These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.
5. Structural alterations based on naproxen scaffold: Synthesis, evaluation of antitumor activity and COX-2 inhibition, and molecular docking. El-Husseiny WM; El-Sayed MA; Abdel-Aziz NI; El-Azab AS; Asiri YA; Abdel-Aziz AA Eur J Med Chem; 2018 Oct; 158():134-143. PubMed ID: 30216848 [TBL] [Abstract][Full Text] [Related]
6. A novel naproxen derivative capable of displaying anti-cancer and anti-migratory properties against human breast cancer cells. Deb J; Majumder J; Bhattacharyya S; Jana SS BMC Cancer; 2014 Aug; 14():567. PubMed ID: 25098498 [TBL] [Abstract][Full Text] [Related]
7. Synthesis, Cyclooxygenase-2 Inhibition, Anti-inflammatory Evaluation and Docking Study of Substituted-N-(3,4,5-trimethoxyphenyl)-benzo[d]oxazole Derivatives. Kaur A; Wakode S; Pathak DP; Sharma V; Shakya AK Med Chem; 2018; 14(7):660-673. PubMed ID: 29564981 [TBL] [Abstract][Full Text] [Related]
8. Design, synthesis, modeling studies and biological evaluation of pyrazole derivatives linked to oxime and nitrate moieties as nitric oxide donor selective COX-2 and aromatase inhibitors with dual anti-inflammatory and anti-neoplastic activities. A A Fadaly W; A M M Elshaier Y; T M Nemr M; R A Abdellatif K Bioorg Chem; 2023 May; 134():106428. PubMed ID: 36893546 [TBL] [Abstract][Full Text] [Related]
9. Enhanced chemopreventive effects of a hydrogen sulfide-releasing anti-inflammatory drug (ATB-346) in experimental colorectal cancer. Elsheikh W; Blackler RW; Flannigan KL; Wallace JL Nitric Oxide; 2014 Sep; 41():131-7. PubMed ID: 24747869 [TBL] [Abstract][Full Text] [Related]
10. Discovery of small molecule acting as multitarget inhibitor of colorectal cancer by simultaneous blocking of the key COX-2, 5-LOX and PIM-1 kinase enzymes. El-Miligy MMM; Al-Kubeisi AK; El-Zemity SR; Nassra RA; Abu-Serie MM; Hazzaa AA Bioorg Chem; 2021 Oct; 115():105171. PubMed ID: 34303896 [TBL] [Abstract][Full Text] [Related]
11. Design and synthesis of novel (S)-Naproxen hydrazide-hydrazones as potent VEGFR-2 inhibitors and their evaluation in vitro/in vivo breast cancer models. Han Mİ; Atalay P; Tunç CÜ; Ünal G; Dayan S; Aydın Ö; Küçükgüzel ŞG Bioorg Med Chem; 2021 May; 37():116097. PubMed ID: 33743356 [TBL] [Abstract][Full Text] [Related]
12. A novel sulindac derivative that does not inhibit cyclooxygenases but potently inhibits colon tumor cell growth and induces apoptosis with antitumor activity. Piazza GA; Keeton AB; Tinsley HN; Gary BD; Whitt JD; Mathew B; Thaiparambil J; Coward L; Gorman G; Li Y; Sani B; Hobrath JV; Maxuitenko YY; Reynolds RC Cancer Prev Res (Phila); 2009 Jun; 2(6):572-80. PubMed ID: 19470791 [TBL] [Abstract][Full Text] [Related]
13. Hydrogen sulfide-releasing naproxen suppresses colon cancer cell growth and inhibits NF-κB signaling. Kodela R; Nath N; Chattopadhyay M; Nesbitt DE; Velázquez-Martínez CA; Kashfi K Drug Des Devel Ther; 2015; 9():4873-82. PubMed ID: 26346117 [TBL] [Abstract][Full Text] [Related]
14. Synthesis, molecular modeling, in vivo study and anticancer activity against prostate cancer of (+) (S)-naproxen derivatives. Birgül K; Yıldırım Y; Karasulu HY; Karasulu E; Uba AI; Yelekçi K; Bekçi H; Cumaoğlu A; Kabasakal L; Yılmaz Ö; Küçükgüzel ŞG Eur J Med Chem; 2020 Dec; 208():112841. PubMed ID: 32998089 [TBL] [Abstract][Full Text] [Related]
15. Biochemical and pharmacological profile of a tetrasubstituted furanone as a highly selective COX-2 inhibitor. Riendeau D; Percival MD; Boyce S; Brideau C; Charleson S; Cromlish W; Ethier D; Evans J; Falgueyret JP; Ford-Hutchinson AW; Gordon R; Greig G; Gresser M; Guay J; Kargman S; Léger S; Mancini JA; O'Neill G; Ouellet M; Rodger IW; Thérien M; Wang Z; Webb JK; Wong E; Chan CC Br J Pharmacol; 1997 May; 121(1):105-17. PubMed ID: 9146894 [TBL] [Abstract][Full Text] [Related]
16. Identification of Novel Cyclooxygenase-1 Selective Inhibitors of Thiadiazole-Based Scaffold as Potent Anti-Inflammatory Agents with Safety Gastric and Cytotoxic Profile. Haroun M; Fesatidou M; Petrou A; Tratrat C; Zagaliotis P; Gavalas A; Venugopala KN; Kochkar H; Emeka PM; Younis NS; Elmaghraby DA; Almostafa MM; Chohan MS; Vizirianakis IS; Papadimitriou-Tsantarliotou A; Geronikaki A Molecules; 2023 Apr; 28(8):. PubMed ID: 37110650 [TBL] [Abstract][Full Text] [Related]