These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

272 related articles for article (PubMed ID: 27527871)

  • 1. Prolyl hydroxylase 2 (PHD2) inhibition protects human renal epithelial cells and mice kidney from hypoxia injury.
    Fang Y; Zhang H; Zhong Y; Ding X
    Oncotarget; 2016 Aug; 7(34):54317-54328. PubMed ID: 27527871
    [TBL] [Abstract][Full Text] [Related]  

  • 2. miR-21 contributes to renal protection by targeting prolyl hydroxylase domain protein 2 in delayed ischaemic preconditioning.
    Jiao X; Xu X; Fang Y; Zhang H; Liang M; Teng J; Ding X
    Nephrology (Carlton); 2017 May; 22(5):366-373. PubMed ID: 27030384
    [TBL] [Abstract][Full Text] [Related]  

  • 3. HIF-prolyl hydroxylase 2 inhibition enhances the efficiency of mesenchymal stem cell-based therapies for the treatment of critical limb ischemia.
    HoWangYin KY; Loinard C; Bakker W; Guérin CL; Vilar J; d'Audigier C; Mauge L; Bruneval P; Emmerich J; Lévy BI; Pouysségur J; Smadja DM; Silvestre JS
    Stem Cells; 2014 Jan; 32(1):231-43. PubMed ID: 24105925
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Tetramethylpyrazine protects CoCl2-induced apoptosis in human umbilical vein endothelial cells by regulating the PHD2/HIF/1α-VEGF pathway.
    Yang C; Xu Y; Zhou H; Yang L; Yu S; Gao Y; Huang Y; Lu L; Liang X
    Mol Med Rep; 2016 Feb; 13(2):1287-96. PubMed ID: 26676934
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Inhibition of Endothelial PHD2 Suppresses Post-Ischemic Kidney Inflammation through Hypoxia-Inducible Factor-1.
    Rajendran G; Schonfeld MP; Tiwari R; Huang S; Torosyan R; Fields T; Park J; Susztak K; Kapitsinou PP
    J Am Soc Nephrol; 2020 Mar; 31(3):501-516. PubMed ID: 31996410
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Hypoxia inducible factor-1 activation by prolyl 4-hydroxylase-2 gene silencing attenuates myocardial ischemia reperfusion injury.
    Natarajan R; Salloum FN; Fisher BJ; Kukreja RC; Fowler AA
    Circ Res; 2006 Jan; 98(1):133-40. PubMed ID: 16306444
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Complement C1q is hydroxylated by collagen prolyl 4 hydroxylase and is sensitive to off-target inhibition by prolyl hydroxylase domain inhibitors that stabilize hypoxia-inducible factor.
    Kiriakidis S; Hoer SS; Burrows N; Biddlecome G; Khan MN; Thinnes CC; Schofield CJ; Rogers N; Botto M; Paleolog E; Maxwell PH
    Kidney Int; 2017 Oct; 92(4):900-908. PubMed ID: 28506759
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Prolyl hydroxylase domain 2 deficiency promotes skeletal muscle fiber-type transition via a calcineurin/NFATc1-dependent pathway.
    Shin J; Nunomiya A; Kitajima Y; Dan T; Miyata T; Nagatomi R
    Skelet Muscle; 2016; 6():5. PubMed ID: 26949511
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Hypoxia-inducible factor-1 (HIF-1) promotes its degradation by induction of HIF-alpha-prolyl-4-hydroxylases.
    Marxsen JH; Stengel P; Doege K; Heikkinen P; Jokilehto T; Wagner T; Jelkmann W; Jaakkola P; Metzen E
    Biochem J; 2004 Aug; 381(Pt 3):761-7. PubMed ID: 15104534
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Endothelial prolyl hydroxylase 2 is necessary for angiotensin II-mediated renal fibrosis and injury.
    Zhao Y; Zeng H; Liu B; He X; Chen JX
    Am J Physiol Renal Physiol; 2020 Aug; 319(2):F345-F357. PubMed ID: 32715763
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Expression and actions of HIF prolyl-4-hydroxylase in the rat kidneys.
    Li N; Yi F; Sundy CM; Chen L; Hilliker ML; Donley DK; Muldoon DB; Li PL
    Am J Physiol Renal Physiol; 2007 Jan; 292(1):F207-16. PubMed ID: 16885149
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Endothelin-converting enzyme is a plausible target gene for hypoxia-inducible factor.
    Khamaisi M; Toukan H; Axelrod JH; Rosenberger C; Skarzinski G; Shina A; Meidan R; Koesters R; Rosen S; Walkinshaw G; Mimura I; Nangaku M; Heyman SN
    Kidney Int; 2015 Apr; 87(4):761-70. PubMed ID: 25469848
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Direct Peritoneal Resuscitation with Pyruvate Protects the Spinal Cord and Induces Autophagy via Regulating PHD2 in a Rat Model of Spinal Cord Ischemia-Reperfusion Injury.
    Xiong Y; Xia Y; Deng J; Yan X; Ke J; Zhan J; Zhang Z; Wang Y
    Oxid Med Cell Longev; 2020; 2020():4909103. PubMed ID: 31998438
    [TBL] [Abstract][Full Text] [Related]  

  • 14. The NADPH oxidase inhibitor DPI can abolish hypoxia-induced apoptosis of human kidney proximal tubular epithelial cells through Bcl2 up-regulation via ERK activation without ROS reduction.
    Song H; Han IY; Kim Y; Kim YH; Choi IW; Seo SK; Jung SY; Park S; Kang MS
    Life Sci; 2015 Apr; 126():69-75. PubMed ID: 25744050
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Inhibition of prolyl hydroxylase domain-containing protein on hypertension/renal injury induced by high salt diet and nitric oxide withdrawal.
    Dallatu MK; Choi M; Oyekan AO
    J Hypertens; 2013 Oct; 31(10):2043-9. PubMed ID: 23811999
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Neuron-specific prolyl-4-hydroxylase domain 2 knockout reduces brain injury after transient cerebral ischemia.
    Kunze R; Zhou W; Veltkamp R; Wielockx B; Breier G; Marti HH
    Stroke; 2012 Oct; 43(10):2748-56. PubMed ID: 22933585
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Kidney-Targeted Delivery of Prolyl Hydroxylase Domain Protein 2 Small Interfering RNA with Nanoparticles Alleviated Renal Ischemia/Reperfusion Injury.
    Xie D; Wang J; Hu G; Chen C; Yang H; Ritter JK; Qu Y; Li N
    J Pharmacol Exp Ther; 2021 Sep; 378(3):235-243. PubMed ID: 34103333
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Application of in-vitro screening methods on hypoxia inducible factor prolyl hydroxylase inhibitors.
    Wu Y; Jiang Z; You Q; Zhang X
    Bioorg Med Chem; 2017 Aug; 25(15):3891-3899. PubMed ID: 28625716
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Inhibition of oxygen-sensing prolyl hydroxylases increases lipid accumulation in human primary tubular epithelial cells without inducing ER stress.
    Schley G; Grampp S; Goppelt-Struebe M
    Cell Tissue Res; 2020 Jul; 381(1):125-140. PubMed ID: 32189058
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Lipopolysaccharide-induced cross-tolerance against renal ischemia-reperfusion injury is mediated by hypoxia-inducible factor-2α-regulated nitric oxide production.
    He K; Chen X; Han C; Xu L; Zhang J; Zhang M; Xia Q
    Kidney Int; 2014 Feb; 85(2):276-88. PubMed ID: 24025643
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 14.