinoshita A; Backes BJ; Yoshiura KI; Papa FR; Sonoki T; Tamura S
    Int J Mol Sci; 2020 Aug; 21(17):. PubMed ID: 32878237
    [TBL] [Abstract][Full Text] [Related]  

  • 14. IRE1α/XBP1-mediated branch of the unfolded protein response regulates osteoclastogenesis.
    Tohmonda T; Yoda M; Iwawaki T; Matsumoto M; Nakamura M; Mikoshiba K; Toyama Y; Horiuchi K
    J Clin Invest; 2015 Aug; 125(8):3269-79. PubMed ID: 26193638
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Positive contribution of the IRE1alpha-XBP1 pathway to placental expression of CEA family genes.
    Oikawa D; Akai R; Iwawaki T
    FEBS Lett; 2010 Mar; 584(5):1066-70. PubMed ID: 20146926
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Loss of p53 enhances the function of the endoplasmic reticulum through activation of the IRE1α/XBP1 pathway.
    Namba T; Chu K; Kodama R; Byun S; Yoon KW; Hiraki M; Mandinova A; Lee SW
    Oncotarget; 2015 Aug; 6(24):19990-20001. PubMed ID: 26254280
    [TBL] [Abstract][Full Text] [Related]  

  • 17. T-2 toxin inhibits the production of mucin via activating the IRE1/XBP1 pathway.
    Lin R; Sun Y; Ye W; Zheng T; Wen J; Deng Y
    Toxicology; 2019 Aug; 424():152230. PubMed ID: 31170431
    [TBL] [Abstract][Full Text] [Related]  

  • 18. A novel chemical, STF-083010, reverses tamoxifen-related drug resistance in breast cancer by inhibiting IRE1/XBP1.
    Ming J; Ruan S; Wang M; Ye D; Fan N; Meng Q; Tian B; Huang T
    Oncotarget; 2015 Dec; 6(38):40692-703. PubMed ID: 26517687
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Hepatic IRE1α regulates fasting-induced metabolic adaptive programs through the XBP1s-PPARα axis signalling.
    Shao M; Shan B; Liu Y; Deng Y; Yan C; Wu Y; Mao T; Qiu Y; Zhou Y; Jiang S; Jia W; Li J; Li J; Rui L; Yang L; Liu Y
    Nat Commun; 2014 Mar; 5():3528. PubMed ID: 24670948
    [TBL] [Abstract][Full Text] [Related]  

  • 20. IRE1α-XBP1 signaling pathway regulates IL-6 expression and promotes progression of hepatocellular carcinoma.
    Fang P; Xiang L; Huang S; Jin L; Zhou G; Zhuge L; Li J; Fan H; Zhou L; Pan C; Zheng Y
    Oncol Lett; 2018 Oct; 16(4):4729-4736. PubMed ID: 30214606
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.