131 related articles for article (PubMed ID: 27519818)
1. Sphingosine-1-Phosphate (S1P) Lyase Inhibition Causes Increased Cardiac S1P Levels and Bradycardia in Rats.
Harris CM; Mittelstadt S; Banfor P; Bousquet P; Duignan DB; Gintant G; Hart M; Kim Y; Segreti J
J Pharmacol Exp Ther; 2016 Oct; 359(1):151-8. PubMed ID: 27519818
[TBL] [Abstract][Full Text] [Related]
2. Incomplete inhibition of sphingosine 1-phosphate lyase modulates immune system function yet prevents early lethality and non-lymphoid lesions.
Vogel P; Donoviel MS; Read R; Hansen GM; Hazlewood J; Anderson SJ; Sun W; Swaffield J; Oravecz T
PLoS One; 2009; 4(1):e4112. PubMed ID: 19119317
[TBL] [Abstract][Full Text] [Related]
3. Protection of LPS-induced murine acute lung injury by sphingosine-1-phosphate lyase suppression.
Zhao Y; Gorshkova IA; Berdyshev E; He D; Fu P; Ma W; Su Y; Usatyuk PV; Pendyala S; Oskouian B; Saba JD; Garcia JG; Natarajan V
Am J Respir Cell Mol Biol; 2011 Aug; 45(2):426-35. PubMed ID: 21148740
[TBL] [Abstract][Full Text] [Related]
4. Sphingosine-1-Phosphate Lyase Inhibition Alters the S1P Gradient and Ameliorates Crohn's-Like Ileitis by Suppressing Thymocyte Maturation.
Karuppuchamy T; Tyler CJ; Lundborg LR; Pérez-Jeldres T; Kimball AK; Clambey ET; Jedlicka P; Rivera-Nieves J
Inflamm Bowel Dis; 2020 Jan; 26(2):216-228. PubMed ID: 31807751
[TBL] [Abstract][Full Text] [Related]
5. A systematic methodology for large scale compound screening: A case study on the discovery of novel S1PL inhibitors.
Deniz U; Ozkirimli E; Ulgen KO
J Mol Graph Model; 2016 Jan; 63():110-24. PubMed ID: 26724452
[TBL] [Abstract][Full Text] [Related]
6. Lymphocyte sequestration through S1P lyase inhibition and disruption of S1P gradients.
Schwab SR; Pereira JP; Matloubian M; Xu Y; Huang Y; Cyster JG
Science; 2005 Sep; 309(5741):1735-9. PubMed ID: 16151014
[TBL] [Abstract][Full Text] [Related]
7. Aryl hydrocarbon receptor signaling promotes ORMDL3-dependent generation of sphingosine-1-phosphate by inhibiting sphingosine-1-phosphate lyase.
Wang HC; Wong TH; Wang LT; Su HH; Yu HY; Wu AH; Lin YC; Chen HL; Suen JL; Hsu SH; Chen LC; Zhou Y; Huang SK
Cell Mol Immunol; 2019 Oct; 16(10):783-790. PubMed ID: 29572542
[TBL] [Abstract][Full Text] [Related]
8. Immune cell regulation and cardiovascular effects of sphingosine 1-phosphate receptor agonists in rodents are mediated via distinct receptor subtypes.
Forrest M; Sun SY; Hajdu R; Bergstrom J; Card D; Doherty G; Hale J; Keohane C; Meyers C; Milligan J; Mills S; Nomura N; Rosen H; Rosenbach M; Shei GJ; Singer II; Tian M; West S; White V; Xie J; Proia RL; Mandala S
J Pharmacol Exp Ther; 2004 May; 309(2):758-68. PubMed ID: 14747617
[TBL] [Abstract][Full Text] [Related]
9. Inhibition of sphingosine-1-phosphate lyase rescues sphingosine kinase-1-knockout phenotype following murine cardiac arrest.
Gorshkova IA; Wang H; Orbelyan GA; Goya J; Natarajan V; Beiser DG; Vanden Hoek TL; Berdyshev EV
Life Sci; 2013 Sep; 93(9-11):359-66. PubMed ID: 23892195
[TBL] [Abstract][Full Text] [Related]
10. Characterization of secreted sphingosine-1-phosphate lyases required for virulence and intracellular survival of Burkholderia pseudomallei.
Custódio R; McLean CJ; Scott AE; Lowther J; Kennedy A; Clarke DJ; Campopiano DJ; Sarkar-Tyson M; Brown AR
Mol Microbiol; 2016 Dec; 102(6):1004-1019. PubMed ID: 27632710
[TBL] [Abstract][Full Text] [Related]
11. Characterization of sphingosine-1-phosphate lyase activity by electrospray ionization-liquid chromatography/tandem mass spectrometry quantitation of (2E)-hexadecenal.
Berdyshev EV; Goya J; Gorshkova I; Prestwich GD; Byun HS; Bittman R; Natarajan V
Anal Biochem; 2011 Jan; 408(1):12-8. PubMed ID: 20804717
[TBL] [Abstract][Full Text] [Related]
12. Intracellular S1P generation is essential for S1P-induced motility of human lung endothelial cells: role of sphingosine kinase 1 and S1P lyase.
Berdyshev EV; Gorshkova I; Usatyuk P; Kalari S; Zhao Y; Pyne NJ; Pyne S; Sabbadini RA; Garcia JG; Natarajan V
PLoS One; 2011 Jan; 6(1):e16571. PubMed ID: 21304987
[TBL] [Abstract][Full Text] [Related]
13. Inhibition of sphingosine-1-phosphate lyase for the treatment of autoimmune disorders.
Bagdanoff JT; Donoviel MS; Nouraldeen A; Tarver J; Fu Q; Carlsen M; Jessop TC; Zhang H; Hazelwood J; Nguyen H; Baugh SD; Gardyan M; Terranova KM; Barbosa J; Yan J; Bednarz M; Layek S; Courtney LF; Taylor J; Digeorge-Foushee AM; Gopinathan S; Bruce D; Smith T; Moran L; O'Neill E; Kramer J; Lai Z; Kimball SD; Liu Q; Sun W; Yu S; Swaffield J; Wilson A; Main A; Carson KG; Oravecz T; Augeri DJ
J Med Chem; 2009 Jul; 52(13):3941-53. PubMed ID: 19489538
[TBL] [Abstract][Full Text] [Related]
14. Sphingosine-1-phosphate: boon and bane for the brain.
van Echten-Deckert G; Hagen-Euteneuer N; Karaca I; Walter J
Cell Physiol Biochem; 2014; 34(1):148-57. PubMed ID: 24977488
[TBL] [Abstract][Full Text] [Related]
15. The clinically-tested S1P receptor agonists, FTY720 and BAF312, demonstrate subtype-specific bradycardia (S1P₁) and hypertension (S1P₃) in rat.
Fryer RM; Muthukumarana A; Harrison PC; Nodop Mazurek S; Chen RR; Harrington KE; Dinallo RM; Horan JC; Patnaude L; Modis LK; Reinhart GA
PLoS One; 2012; 7(12):e52985. PubMed ID: 23285242
[TBL] [Abstract][Full Text] [Related]
16. Inhibition of sphingosine 1-phosphate lyase activates human keratinocyte differentiation and attenuates psoriasis in mice.
Jeon S; Song J; Lee D; Kim GT; Park SH; Shin DY; Shin KO; Park K; Shim SM; Park TS
J Lipid Res; 2020 Jan; 61(1):20-32. PubMed ID: 31690639
[TBL] [Abstract][Full Text] [Related]
17. Assay to measure the secretion of sphingosine-1-phosphate from cells induced by S1P lyase inhibitors.
Loetscher E; Schneider K; Beerli C; Billich A
Biochem Biophys Res Commun; 2013 Apr; 433(3):345-8. PubMed ID: 23499842
[TBL] [Abstract][Full Text] [Related]
18. The lysophospholipids sphingosine-1-phosphate and lysophosphatidic acid enhance survival during hypoxia in neonatal rat cardiac myocytes.
Karliner JS; Honbo N; Summers K; Gray MO; Goetzl EJ
J Mol Cell Cardiol; 2001 Sep; 33(9):1713-7. PubMed ID: 11549349
[TBL] [Abstract][Full Text] [Related]
19. Scintillation Proximity Assay to Detect the Changes in Cellular Dihydrosphingosine 1-Phosphate Levels.
Ohtoyo M; Tamura M; Machinaga N; Muro F; Hashimoto R
Lipids; 2016 Oct; 51(10):1207-1216. PubMed ID: 27585475
[TBL] [Abstract][Full Text] [Related]
20. Component of Caramel Food Coloring, THI, Causes Lymphopenia Indirectly via a Key Metabolic Intermediate.
Ohtoyo M; Machinaga N; Inoue R; Hagihara K; Yuita H; Tamura M; Hashimoto R; Chiba J; Muro F; Watanabe J; Kobayashi Y; Abe K; Kita Y; Nagasaki M; Shimozato T
Cell Chem Biol; 2016 May; 23(5):555-560. PubMed ID: 27185637
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
