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3. Mutations in the ubiquitin-binding domain of OPTN/optineurin interfere with autophagy-mediated degradation of misfolded proteins by a dominant-negative mechanism. Shen WC; Li HY; Chen GC; Chern Y; Tu PH Autophagy; 2015 Apr; 11(4):685-700. PubMed ID: 25484089 [TBL] [Abstract][Full Text] [Related]
4. Structural insights into the ubiquitin recognition by OPTN (optineurin) and its regulation by TBK1-mediated phosphorylation. Li F; Xu D; Wang Y; Zhou Z; Liu J; Hu S; Gong Y; Yuan J; Pan L Autophagy; 2018; 14(1):66-79. PubMed ID: 29394115 [TBL] [Abstract][Full Text] [Related]
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6. [Identification of a new causative gene of amyotrophic lateral sclerosis; optineurin]. Maruyama H Rinsho Shinkeigaku; 2012; 52(1):1-5. PubMed ID: 22260971 [TBL] [Abstract][Full Text] [Related]
7. Oligogenic inheritance of optineurin (OPTN) and C9ORF72 mutations in ALS highlights localisation of OPTN in the TDP-43-negative inclusions of C9ORF72-ALS. Bury JJ; Highley JR; Cooper-Knock J; Goodall EF; Higginbottom A; McDermott CJ; Ince PG; Shaw PJ; Kirby J Neuropathology; 2016 Apr; 36(2):125-34. PubMed ID: 26303227 [TBL] [Abstract][Full Text] [Related]
8. Evidence of a link between ubiquilin 2 and optineurin in amyotrophic lateral sclerosis. Osaka M; Ito D; Yagi T; Nihei Y; Suzuki N Hum Mol Genet; 2015 Mar; 24(6):1617-29. PubMed ID: 25398946 [TBL] [Abstract][Full Text] [Related]
9. Optineurin suppression causes neuronal cell death via NF-κB pathway. Akizuki M; Yamashita H; Uemura K; Maruyama H; Kawakami H; Ito H; Takahashi R J Neurochem; 2013 Sep; 126(6):699-704. PubMed ID: 23721573 [TBL] [Abstract][Full Text] [Related]
10. Identification of optineurin as an interleukin-1 receptor-associated kinase 1-binding protein and its role in regulation of MyD88-dependent signaling. Tanishima M; Takashima S; Honda A; Yasuda D; Tanikawa T; Ishii S; MaruYama T J Biol Chem; 2017 Oct; 292(42):17250-17257. PubMed ID: 28882891 [TBL] [Abstract][Full Text] [Related]
12. Dynamic recruitment and activation of ALS-associated TBK1 with its target optineurin are required for efficient mitophagy. Moore AS; Holzbaur EL Proc Natl Acad Sci U S A; 2016 Jun; 113(24):E3349-58. PubMed ID: 27247382 [TBL] [Abstract][Full Text] [Related]
13. Functional analysis of optineurin and some of its disease-associated mutants. Bansal M; Swarup G; Balasubramanian D IUBMB Life; 2015 Feb; 67(2):120-8. PubMed ID: 25855473 [TBL] [Abstract][Full Text] [Related]
14. Nuclear factor κ B expression in patients with sporadic amyotrophic lateral sclerosis and hereditary amyotrophic lateral sclerosis with optineurin mutations. Sako W; Ito H; Yoshida M; Koizumi H; Kamada M; Fujita K; Hashizume Y; Izumi Y; Kaji R Clin Neuropathol; 2012; 31(6):418-23. PubMed ID: 22762947 [TBL] [Abstract][Full Text] [Related]
15. Altered Functions and Interactions of Glaucoma-Associated Mutants of Optineurin. Swarup G; Sayyad Z Front Immunol; 2018; 9():1287. PubMed ID: 29951055 [TBL] [Abstract][Full Text] [Related]
16. ALS-Associated E478G Mutation in Human OPTN (Optineurin) Promotes Inflammation and Induces Neuronal Cell Death. Liu Z; Li H; Hong C; Chen M; Yue T; Chen C; Wang Z; You Q; Li C; Weng Q; Xie H; Hu R Front Immunol; 2018; 9():2647. PubMed ID: 30519240 [TBL] [Abstract][Full Text] [Related]
17. A novel optineurin truncating mutation and three glaucoma-associated missense variants in patients with familial amyotrophic lateral sclerosis in Germany. Weishaupt JH; Waibel S; Birve A; Volk AE; Mayer B; Meyer T; Ludolph AC; Andersen PM Neurobiol Aging; 2013 May; 34(5):1516.e9-15. PubMed ID: 23062601 [TBL] [Abstract][Full Text] [Related]
18. Optineurin Deficiency and Insufficiency Lead to Higher Microglial TDP-43 Protein Levels. Prtenjaca N; Rob M; Alam MS; Markovinovic A; Stuani C; Buratti E; Munitic I Int J Mol Sci; 2022 Jun; 23(12):. PubMed ID: 35743272 [TBL] [Abstract][Full Text] [Related]
19. Cellular Functions of Optineurin in Health and Disease. Slowicka K; Vereecke L; van Loo G Trends Immunol; 2016 Sep; 37(9):621-633. PubMed ID: 27480243 [TBL] [Abstract][Full Text] [Related]