418 related articles for article (PubMed ID: 27562646)
1. TNIK inhibition abrogates colorectal cancer stemness.
Masuda M; Uno Y; Ohbayashi N; Ohata H; Mimata A; Kukimoto-Niino M; Moriyama H; Kashimoto S; Inoue T; Goto N; Okamoto K; Shirouzu M; Sawa M; Yamada T
Nat Commun; 2016 Aug; 7():12586. PubMed ID: 27562646
[TBL] [Abstract][Full Text] [Related]
2. Traf2- and Nck-interacting kinase is essential for Wnt signaling and colorectal cancer growth.
Shitashige M; Satow R; Jigami T; Aoki K; Honda K; Shibata T; Ono M; Hirohashi S; Yamada T
Cancer Res; 2010 Jun; 70(12):5024-33. PubMed ID: 20530691
[TBL] [Abstract][Full Text] [Related]
3. Therapeutic targets in the Wnt signaling pathway: Feasibility of targeting TNIK in colorectal cancer.
Masuda M; Sawa M; Yamada T
Pharmacol Ther; 2015 Dec; 156():1-9. PubMed ID: 26542362
[TBL] [Abstract][Full Text] [Related]
4. TRIB3 Interacts With β-Catenin and TCF4 to Increase Stem Cell Features of Colorectal Cancer Stem Cells and Tumorigenesis.
Hua F; Shang S; Yang YW; Zhang HZ; Xu TL; Yu JJ; Zhou DD; Cui B; Li K; Lv XX; Zhang XW; Liu SS; Yu JM; Wang F; Zhang C; Huang B; Hu ZW
Gastroenterology; 2019 Feb; 156(3):708-721.e15. PubMed ID: 30365932
[TBL] [Abstract][Full Text] [Related]
5. Emergence of TNIK inhibitors in cancer therapeutics.
Yamada T; Masuda M
Cancer Sci; 2017 May; 108(5):818-823. PubMed ID: 28208209
[TBL] [Abstract][Full Text] [Related]
6. Synergistic inhibition effect of TNIK inhibitor KY-05009 and receptor tyrosine kinase inhibitor dovitinib on IL-6-induced proliferation and Wnt signaling pathway in human multiple myeloma cells.
Lee Y; Jung JI; Park KY; Kim SA; Kim J
Oncotarget; 2017 Jun; 8(25):41091-41101. PubMed ID: 28467797
[TBL] [Abstract][Full Text] [Related]
7. Structural Insight into TNIK Inhibition.
Kukimoto-Niino M; Shirouzu M; Yamada T
Int J Mol Sci; 2022 Oct; 23(21):. PubMed ID: 36361804
[TBL] [Abstract][Full Text] [Related]
8. Targeting the Wnt signaling pathway in colorectal cancer.
Sawa M; Masuda M; Yamada T
Expert Opin Ther Targets; 2016; 20(4):419-29. PubMed ID: 26439805
[TBL] [Abstract][Full Text] [Related]
9. MEK inhibitors activate Wnt signalling and induce stem cell plasticity in colorectal cancer.
Zhan T; Ambrosi G; Wandmacher AM; Rauscher B; Betge J; Rindtorff N; Häussler RS; Hinsenkamp I; Bamberg L; Hessling B; Müller-Decker K; Erdmann G; Burgermeister E; Ebert MP; Boutros M
Nat Commun; 2019 May; 10(1):2197. PubMed ID: 31097693
[TBL] [Abstract][Full Text] [Related]
10. Direct conversion of osteosarcoma to adipocytes by targeting TNIK.
Hirozane T; Masuda M; Sugano T; Sekita T; Goto N; Aoyama T; Sakagami T; Uno Y; Moriyama H; Sawa M; Asano N; Nakamura M; Matsumoto M; Nakayama R; Kondo T; Kawai A; Kobayashi E; Yamada T
JCI Insight; 2021 Feb; 6(3):. PubMed ID: 33400690
[TBL] [Abstract][Full Text] [Related]
11. Jatrorrhizine inhibits mammary carcinoma cells by targeting TNIK mediated Wnt/β-catenin signalling and epithelial-mesenchymal transition (EMT).
Sun Y; Gao X; Wu P; Wink M; Li J; Dian L; Liang Z
Phytomedicine; 2019 Oct; 63():153015. PubMed ID: 31302315
[TBL] [Abstract][Full Text] [Related]
12. The kinase TNIK is an essential activator of Wnt target genes.
Mahmoudi T; Li VS; Ng SS; Taouatas N; Vries RG; Mohammed S; Heck AJ; Clevers H
EMBO J; 2009 Nov; 28(21):3329-40. PubMed ID: 19816403
[TBL] [Abstract][Full Text] [Related]
13. Traf2- and Nck-interacting kinase (TNIK) is involved in the anti-cancer mechanism of dovitinib in human multiple myeloma IM-9 cells.
Chon HJ; Lee Y; Bae KJ; Byun BJ; Kim SA; Kim J
Amino Acids; 2016 Jul; 48(7):1591-9. PubMed ID: 26995282
[TBL] [Abstract][Full Text] [Related]
14. Discovery of 3,4-Dihydrobenzo[
Li Y; Zhang L; Yang R; Qiao Z; Wu M; Huang C; Tian C; Luo X; Yang W; Zhang Y; Li L; Yang S
J Med Chem; 2022 Feb; 65(3):1786-1807. PubMed ID: 34985886
[TBL] [Abstract][Full Text] [Related]
15. Liquidambaric acid inhibits Wnt/β-catenin signaling and colon cancer via targeting TNF receptor-associated factor 2.
Yan R; Zhu H; Huang P; Yang M; Shen M; Pan Y; Zhang C; Zhou X; Li H; Ke X; Zhang W; Hao P; Qu Y
Cell Rep; 2022 Feb; 38(5):110319. PubMed ID: 35108540
[TBL] [Abstract][Full Text] [Related]
16. Scutellaria barbata D. Don inhibits colorectal cancer growth via suppression of Wnt/β-catenin signaling pathway.
Wei LH; Lin JM; Chu JF; Chen HW; Li QY; Peng J
Chin J Integr Med; 2017 Nov; 23(11):858-863. PubMed ID: 29080197
[TBL] [Abstract][Full Text] [Related]
17. A novel aminothiazole KY-05009 with potential to inhibit Traf2- and Nck-interacting kinase (TNIK) attenuates TGF-β1-mediated epithelial-to-mesenchymal transition in human lung adenocarcinoma A549 cells.
Kim J; Moon SH; Kim BT; Chae CH; Lee JY; Kim SH
PLoS One; 2014; 9(10):e110180. PubMed ID: 25337707
[TBL] [Abstract][Full Text] [Related]
18. Chlorquinaldol targets the β-catenin and T-cell factor 4 complex and exerts anti-colorectal cancer activity.
Wang L; Deng K; Gong L; Zhou L; Sayed S; Li H; Sun Q; Su Z; Wang Z; Liu S; Zhu H; Song J; Lu D
Pharmacol Res; 2020 Sep; 159():104955. PubMed ID: 32485279
[TBL] [Abstract][Full Text] [Related]
19. Role of the Rap2/TNIK kinase pathway in regulation of LRP6 stability for Wnt signaling.
Park DS; Seo JH; Hong M; Choi SC
Biochem Biophys Res Commun; 2013 Jun; 436(2):338-43. PubMed ID: 23743195
[TBL] [Abstract][Full Text] [Related]
20. UHRF2 promotes intestinal tumorigenesis through stabilization of TCF4 mediated Wnt/β-catenin signaling.
Li L; Duan Q; Zeng Z; Zhao J; Lu J; Sun J; Zhang J; Siwko S; Wong J; Shi T; Zhang X; Liu M; Chen J; Li D
Int J Cancer; 2020 Oct; 147(8):2239-2252. PubMed ID: 32372448
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
