BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

330 related articles for article (PubMed ID: 27519411)

  • 1. Architecture of the Human Mitochondrial Iron-Sulfur Cluster Assembly Machinery.
    Gakh O; Ranatunga W; Smith DY; Ahlgren EC; Al-Karadaghi S; Thompson JR; Isaya G
    J Biol Chem; 2016 Sep; 291(40):21296-21321. PubMed ID: 27519411
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Structure and functional dynamics of the mitochondrial Fe/S cluster synthesis complex.
    Boniecki MT; Freibert SA; Mühlenhoff U; Lill R; Cygler M
    Nat Commun; 2017 Nov; 8(1):1287. PubMed ID: 29097656
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Defining the Architecture of the Core Machinery for the Assembly of Fe-S Clusters in Human Mitochondria.
    Gakh O; Ranatunga W; Galeano BK; Smith DS; Thompson JR; Isaya G
    Methods Enzymol; 2017; 595():107-160. PubMed ID: 28882199
    [TBL] [Abstract][Full Text] [Related]  

  • 4. The N-Terminus of Iron-Sulfur Cluster Assembly Factor ISD11 Is Crucial for Subcellular Targeting and Interaction with l-Cysteine Desulfurase NFS1.
    Friemel M; Marelja Z; Li K; Leimkühler S
    Biochemistry; 2017 Mar; 56(12):1797-1808. PubMed ID: 28271877
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Normal and Friedreich ataxia cells express different isoforms of frataxin with complementary roles in iron-sulfur cluster assembly.
    Gakh O; Bedekovics T; Duncan SF; Smith DY; Berkholz DS; Isaya G
    J Biol Chem; 2010 Dec; 285(49):38486-501. PubMed ID: 20889968
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Architectural Features of Human Mitochondrial Cysteine Desulfurase Complexes from Crosslinking Mass Spectrometry and Small-Angle X-Ray Scattering.
    Cai K; Frederick RO; Dashti H; Markley JL
    Structure; 2018 Aug; 26(8):1127-1136.e4. PubMed ID: 29983374
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Architecture of the Yeast Mitochondrial Iron-Sulfur Cluster Assembly Machinery: THE SUB-COMPLEX FORMED BY THE IRON DONOR, Yfh1 PROTEIN, AND THE SCAFFOLD, Isu1 PROTEIN.
    Ranatunga W; Gakh O; Galeano BK; Smith DY; Söderberg CA; Al-Karadaghi S; Thompson JR; Isaya G
    J Biol Chem; 2016 May; 291(19):10378-98. PubMed ID: 26941001
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Zinc(II) binding on human wild-type ISCU and Met140 variants modulates NFS1 desulfurase activity.
    Fox NG; Martelli A; Nabhan JF; Janz J; Borkowska O; Bulawa C; Yue WW
    Biochimie; 2018 Sep; 152():211-218. PubMed ID: 30031876
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Structure of human Fe-S assembly subcomplex reveals unexpected cysteine desulfurase architecture and acyl-ACP-ISD11 interactions.
    Cory SA; Van Vranken JG; Brignole EJ; Patra S; Winge DR; Drennan CL; Rutter J; Barondeau DP
    Proc Natl Acad Sci U S A; 2017 Jul; 114(27):E5325-E5334. PubMed ID: 28634302
    [TBL] [Abstract][Full Text] [Related]  

  • 10. The Human Iron-Sulfur Assembly Complex Catalyzes the Synthesis of [2Fe-2S] Clusters on ISCU2 That Can Be Transferred to Acceptor Molecules.
    Fox NG; Chakrabarti M; McCormick SP; Lindahl PA; Barondeau DP
    Biochemistry; 2015 Jun; 54(25):3871-9. PubMed ID: 26016389
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Frataxin directly stimulates mitochondrial cysteine desulfurase by exposing substrate-binding sites, and a mutant Fe-S cluster scaffold protein with frataxin-bypassing ability acts similarly.
    Pandey A; Gordon DM; Pain J; Stemmler TL; Dancis A; Pain D
    J Biol Chem; 2013 Dec; 288(52):36773-86. PubMed ID: 24217246
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Mitochondrial frataxin interacts with ISD11 of the NFS1/ISCU complex and multiple mitochondrial chaperones.
    Shan Y; Napoli E; Cortopassi G
    Hum Mol Genet; 2007 Apr; 16(8):929-41. PubMed ID: 17331979
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Structure of the human frataxin-bound iron-sulfur cluster assembly complex provides insight into its activation mechanism.
    Fox NG; Yu X; Feng X; Bailey HJ; Martelli A; Nabhan JF; Strain-Damerell C; Bulawa C; Yue WW; Han S
    Nat Commun; 2019 May; 10(1):2210. PubMed ID: 31101807
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Mammalian frataxin: an essential function for cellular viability through an interaction with a preformed ISCU/NFS1/ISD11 iron-sulfur assembly complex.
    Schmucker S; Martelli A; Colin F; Page A; Wattenhofer-Donzé M; Reutenauer L; Puccio H
    PLoS One; 2011 Jan; 6(1):e16199. PubMed ID: 21298097
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Human Mitochondrial Ferredoxin 1 (FDX1) and Ferredoxin 2 (FDX2) Both Bind Cysteine Desulfurase and Donate Electrons for Iron-Sulfur Cluster Biosynthesis.
    Cai K; Tonelli M; Frederick RO; Markley JL
    Biochemistry; 2017 Jan; 56(3):487-499. PubMed ID: 28001042
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Mapping Key Residues of ISD11 Critical for NFS1-ISD11 Subcomplex Stability: IMPLICATIONS IN THE DEVELOPMENT OF MITOCHONDRIAL DISORDER, COXPD19.
    Saha PP; Srivastava S; Kumar S K P; Sinha D; D'Silva P
    J Biol Chem; 2015 Oct; 290(43):25876-90. PubMed ID: 26342079
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Interactions of iron-bound frataxin with ISCU and ferredoxin on the cysteine desulfurase complex leading to Fe-S cluster assembly.
    Cai K; Frederick RO; Tonelli M; Markley JL
    J Inorg Biochem; 2018 Jun; 183():107-116. PubMed ID: 29576242
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Human mitochondrial chaperone (mtHSP70) and cysteine desulfurase (NFS1) bind preferentially to the disordered conformation, whereas co-chaperone (HSC20) binds to the structured conformation of the iron-sulfur cluster scaffold protein (ISCU).
    Cai K; Frederick RO; Kim JH; Reinen NM; Tonelli M; Markley JL
    J Biol Chem; 2013 Oct; 288(40):28755-70. PubMed ID: 23940031
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Molecular Details of the Frataxin-Scaffold Interaction during Mitochondrial Fe-S Cluster Assembly.
    Campbell CJ; Pall AE; Naik AR; Thompson LN; Stemmler TL
    Int J Mol Sci; 2021 Jun; 22(11):. PubMed ID: 34199378
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Mechanisms of Mitochondrial Iron-Sulfur Protein Biogenesis.
    Lill R; Freibert SA
    Annu Rev Biochem; 2020 Jun; 89():471-499. PubMed ID: 31935115
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 17.