These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

109 related articles for article (PubMed ID: 27554445)

  • 1. Characterization of 3,3-dimethyl substituted N-aryl piperidines as potent microsomal prostaglandin E synthase-1 inhibitors.
    Kuklish SL; Antonysamy S; Bhattachar SN; Chandrasekhar S; Fisher MJ; Fretland AJ; Gooding K; Harvey A; Hughes NE; Luz JG; Manninen PR; McGee JE; Navarro A; Norman BH; Partridge KM; Quimby SJ; Schiffler MA; Sloan AV; Warshawsky AM; York JS; Yu XP
    Bioorg Med Chem Lett; 2016 Oct; 26(19):4824-4828. PubMed ID: 27554445
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Discovery and characterization of [(cyclopentyl)ethyl]benzoic acid inhibitors of microsomal prostaglandin E synthase-1.
    Partridge KM; Antonysamy S; Bhattachar SN; Chandrasekhar S; Fisher MJ; Fretland A; Gooding K; Harvey A; Hughes NE; Kuklish SL; Luz JG; Manninen PR; McGee JE; Mudra DR; Navarro A; Norman BH; Quimby SJ; Schiffler MA; Sloan AV; Warshawsky AM; Weller JM; York JS; Yu XP
    Bioorg Med Chem Lett; 2017 Mar; 27(6):1478-1483. PubMed ID: 28190634
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Tricyclic 4,4-dimethyl-3,4-dihydrochromeno[3,4-d]imidazole derivatives as microsomal prostaglandin E
    Muthukaman N; Tambe M; Shaikh M; Pisal D; Deshmukh S; Tondlekar S; Sarode N; Narayana L; Gajera JM; Kattige VG; Honnegowda S; Karande V; Kulkarni A; Behera D; Jadhav SB; Gudi GS; Khairatkar-Joshi N; Gharat LA
    Bioorg Med Chem Lett; 2017 Jun; 27(11):2594-2601. PubMed ID: 28400234
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Biological characterization of new inhibitors of microsomal PGE synthase-1 in preclinical models of inflammation and vascular tone.
    Larsson K; Steinmetz J; Bergqvist F; Arefin S; Spahiu L; Wannberg J; Pawelzik SC; Morgenstern R; Stenberg P; Kublickiene K; Korotkova M; Jakobsson PJ
    Br J Pharmacol; 2019 Dec; 176(24):4625-4638. PubMed ID: 31404942
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Discovery of 2-((2-chloro-6-fluorophenyl)amino)-N-(3-fluoro-5-(trifluoromethyl)phenyl)-1-methyl-7,8-dihydro-1H-[1,4]dioxino[2',3':3,4]benzo[1,2-d]imidazole-5-carboxamide as potent, selective and efficacious microsomal prostaglandin E
    Muthukaman N; Deshmukh S; Sarode N; Tondlekar S; Tambe M; Pisal D; Shaikh M; Kattige VG; Honnegowda S; Karande V; Kulkarni A; Jadhav SB; Mahat MYA; Gudi GS; Khairatkar-Joshi N; Gharat LA
    Bioorg Med Chem Lett; 2016 Dec; 26(24):5977-5984. PubMed ID: 27865703
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Discovery of furan and dihydrofuran-fused tricyclic benzo[d]imidazole derivatives as potent and orally efficacious microsomal prostaglandin E synthase-1 (mPGES-1) inhibitors: Part-1.
    Muthukaman N; Tambe M; Deshmukh S; Pisal D; Tondlekar S; Shaikh M; Sarode N; Kattige VG; Pisat M; Sawant P; Honnegowda S; Karande V; Kulkarni A; Behera D; Jadhav SB; Sangana RR; Gudi GS; Khairatkar-Joshi N; Gharat LA
    Bioorg Med Chem Lett; 2017 Dec; 27(23):5131-5138. PubMed ID: 29100801
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Alleviating CYP and hERG liabilities by structure optimization of dihydrofuran-fused tricyclic benzo[d]imidazole series - Potent, selective and orally efficacious microsomal prostaglandin E synthase-1 (mPGES-1) inhibitors: Part-2.
    Muthukaman N; Deshmukh S; Tambe M; Pisal D; Tondlekar S; Shaikh M; Sarode N; Kattige VG; Sawant P; Pisat M; Karande V; Honnegowda S; Kulkarni A; Behera D; Jadhav SB; Sangana RR; Gudi GS; Khairatkar-Joshi N; Gharat LA
    Bioorg Med Chem Lett; 2018 Apr; 28(7):1211-1218. PubMed ID: 29519738
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Development of 2-aryl substituted quinazolin-4(3H)-one, pyrido[4,3-d]pyrimidin-4(3H)-one and pyrido[2,3-d]pyrimidin-4(3H)-one derivatives as microsomal prostaglandin E(2) synthase-1 inhibitors.
    Banerjee A; Pawar MY; Patil S; Yadav PS; Kadam PA; Kattige VG; Deshpande DS; Pednekar PV; Pisat MK; Gharat LA
    Bioorg Med Chem Lett; 2014 Oct; 24(20):4838-44. PubMed ID: 25260492
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Perspective of microsomal prostaglandin E2 synthase-1 as drug target in inflammation-related disorders.
    Koeberle A; Werz O
    Biochem Pharmacol; 2015 Nov; 98(1):1-15. PubMed ID: 26123522
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Identification of novel microsomal prostaglandin E
    Lauro G; Manfra M; Pedatella S; Fischer K; Cantone V; Terracciano S; Bertamino A; Ostacolo C; Gomez-Monterrey I; De Nisco M; Riccio R; Novellino E; Werz O; Campiglia P; Bifulco G
    Eur J Med Chem; 2017 Jan; 125():278-287. PubMed ID: 27688183
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Discovery of N-amido-phenylsulfonamide derivatives as novel microsomal prostaglandin E
    Kim M; Kim G; Kang M; Ko D; Nam Y; Moon CS; Kang HM; Shin JS; Werz O; Lee KT; Lee JY
    Bioorg Med Chem Lett; 2021 Jun; 41():127992. PubMed ID: 33775835
    [TBL] [Abstract][Full Text] [Related]  

  • 12. A Multi-step Virtual Screening Protocol for the Identification of Novel Non-acidic Microsomal Prostaglandin E
    Shekfeh S; Çalışkan B; Fischer K; Yalçın T; Garscha U; Werz O; Banoglu E
    ChemMedChem; 2019 Jan; 14(2):273-281. PubMed ID: 30537167
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Discovery of highly potent microsomal prostaglandin e2 synthase 1 inhibitors using the active conformation structural model and virtual screen.
    He S; Li C; Liu Y; Lai L
    J Med Chem; 2013 Apr; 56(8):3296-309. PubMed ID: 23527738
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Microsomal prostaglandin E
    Psarra A; Nikolaou A; Kokotou MG; Limnios D; Kokotos G
    Expert Opin Ther Pat; 2017 Sep; 27(9):1047-1059. PubMed ID: 28627961
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Discovery and Characterization of 2-Acylaminoimidazole Microsomal Prostaglandin E Synthase-1 Inhibitors.
    Schiffler MA; Antonysamy S; Bhattachar SN; Campanale KM; Chandrasekhar S; Condon B; Desai PV; Fisher MJ; Groshong C; Harvey A; Hickey MJ; Hughes NE; Jones SA; Kim EJ; Kuklish SL; Luz JG; Norman BH; Rathmell RE; Rizzo JR; Seng TW; Thibodeaux SJ; Woods TA; York JS; Yu XP
    J Med Chem; 2016 Jan; 59(1):194-205. PubMed ID: 26653180
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Distinction of microsomal prostaglandin E synthase-1 (mPGES-1) inhibition from cyclooxygenase-2 inhibition in cells using a novel, selective mPGES-1 inhibitor.
    Mbalaviele G; Pauley AM; Shaffer AF; Zweifel BS; Mathialagan S; Mnich SJ; Nemirovskiy OV; Carter J; Gierse JK; Wang JL; Vazquez ML; Moore WM; Masferrer JL
    Biochem Pharmacol; 2010 May; 79(10):1445-54. PubMed ID: 20067770
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Arylpyrrolizines as inhibitors of microsomal prostaglandin E2 synthase-1 (mPGES-1) or as dual inhibitors of mPGES-1 and 5-lipoxygenase (5-LOX).
    Liedtke AJ; Keck PR; Lehmann F; Koeberle A; Werz O; Laufer SA
    J Med Chem; 2009 Aug; 52(15):4968-72. PubMed ID: 19719242
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Design and Development of Microsomal Prostaglandin E2 Synthase-1 Inhibitors: Challenges and Future Directions.
    Koeberle A; Laufer SA; Werz O
    J Med Chem; 2016 Jul; 59(13):5970-86. PubMed ID: 26791385
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Regulation of prostaglandin E synthases: effects of siRNA-mediated inhibition of microsomal prostaglandin E synthase-1.
    Båge T; Modéer T; Kawakami T; Quezada HC; Yucel-Lindberg T
    Biochim Biophys Acta; 2007 Oct; 1773(10):1589-98. PubMed ID: 17707523
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Characterization of microsomal prostaglandin E synthase 1 inhibitors.
    Korotkova M; Jakobsson PJ
    Basic Clin Pharmacol Toxicol; 2014 Jan; 114(1):64-9. PubMed ID: 24138533
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 6.