BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

316 related articles for article (PubMed ID: 27522463)

  • 1. Cryo-EM of Mitotic Checkpoint Complex-Bound APC/C Reveals Reciprocal and Conformational Regulation of Ubiquitin Ligation.
    Yamaguchi M; VanderLinden R; Weissmann F; Qiao R; Dube P; Brown NG; Haselbach D; Zhang W; Sidhu SS; Peters JM; Stark H; Schulman BA
    Mol Cell; 2016 Aug; 63(4):593-607. PubMed ID: 27522463
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Molecular basis of APC/C regulation by the spindle assembly checkpoint.
    Alfieri C; Chang L; Zhang Z; Yang J; Maslen S; Skehel M; Barford D
    Nature; 2016 Aug; 536(7617):431-436. PubMed ID: 27509861
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Fission Yeast Apc15 Stabilizes MCC-Cdc20-APC/C Complexes, Ensuring Efficient Cdc20 Ubiquitination and Checkpoint Arrest.
    May KM; Paldi F; Hardwick KG
    Curr Biol; 2017 Apr; 27(8):1221-1228. PubMed ID: 28366744
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Structure of the anaphase-promoting complex/cyclosome interacting with a mitotic checkpoint complex.
    Herzog F; Primorac I; Dube P; Lenart P; Sander B; Mechtler K; Stark H; Peters JM
    Science; 2009 Mar; 323(5920):1477-81. PubMed ID: 19286556
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Role of ubiquitylation of components of mitotic checkpoint complex in their dissociation from anaphase-promoting complex/cyclosome.
    Sitry-Shevah D; Kaisari S; Teichner A; Miniowitz-Shemtov S; Hershko A
    Proc Natl Acad Sci U S A; 2018 Feb; 115(8):1777-1782. PubMed ID: 29432156
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Atomic structure of the APC/C and its mechanism of protein ubiquitination.
    Chang L; Zhang Z; Yang J; McLaughlin SH; Barford D
    Nature; 2015 Jun; 522(7557):450-454. PubMed ID: 26083744
    [TBL] [Abstract][Full Text] [Related]  

  • 7. The mitotic checkpoint complex binds a second CDC20 to inhibit active APC/C.
    Izawa D; Pines J
    Nature; 2015 Jan; 517(7536):631-4. PubMed ID: 25383541
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Dual RING E3 Architectures Regulate Multiubiquitination and Ubiquitin Chain Elongation by APC/C.
    Brown NG; VanderLinden R; Watson ER; Weissmann F; Ordureau A; Wu KP; Zhang W; Yu S; Mercredi PY; Harrison JS; Davidson IF; Qiao R; Lu Y; Dube P; Brunner MR; Grace CRR; Miller DJ; Haselbach D; Jarvis MA; Yamaguchi M; Yanishevski D; Petzold G; Sidhu SS; Kuhlman B; Kirschner MW; Harper JW; Peters JM; Stark H; Schulman BA
    Cell; 2016 Jun; 165(6):1440-1453. PubMed ID: 27259151
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Stable MCC binding to the APC/C is required for a functional spindle assembly checkpoint.
    Hein JB; Nilsson J
    EMBO Rep; 2014 Mar; 15(3):264-72. PubMed ID: 24464857
    [TBL] [Abstract][Full Text] [Related]  

  • 10. APC15 mediates CDC20 autoubiquitylation by APC/C(MCC) and disassembly of the mitotic checkpoint complex.
    Uzunova K; Dye BT; Schutz H; Ladurner R; Petzold G; Toyoda Y; Jarvis MA; Brown NG; Poser I; Novatchkova M; Mechtler K; Hyman AA; Stark H; Schulman BA; Peters JM
    Nat Struct Mol Biol; 2012 Nov; 19(11):1116-23. PubMed ID: 23007861
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Molecular mechanism of APC/C activation by mitotic phosphorylation.
    Zhang S; Chang L; Alfieri C; Zhang Z; Yang J; Maslen S; Skehel M; Barford D
    Nature; 2016 May; 533(7602):260-264. PubMed ID: 27120157
    [TBL] [Abstract][Full Text] [Related]  

  • 12. An E2 enzyme Ubc11 is required for ubiquitination of Slp1/Cdc20 and spindle checkpoint silencing in fission yeast.
    Horikoshi Y; Habu T; Matsumoto T
    Cell Cycle; 2013 Mar; 12(6):961-71. PubMed ID: 23442800
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Mitotic phosphatase activity is required for MCC maintenance during the spindle checkpoint.
    Foss KM; Robeson AC; Kornbluth S; Zhang L
    Cell Cycle; 2016; 15(2):225-33. PubMed ID: 26652909
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Ubiquitination by the anaphase-promoting complex drives spindle checkpoint inactivation.
    Reddy SK; Rape M; Margansky WA; Kirschner MW
    Nature; 2007 Apr; 446(7138):921-5. PubMed ID: 17443186
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Structure of the mitotic checkpoint complex.
    Chao WC; Kulkarni K; Zhang Z; Kong EH; Barford D
    Nature; 2012 Mar; 484(7393):208-13. PubMed ID: 22437499
    [TBL] [Abstract][Full Text] [Related]  

  • 16. The APC/C subunit Mnd2/Apc15 promotes Cdc20 autoubiquitination and spindle assembly checkpoint inactivation.
    Foster SA; Morgan DO
    Mol Cell; 2012 Sep; 47(6):921-32. PubMed ID: 22940250
    [TBL] [Abstract][Full Text] [Related]  

  • 17. APC15 drives the turnover of MCC-CDC20 to make the spindle assembly checkpoint responsive to kinetochore attachment.
    Mansfeld J; Collin P; Collins MO; Choudhary JS; Pines J
    Nat Cell Biol; 2011 Sep; 13(10):1234-43. PubMed ID: 21926987
    [TBL] [Abstract][Full Text] [Related]  

  • 18. The Bub1-Plk1 kinase complex promotes spindle checkpoint signalling through Cdc20 phosphorylation.
    Jia L; Li B; Yu H
    Nat Commun; 2016 Feb; 7():10818. PubMed ID: 26912231
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Intermediates in the assembly of mitotic checkpoint complexes and their role in the regulation of the anaphase-promoting complex.
    Kaisari S; Sitry-Shevah D; Miniowitz-Shemtov S; Hershko A
    Proc Natl Acad Sci U S A; 2016 Jan; 113(4):966-71. PubMed ID: 26755599
    [TBL] [Abstract][Full Text] [Related]  

  • 20. BubR1 blocks substrate recruitment to the APC/C in a KEN-box-dependent manner.
    Lara-Gonzalez P; Scott MI; Diez M; Sen O; Taylor SS
    J Cell Sci; 2011 Dec; 124(Pt 24):4332-45. PubMed ID: 22193957
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 16.