216 related articles for article (PubMed ID: 27538695)
1. Markov models of the apo-MDM2 lid region reveal diffuse yet two-state binding dynamics and receptor poses for computational docking.
Mukherjee S; Pantelopulos GA; Voelz VA
Sci Rep; 2016 Aug; 6():31631. PubMed ID: 27538695
[TBL] [Abstract][Full Text] [Related]
2. Quantitative lid dynamics of MDM2 reveals differential ligand binding modes of the p53-binding cleft.
Showalter SA; Bruschweiler-Li L; Johnson E; Zhang F; Brüschweiler R
J Am Chem Soc; 2008 May; 130(20):6472-8. PubMed ID: 18435534
[TBL] [Abstract][Full Text] [Related]
3. Microsecond simulations of mdm2 and its complex with p53 yield insight into force field accuracy and conformational dynamics.
Pantelopulos GA; Mukherjee S; Voelz VA
Proteins; 2015 Sep; 83(9):1665-76. PubMed ID: 26138282
[TBL] [Abstract][Full Text] [Related]
4. Simulating molecular mechanisms of the MDM2-mediated regulatory interactions: a conformational selection model of the MDM2 lid dynamics.
Verkhivker GM
PLoS One; 2012; 7(7):e40897. PubMed ID: 22815859
[TBL] [Abstract][Full Text] [Related]
5. Binding induced folding in p53-MDM2 complex.
Chen HF; Luo R
J Am Chem Soc; 2007 Mar; 129(10):2930-7. PubMed ID: 17302414
[TBL] [Abstract][Full Text] [Related]
6. Elucidation of Ligand-Dependent Modulation of Disorder-Order Transitions in the Oncoprotein MDM2.
Bueren-Calabuig JA; Michel J
PLoS Comput Biol; 2015 Jun; 11(6):e1004282. PubMed ID: 26046940
[TBL] [Abstract][Full Text] [Related]
7. Protein-peptide molecular docking with large-scale conformational changes: the p53-MDM2 interaction.
Ciemny MP; Debinski A; Paczkowska M; Kolinski A; Kurcinski M; Kmiecik S
Sci Rep; 2016 Dec; 6():37532. PubMed ID: 27905468
[TBL] [Abstract][Full Text] [Related]
8. Dissociation Process of a MDM2/p53 Complex Investigated by Parallel Cascade Selection Molecular Dynamics and the Markov State Model.
Tran DP; Kitao A
J Phys Chem B; 2019 Mar; 123(11):2469-2478. PubMed ID: 30645121
[TBL] [Abstract][Full Text] [Related]
9. Bridging Microscopic and Macroscopic Mechanisms of p53-MDM2 Binding with Kinetic Network Models.
Zhou G; Pantelopulos GA; Mukherjee S; Voelz VA
Biophys J; 2017 Aug; 113(4):785-793. PubMed ID: 28834715
[TBL] [Abstract][Full Text] [Related]
10. Conformational changes of the p53-binding cleft of MDM2 revealed by molecular dynamics simulations.
Espinoza-Fonseca LM; Trujillo-Ferrara JG
Biopolymers; 2006 Nov; 83(4):365-73. PubMed ID: 16817233
[TBL] [Abstract][Full Text] [Related]
11. Multiple peptide conformations give rise to similar binding affinities: molecular simulations of p53-MDM2.
Dastidar SG; Lane DP; Verma CS
J Am Chem Soc; 2008 Oct; 130(41):13514-5. PubMed ID: 18800837
[TBL] [Abstract][Full Text] [Related]
12. Solution-State Preorganization of Cyclic β-Hairpin Ligands Determines Binding Mechanism and Affinities for MDM2.
Ge Y; Zhang S; Erdelyi M; Voelz VA
J Chem Inf Model; 2021 May; 61(5):2353-2367. PubMed ID: 33905247
[TBL] [Abstract][Full Text] [Related]
13. Modulation of p53 binding to MDM2: computational studies reveal important roles of Tyr100.
Dastidar SG; Lane DP; Verma CS
BMC Bioinformatics; 2009 Dec; 10 Suppl 15(Suppl 15):S6. PubMed ID: 19958516
[TBL] [Abstract][Full Text] [Related]
14. Direct observations of conformational distributions of intrinsically disordered p53 peptides using UV Raman and explicit solvent simulations.
Xiong K; Zwier MC; Myshakina NS; Burger VM; Asher SA; Chong LT
J Phys Chem A; 2011 Sep; 115(34):9520-7. PubMed ID: 21528875
[TBL] [Abstract][Full Text] [Related]
15. Binding Ensembles of
Lang L; Perez A
Molecules; 2021 Jan; 26(1):. PubMed ID: 33401765
[TBL] [Abstract][Full Text] [Related]
16. Chemical states of the N-terminal "lid" of MDM2 regulate p53 binding: simulations reveal complexities of modulation.
Dastidar SG; Raghunathan D; Nicholson J; Hupp TR; Lane DP; Verma CS
Cell Cycle; 2011 Jan; 10(1):82-9. PubMed ID: 21191186
[TBL] [Abstract][Full Text] [Related]
17. Simulation of MDM2 N-terminal domain conformational lability in the presence of imidazoline based inhibitors of MDM2-p53 protein-protein interaction.
Gureev M; Novikova D; Grigoreva T; Vorona S; Garabadzhiu A; Tribulovich V
J Comput Aided Mol Des; 2020 Jan; 34(1):55-70. PubMed ID: 31781989
[TBL] [Abstract][Full Text] [Related]
18. Identification of antipsychotic drug fluspirilene as a potential p53-MDM2 inhibitor: a combined computational and experimental study.
Patil SP; Pacitti MF; Gilroy KS; Ruggiero JC; Griffin JD; Butera JJ; Notarfrancesco JM; Tran S; Stoddart JW
J Comput Aided Mol Des; 2015 Feb; 29(2):155-63. PubMed ID: 25377899
[TBL] [Abstract][Full Text] [Related]
19. Impact of Ser17 Phosphorylation on the Conformational Dynamics of the Oncoprotein MDM2.
Bueren-Calabuig JA; Michel J
Biochemistry; 2016 May; 55(17):2500-9. PubMed ID: 27050388
[TBL] [Abstract][Full Text] [Related]
20. Binding Kinetics of the Intrinsically Disordered p53 Family Transactivation Domains and MDM2.
Åberg E; Karlsson OA; Andersson E; Jemth P
J Phys Chem B; 2018 Jul; 122(27):6899-6905. PubMed ID: 29878773
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
