287 related articles for article (PubMed ID: 27559927)
1. Shelterin Telomere Protection Protein 1 Reduction Causes Telomere Attrition and Cellular Senescence via Sirtuin 1 Deacetylase in Chronic Obstructive Pulmonary Disease.
Ahmad T; Sundar IK; Tormos AM; Lerner CA; Gerloff J; Yao H; Rahman I
Am J Respir Cell Mol Biol; 2017 Jan; 56(1):38-49. PubMed ID: 27559927
[TBL] [Abstract][Full Text] [Related]
2. Regulation of lung epithelial cell senescence in smoking-induced COPD/emphysema by microR-125a-5p via Sp1 mediation of SIRT1/HIF-1a.
Wu H; Ma H; Wang L; Zhang H; Lu L; Xiao T; Cheng C; Wang P; Yang Y; Wu M; Wang S; Zhang J; Liu Q
Int J Biol Sci; 2022; 18(2):661-674. PubMed ID: 35002516
[TBL] [Abstract][Full Text] [Related]
3. SIRT1 protects against emphysema via FOXO3-mediated reduction of premature senescence in mice.
Yao H; Chung S; Hwang JW; Rajendrasozhan S; Sundar IK; Dean DA; McBurney MW; Guarente L; Gu W; Rönty M; Kinnula VL; Rahman I
J Clin Invest; 2012 Jun; 122(6):2032-45. PubMed ID: 22546858
[TBL] [Abstract][Full Text] [Related]
4. FOXO3 Activation Prevents Cellular Senescence in Emphysema Induced by Cigarette Smoke.
Jiang H; Xu Y; Jiang Y; Li Y
COPD; 2023 Dec; 20(1):80-91. PubMed ID: 36656684
[TBL] [Abstract][Full Text] [Related]
5. Genetic ablation of histone deacetylase 2 leads to lung cellular senescence and lymphoid follicle formation in COPD/emphysema.
Sundar IK; Rashid K; Gerloff J; Rangel-Moreno J; Li D; Rahman I
FASEB J; 2018 Sep; 32(9):4955-4971. PubMed ID: 29630406
[TBL] [Abstract][Full Text] [Related]
6. Cigarette smoke-induced autophagy impairment accelerates lung aging, COPD-emphysema exacerbations and pathogenesis.
Vij N; Chandramani-Shivalingappa P; Van Westphal C; Hole R; Bodas M
Am J Physiol Cell Physiol; 2018 Jan; 314(1):C73-C87. PubMed ID: 27413169
[TBL] [Abstract][Full Text] [Related]
7. SIRT1 redresses the imbalance of tissue inhibitor of matrix metalloproteinase-1 and matrix metalloproteinase-9 in the development of mouse emphysema and human COPD.
Yao H; Hwang JW; Sundar IK; Friedman AE; McBurney MW; Guarente L; Gu W; Kinnula VL; Rahman I
Am J Physiol Lung Cell Mol Physiol; 2013 Nov; 305(9):L615-24. PubMed ID: 24039251
[TBL] [Abstract][Full Text] [Related]
8. Club cell-specific telomere protection protein 1 (TPP1) protects against tobacco smoke-induced lung inflammation, xenobiotic metabolic dysregulation, and injurious responses.
Muthumalage T; Goracci C; Rahman I
FASEB Bioadv; 2024 Feb; 6(2):53-71. PubMed ID: 38344410
[TBL] [Abstract][Full Text] [Related]
9. Impaired mitophagy leads to cigarette smoke stress-induced cellular senescence: implications for chronic obstructive pulmonary disease.
Ahmad T; Sundar IK; Lerner CA; Gerloff J; Tormos AM; Yao H; Rahman I
FASEB J; 2015 Jul; 29(7):2912-29. PubMed ID: 25792665
[TBL] [Abstract][Full Text] [Related]
10. Telomere protection by TPP1 is mediated by POT1a and POT1b.
Kibe T; Osawa GA; Keegan CE; de Lange T
Mol Cell Biol; 2010 Feb; 30(4):1059-66. PubMed ID: 19995905
[TBL] [Abstract][Full Text] [Related]
11. In vivo stoichiometry of shelterin components.
Takai KK; Hooper S; Blackwood S; Gandhi R; de Lange T
J Biol Chem; 2010 Jan; 285(2):1457-67. PubMed ID: 19864690
[TBL] [Abstract][Full Text] [Related]
12. Telomere protection by mammalian Pot1 requires interaction with Tpp1.
Hockemeyer D; Palm W; Else T; Daniels JP; Takai KK; Ye JZ; Keegan CE; de Lange T; Hammer GD
Nat Struct Mol Biol; 2007 Aug; 14(8):754-61. PubMed ID: 17632522
[TBL] [Abstract][Full Text] [Related]
13. Genetic Ablation of p16
Sundar IK; Rashid K; Gerloff J; Li D; Rahman I
Am J Respir Cell Mol Biol; 2018 Aug; 59(2):189-199. PubMed ID: 29447461
[TBL] [Abstract][Full Text] [Related]
14. Shelterin proteins and cancer.
Patel TN; Vasan R; Gupta D; Patel J; Trivedi M
Asian Pac J Cancer Prev; 2015; 16(8):3085-90. PubMed ID: 25921101
[TBL] [Abstract][Full Text] [Related]
15. TPP1 is a homologue of ciliate TEBP-beta and interacts with POT1 to recruit telomerase.
Xin H; Liu D; Wan M; Safari A; Kim H; Sun W; O'Connor MS; Songyang Z
Nature; 2007 Feb; 445(7127):559-62. PubMed ID: 17237767
[TBL] [Abstract][Full Text] [Related]
16. TRF2-tethered TIN2 can mediate telomere protection by TPP1/POT1.
Frescas D; de Lange T
Mol Cell Biol; 2014 Apr; 34(7):1349-62. PubMed ID: 24469404
[TBL] [Abstract][Full Text] [Related]
17. Mitoribosomal Deregulation Drives Senescence via TPP1-Mediated Telomere Deprotection.
Min S; Kwon SM; Hong J; Lee YK; Park TJ; Lim SB; Yoon G
Cells; 2022 Jun; 11(13):. PubMed ID: 35805162
[TBL] [Abstract][Full Text] [Related]
18. DNA damage response at telomeres contributes to lung aging and chronic obstructive pulmonary disease.
Birch J; Anderson RK; Correia-Melo C; Jurk D; Hewitt G; Marques FM; Green NJ; Moisey E; Birrell MA; Belvisi MG; Black F; Taylor JJ; Fisher AJ; De Soyza A; Passos JF
Am J Physiol Lung Cell Mol Physiol; 2015 Nov; 309(10):L1124-37. PubMed ID: 26386121
[TBL] [Abstract][Full Text] [Related]
19. Perspectives on translational and therapeutic aspects of SIRT1 in inflammaging and senescence.
Yao H; Rahman I
Biochem Pharmacol; 2012 Nov; 84(10):1332-9. PubMed ID: 22796566
[TBL] [Abstract][Full Text] [Related]
20. Dysfunctional telomeres activate an ATM-ATR-dependent DNA damage response to suppress tumorigenesis.
Guo X; Deng Y; Lin Y; Cosme-Blanco W; Chan S; He H; Yuan G; Brown EJ; Chang S
EMBO J; 2007 Nov; 26(22):4709-19. PubMed ID: 17948054
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
