BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

264 related articles for article (PubMed ID: 27537525)

  • 1. Bcl-xL is an oncogenic driver in colorectal cancer.
    Scherr AL; Gdynia G; Salou M; Radhakrishnan P; Duglova K; Heller A; Keim S; Kautz N; Jassowicz A; Elssner C; He YW; Jaeger D; Heikenwalder M; Schneider M; Weber A; Roth W; Schulze-Bergkamen H; Koehler BC
    Cell Death Dis; 2016 Aug; 7(8):e2342. PubMed ID: 27537525
    [TBL] [Abstract][Full Text] [Related]  

  • 2. The Bcl-xL inhibitor, ABT-737, efficiently induces apoptosis and suppresses growth of hepatoma cells in combination with sorafenib.
    Hikita H; Takehara T; Shimizu S; Kodama T; Shigekawa M; Iwase K; Hosui A; Miyagi T; Tatsumi T; Ishida H; Li W; Kanto T; Hiramatsu N; Hayashi N
    Hepatology; 2010 Oct; 52(4):1310-21. PubMed ID: 20799354
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Bcl-xL inhibition by molecular-targeting drugs sensitizes human pancreatic cancer cells to TRAIL.
    Hari Y; Harashima N; Tajima Y; Harada M
    Oncotarget; 2015 Dec; 6(39):41902-15. PubMed ID: 26506422
    [TBL] [Abstract][Full Text] [Related]  

  • 4. NF1 deficiency causes Bcl-xL upregulation in Schwann cells derived from neurofibromatosis type 1-associated malignant peripheral nerve sheath tumors.
    Park HJ; Lee SJ; Sohn YB; Jin HS; Han JH; Kim YB; Yim H; Jeong SY
    Int J Oncol; 2013 Feb; 42(2):657-66. PubMed ID: 23292448
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Inhibition of Bcl-xL by ABT-737 enhances chemotherapy sensitivity in neurofibromatosis type 1-associated malignant peripheral nerve sheath tumor cells.
    Lee SJ; Park HJ; Kim YH; Kim BY; Jin HS; Kim HJ; Han JH; Yim H; Jeong SY
    Int J Mol Med; 2012 Aug; 30(2):443-50. PubMed ID: 22664653
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Hypertonicity-imposed BCL-XL addiction primes colorectal cancer cells for death.
    Heimer S; Knoll G; Steixner C; Calance DN; Trinh DT; Ehrenschwender M
    Cancer Lett; 2018 Oct; 435():23-31. PubMed ID: 30075205
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Directed elimination of senescent cells by inhibition of BCL-W and BCL-XL.
    Yosef R; Pilpel N; Tokarsky-Amiel R; Biran A; Ovadya Y; Cohen S; Vadai E; Dassa L; Shahar E; Condiotti R; Ben-Porath I; Krizhanovsky V
    Nat Commun; 2016 Apr; 7():11190. PubMed ID: 27048913
    [TBL] [Abstract][Full Text] [Related]  

  • 8. ABT-737 Synergizes with Cisplatin Bypassing Aberration of Apoptotic Pathway in Non-small Cell Lung Cancer.
    Kim EY; Jung JY; Kim A; Chang YS; Kim SK
    Neoplasia; 2017 Apr; 19(4):354-363. PubMed ID: 28319809
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Pan-Bcl-2 inhibitor Obatoclax is a potent late stage autophagy inhibitor in colorectal cancer cells independent of canonical autophagy signaling.
    Koehler BC; Jassowicz A; Scherr AL; Lorenz S; Radhakrishnan P; Kautz N; Elssner C; Weiss J; Jaeger D; Schneider M; Schulze-Bergkamen H
    BMC Cancer; 2015 Nov; 15():919. PubMed ID: 26585594
    [TBL] [Abstract][Full Text] [Related]  

  • 10. The apoptosis inhibitor Bcl-xL controls breast cancer cell migration through mitochondria-dependent reactive oxygen species production.
    Bessou M; Lopez J; Gadet R; Deygas M; Popgeorgiev N; Poncet D; Nougarède A; Billard P; Mikaelian I; Gonzalo P; Rimokh R; Gillet G
    Oncogene; 2020 Apr; 39(15):3056-3074. PubMed ID: 32066881
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Inhibition of Bcl-2 and Bcl-X enhances chemotherapy sensitivity in hepatoblastoma cells.
    Lieber J; Kirchner B; Eicher C; Warmann SW; Seitz G; Fuchs J; Armeanu-Ebinger S
    Pediatr Blood Cancer; 2010 Dec; 55(6):1089-95. PubMed ID: 20680965
    [TBL] [Abstract][Full Text] [Related]  

  • 12. The Bcl-2/Bcl-XL inhibitor ABT-737 promotes death of retinoblastoma cancer cells.
    Allaman-Pillet N; Oberson A; Munier F; Schorderet DF
    Ophthalmic Genet; 2013; 34(1-2):1-13. PubMed ID: 21955141
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Mcl-1 down-regulation potentiates ABT-737 lethality by cooperatively inducing Bak activation and Bax translocation.
    Chen S; Dai Y; Harada H; Dent P; Grant S
    Cancer Res; 2007 Jan; 67(2):782-91. PubMed ID: 17234790
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Elimination of quiescent/slow-proliferating cancer stem cells by Bcl-XL inhibition in non-small cell lung cancer.
    Zeuner A; Francescangeli F; Contavalli P; Zapparelli G; Apuzzo T; Eramo A; Baiocchi M; De Angelis ML; Biffoni M; Sette G; Todaro M; Stassi G; De Maria R
    Cell Death Differ; 2014 Dec; 21(12):1877-88. PubMed ID: 25034785
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Inhibition of Bcl-xL prevents pro-death actions of ΔN-Bcl-xL at the mitochondrial inner membrane during glutamate excitotoxicity.
    Park HA; Licznerski P; Mnatsakanyan N; Niu Y; Sacchetti S; Wu J; Polster BM; Alavian KN; Jonas EA
    Cell Death Differ; 2017 Nov; 24(11):1963-1974. PubMed ID: 28777375
    [TBL] [Abstract][Full Text] [Related]  

  • 16. The Bcl-2/Bcl-XL family inhibitor ABT-737 sensitizes ovarian cancer cells to carboplatin.
    Witham J; Valenti MR; De-Haven-Brandon AK; Vidot S; Eccles SA; Kaye SB; Richardson A
    Clin Cancer Res; 2007 Dec; 13(23):7191-8. PubMed ID: 18056200
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Targeting ERK1/2-bim signaling cascades by BH3-mimetic ABT-737 as an alternative therapeutic strategy for oral cancer.
    Shin JA; Kim LH; Lee SJ; Jeong JH; Jung JY; Lee HN; Hong IS; Cho SD
    Oncotarget; 2015 Nov; 6(34):35667-83. PubMed ID: 26447615
    [TBL] [Abstract][Full Text] [Related]  

  • 18. A brewing understanding of the regulation of Bax function by Bcl-xL and Bcl-2.
    Renault TT; Dejean LM; Manon S
    Mech Ageing Dev; 2017 Jan; 161(Pt B):201-210. PubMed ID: 27112371
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Bcl-xL controls a switch between cell death modes during mitotic arrest.
    Bah N; Maillet L; Ryan J; Dubreil S; Gautier F; Letai A; Juin P; Barillé-Nion S
    Cell Death Dis; 2014 Jun; 5(6):e1291. PubMed ID: 24922075
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Bcl-xL stimulates Bax relocation to mitochondria and primes cells to ABT-737.
    Renault TT; Teijido O; Missire F; Ganesan YT; Velours G; Arokium H; Beaumatin F; Llanos R; Athané A; Camougrand N; Priault M; Antonsson B; Dejean LM; Manon S
    Int J Biochem Cell Biol; 2015 Jul; 64():136-46. PubMed ID: 25862283
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 14.