BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

547 related articles for article (PubMed ID: 27551732)

  • 1. Linker Flexibility Facilitates Module Exchange in Fungal Hybrid PKS-NRPS Engineering.
    Nielsen ML; Isbrandt T; Petersen LM; Mortensen UH; Andersen MR; Hoof JB; Larsen TO
    PLoS One; 2016; 11(8):e0161199. PubMed ID: 27551732
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Genus level analysis of PKS-NRPS and NRPS-PKS hybrids reveals their origin in Aspergilli.
    Theobald S; Vesth TC; Andersen MR
    BMC Genomics; 2019 Nov; 20(1):847. PubMed ID: 31722662
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Evolutionary imprint of catalytic domains in fungal PKS-NRPS hybrids.
    Boettger D; Bergmann H; Kuehn B; Shelest E; Hertweck C
    Chembiochem; 2012 Nov; 13(16):2363-73. PubMed ID: 23023987
    [TBL] [Abstract][Full Text] [Related]  

  • 4. The biosynthetic gene cluster for the antitumor drug bleomycin from Streptomyces verticillus ATCC15003 supporting functional interactions between nonribosomal peptide synthetases and a polyketide synthase.
    Du L; Sánchez C; Chen M; Edwards DJ; Shen B
    Chem Biol; 2000 Aug; 7(8):623-42. PubMed ID: 11048953
    [TBL] [Abstract][Full Text] [Related]  

  • 5. ClusterCAD 2.0: an updated computational platform for chimeric type I polyketide synthase and nonribosomal peptide synthetase design.
    Tao XB; LaFrance S; Xing Y; Nava AA; Martin HG; Keasling JD; Backman TWH
    Nucleic Acids Res; 2023 Jan; 51(D1):D532-D538. PubMed ID: 36416273
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Combinatorialization of fungal polyketide synthase-peptide synthetase hybrid proteins.
    Kakule TB; Lin Z; Schmidt EW
    J Am Chem Soc; 2014 Dec; 136(51):17882-90. PubMed ID: 25436464
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Hybrid peptide-polyketide natural products: biosynthesis and prospects toward engineering novel molecules.
    Du L; Sánchez C; Shen B
    Metab Eng; 2001 Jan; 3(1):78-95. PubMed ID: 11162234
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Biosynthesis of the mycotoxin tenuazonic acid by a fungal NRPS-PKS hybrid enzyme.
    Yun CS; Motoyama T; Osada H
    Nat Commun; 2015 Oct; 6():8758. PubMed ID: 26503170
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Genomics-driven discovery of PKS-NRPS hybrid metabolites from Aspergillus nidulans.
    Bergmann S; Schümann J; Scherlach K; Lange C; Brakhage AA; Hertweck C
    Nat Chem Biol; 2007 Apr; 3(4):213-7. PubMed ID: 17369821
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Identification and engineering of the cytochalasin gene cluster from Aspergillus clavatus NRRL 1.
    Qiao K; Chooi YH; Tang Y
    Metab Eng; 2011 Nov; 13(6):723-32. PubMed ID: 21983160
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Biosynthesis of secondary metabolites in the rice blast fungus Magnaporthe grisea: the role of hybrid PKS-NRPS in pathogenicity.
    Collemare J; Billard A; Böhnert HU; Lebrun MH
    Mycol Res; 2008 Feb; 112(Pt 2):207-15. PubMed ID: 18272356
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Biosynthesis of hybrid peptide-polyketide natural products.
    Du L; Shen B
    Curr Opin Drug Discov Devel; 2001 Mar; 4(2):215-28. PubMed ID: 11378961
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Identification of a novel polyketide synthase-nonribosomal peptide synthetase (PKS-NRPS) gene required for the biosynthesis of cyclopiazonic acid in Aspergillus oryzae.
    Tokuoka M; Seshime Y; Fujii I; Kitamoto K; Takahashi T; Koyama Y
    Fungal Genet Biol; 2008 Dec; 45(12):1608-15. PubMed ID: 18854220
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Analysis of intact and dissected fungal polyketide synthase-nonribosomal peptide synthetase in vitro and in Saccharomyces cerevisiae.
    Xu W; Cai X; Jung ME; Tang Y
    J Am Chem Soc; 2010 Oct; 132(39):13604-7. PubMed ID: 20828130
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Phylogenetically diverse cultivable fungal community and polyketide synthase (PKS), non-ribosomal peptide synthase (NRPS) genes associated with the South China Sea sponges.
    Zhou K; Zhang X; Zhang F; Li Z
    Microb Ecol; 2011 Oct; 62(3):644-54. PubMed ID: 21519913
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Quick guide to polyketide synthase and nonribosomal synthetase genes in Fusarium.
    Hansen FT; Sørensen JL; Giese H; Sondergaard TE; Frandsen RJ
    Int J Food Microbiol; 2012 Apr; 155(3):128-36. PubMed ID: 22377171
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Non-ribosomal peptide synthetases: Identifying the cryptic gene clusters and decoding the natural product.
    Singh M; Chaudhary S; Sareen D
    J Biosci; 2017 Mar; 42(1):175-187. PubMed ID: 28229977
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Protein-protein interactions in polyketide synthase-nonribosomal peptide synthetase hybrid assembly lines.
    Miyanaga A; Kudo F; Eguchi T
    Nat Prod Rep; 2018 Nov; 35(11):1185-1209. PubMed ID: 30074030
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Phylogenetic study of polyketide synthases and nonribosomal peptide synthetases involved in the biosynthesis of mycotoxins.
    Gallo A; Ferrara M; Perrone G
    Toxins (Basel); 2013 Apr; 5(4):717-42. PubMed ID: 23604065
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Acurin A, a novel hybrid compound, biosynthesized by individually translated PKS- and NRPS-encoding genes in Aspergillus aculeatus.
    Wolff PB; Nielsen ML; Slot JC; Andersen LN; Petersen LM; Isbrandt T; Holm DK; Mortensen UH; Nødvig CS; Larsen TO; Hoof JB
    Fungal Genet Biol; 2020 Jun; 139():103378. PubMed ID: 32234543
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 28.