These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

355 related articles for article (PubMed ID: 27548565)

  • 21. Recent Development of Small Molecule Glutaminase Inhibitors.
    Song M; Kim SH; Im CY; Hwang HJ
    Curr Top Med Chem; 2018; 18(6):432-443. PubMed ID: 29793408
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Identification and optimization of hydrazone-gallate derivatives as specific inhibitors of DNA methyltransferase 3A.
    Erdmann A; Menon Y; Gros C; Masson V; Aussagues Y; Ausseil F; Novosad N; Schambel P; Baltas M; Arimondo PB
    Future Med Chem; 2016; 8(4):373-80. PubMed ID: 26976348
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Small molecule control of chromatin remodeling.
    Finley A; Copeland RA
    Chem Biol; 2014 Sep; 21(9):1196-210. PubMed ID: 25237863
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Targeting histone methylation for cancer therapy: enzymes, inhibitors, biological activity and perspectives.
    Song Y; Wu F; Wu J
    J Hematol Oncol; 2016 Jun; 9(1):49. PubMed ID: 27316347
    [TBL] [Abstract][Full Text] [Related]  

  • 25. [Histone methyltransferases: a new class of therapeutic targets in cancer treatment?].
    Chaib H; Prébet T; Vey N; Collette Y
    Med Sci (Paris); 2011; 27(8-9):725-32. PubMed ID: 21880260
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Design, synthesis and anti leukemia cells proliferation activities of pyrimidylaminoquinoline derivatives as DOT1L inhibitors.
    Zhang L; Chen Y; Liu N; Li L; Xiao S; Li X; Chen K; Luo C; Chen S; Chen H
    Bioorg Chem; 2018 Oct; 80():649-654. PubMed ID: 30059890
    [TBL] [Abstract][Full Text] [Related]  

  • 27. Recent progress in the discovery of small-molecule inhibitors of the HMT EZH2 for the treatment of cancer.
    Verma SK; Knight SD
    Future Med Chem; 2013 Sep; 5(14):1661-70. PubMed ID: 24047271
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Advances at the intersection of chemical biology and medicinal chemistry.
    Tavassoli A
    Future Med Chem; 2015; 7(16):2089-90. PubMed ID: 26571116
    [No Abstract]   [Full Text] [Related]  

  • 29. Advancing the kinase field: new targets and second generation inhibitors.
    Laufer S; Bajorath J
    J Med Chem; 2015 Jan; 58(1):1. PubMed ID: 25490234
    [No Abstract]   [Full Text] [Related]  

  • 30. Inhibitor scaffold for the histone lysine demethylase KDM4C (JMJD2C).
    Leurs U; Clausen RP; Kristensen JL; Lohse B
    Bioorg Med Chem Lett; 2012 Sep; 22(18):5811-3. PubMed ID: 22917519
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Optimization of High-Throughput Methyltransferase Assays for the Discovery of Small Molecule Inhibitors.
    Dong G; Yasgar A; Peterson DL; Zakharov A; Talley D; Cheng KC; Jadhav A; Simeonov A; Huang R
    ACS Comb Sci; 2020 Aug; 22(8):422-432. PubMed ID: 32525297
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Repositioning of Difluorinated Propanediones as Inhibitors of Histone Methyltransferases and their Biological Evaluation in Human Leukemic Cell Lines.
    Pal T; Sharda A; Khade B; Ramaa CS; Gupta S
    Anticancer Agents Med Chem; 2018; 18(13):1892-1899. PubMed ID: 29623853
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Identification of novel inhibitors of DNA methylation by screening of a chemical library.
    Ceccaldi A; Rajavelu A; Ragozin S; Sénamaud-Beaufort C; Bashtrykov P; Testa N; Dali-Ali H; Maulay-Bailly C; Amand S; Guianvarc'h D; Jeltsch A; Arimondo PB
    ACS Chem Biol; 2013 Mar; 8(3):543-8. PubMed ID: 23294304
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Discovery and Evaluation of PRL Trimer Disruptors for Novel Anticancer Agents.
    Bai Y; Yu ZH; Zhang ZY
    Methods Mol Biol; 2016; 1447():121-38. PubMed ID: 27514804
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Structure-Activity Relationship Studies on (R)-PFI-2 Analogues as Inhibitors of Histone Lysine Methyltransferase SETD7.
    Lenstra DC; Damen E; Leenders RGG; Blaauw RH; Rutjes FPJT; Wegert A; Mecinović J
    ChemMedChem; 2018 Jul; 13(14):1405-1413. PubMed ID: 29869845
    [TBL] [Abstract][Full Text] [Related]  

  • 36. New small molecule inhibitors of histone methyl transferase DOT1L with a nitrile as a non-traditional replacement for heavy halogen atoms.
    Spurr SS; Bayle ED; Yu W; Li F; Tempel W; Vedadi M; Schapira M; Fish PV
    Bioorg Med Chem Lett; 2016 Sep; 26(18):4518-4522. PubMed ID: 27485386
    [TBL] [Abstract][Full Text] [Related]  

  • 37. Targeting the production of oncogenic microRNAs with multimodal synthetic small molecules.
    Vo DD; Staedel C; Zehnacker L; Benhida R; Darfeuille F; Duca M
    ACS Chem Biol; 2014 Mar; 9(3):711-21. PubMed ID: 24359019
    [TBL] [Abstract][Full Text] [Related]  

  • 38. Drugging histone methyltransferases in cancer.
    Richart L; Margueron R
    Curr Opin Chem Biol; 2020 Jun; 56():51-62. PubMed ID: 31981999
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Small-molecule inhibitors of the MDM2-p53 protein-protein interaction (MDM2 Inhibitors) in clinical trials for cancer treatment.
    Zhao Y; Aguilar A; Bernard D; Wang S
    J Med Chem; 2015 Feb; 58(3):1038-52. PubMed ID: 25396320
    [TBL] [Abstract][Full Text] [Related]  

  • 40. Substituted purine and 7-deazapurine compounds as modulators of epigenetic enzymes: a patent evaluation (WO2012075381).
    Lipka DB; Kuck D; Kliem C; Gerhauser C
    Expert Opin Ther Pat; 2013 Apr; 23(4):537-43. PubMed ID: 23448241
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 18.