179 related articles for article (PubMed ID: 27564663)
1. New Concepts in Alpha-1 Antitrypsin Deficiency Disease Mechanisms.
Marciniak SJ; Ordóñez A; Dickens JA; Chambers JE; Patel V; Dominicus CS; Malzer E
Ann Am Thorac Soc; 2016 Aug; 13 Suppl 4():S289-96. PubMed ID: 27564663
[TBL] [Abstract][Full Text] [Related]
2. Accumulation of mutant alpha1-antitrypsin Z in the endoplasmic reticulum activates caspases-4 and -12, NFkappaB, and BAP31 but not the unfolded protein response.
Hidvegi T; Schmidt BZ; Hale P; Perlmutter DH
J Biol Chem; 2005 Nov; 280(47):39002-15. PubMed ID: 16183649
[TBL] [Abstract][Full Text] [Related]
3. Endoplasmic reticulum polymers impair luminal protein mobility and sensitize to cellular stress in alpha1-antitrypsin deficiency.
Ordóñez A; Snapp EL; Tan L; Miranda E; Marciniak SJ; Lomas DA
Hepatology; 2013 May; 57(5):2049-60. PubMed ID: 23197448
[TBL] [Abstract][Full Text] [Related]
4. Activation of endoplasmic reticulum-specific stress responses associated with the conformational disease Z alpha 1-antitrypsin deficiency.
Lawless MW; Greene CM; Mulgrew A; Taggart CC; O'Neill SJ; McElvaney NG
J Immunol; 2004 May; 172(9):5722-6. PubMed ID: 15100318
[TBL] [Abstract][Full Text] [Related]
5. Function of monocytes and monocyte-derived macrophages in α1-antitrypsin deficiency.
Van't Wout EF; van Schadewijk A; Lomas DA; Stolk J; Marciniak SJ; Hiemstra PS
Eur Respir J; 2015 Feb; 45(2):365-76. PubMed ID: 25323228
[TBL] [Abstract][Full Text] [Related]
6. A C. elegans model of human α1-antitrypsin deficiency links components of the RNAi pathway to misfolded protein turnover.
Long OS; Benson JA; Kwak JH; Luke CJ; Gosai SJ; O'Reilly LP; Wang Y; Li J; Vetica AC; Miedel MT; Stolz DB; Watkins SC; Züchner S; Perlmutter DH; Silverman GA; Pak SC
Hum Mol Genet; 2014 Oct; 23(19):5109-22. PubMed ID: 24838286
[TBL] [Abstract][Full Text] [Related]
7. Selenoprotein S/SEPS1 modifies endoplasmic reticulum stress in Z variant alpha1-antitrypsin deficiency.
Kelly E; Greene CM; Carroll TP; McElvaney NG; O'Neill SJ
J Biol Chem; 2009 Jun; 284(25):16891-16897. PubMed ID: 19398551
[TBL] [Abstract][Full Text] [Related]
8. Protein Misfolding and Aggregation: The Relatedness between Parkinson's Disease and Hepatic Endoplasmic Reticulum Storage Disorders.
Padilla-Godínez FJ; Ramos-Acevedo R; Martínez-Becerril HA; Bernal-Conde LD; Garrido-Figueroa JF; Hiriart M; Hernández-López A; Argüero-Sánchez R; Callea F; Guerra-Crespo M
Int J Mol Sci; 2021 Nov; 22(22):. PubMed ID: 34830348
[TBL] [Abstract][Full Text] [Related]
9. Misfolded proteins bind and activate death receptor 5 to trigger apoptosis during unresolved endoplasmic reticulum stress.
Lam M; Marsters SA; Ashkenazi A; Walter P
Elife; 2020 Jan; 9():. PubMed ID: 31904339
[TBL] [Abstract][Full Text] [Related]
10. HRD1-mediated METTL14 degradation regulates m
Wei J; Harada BT; Lu D; Ma R; Gao B; Xu Y; Montauti E; Mani N; Chaudhuri SM; Gregory S; Weinberg SE; Zhang DD; Green R; He C; Fang D
Mol Cell; 2021 Dec; 81(24):5052-5065.e6. PubMed ID: 34847358
[TBL] [Abstract][Full Text] [Related]
11. Multiple Genes Core to ERAD, Macroautophagy and Lysosomal Degradation Pathways Participate in the Proteostasis Response in α1-Antitrypsin Deficiency.
Li J; Moretti F; Hidvegi T; Sviben S; Fitzpatrick JAJ; Sundaramoorthi H; Pak SC; Silverman GA; Knapp B; Filipuzzi I; Alford J; Reece-Hoyes J; Nigsch F; Murphy LO; Nyfeler B; Perlmutter DH
Cell Mol Gastroenterol Hepatol; 2024; 17(6):1007-1024. PubMed ID: 38336172
[TBL] [Abstract][Full Text] [Related]
12. Alpha1-antitrypsin deficiency: liver disease associated with retention of a mutant secretory glycoprotein in the endoplasmic reticulum.
Perlmutter DH
Methods Mol Biol; 2003; 232():39-56. PubMed ID: 12840538
[No Abstract] [Full Text] [Related]
13. The pathological Trento variant of alpha-1-antitrypsin (E75V) shows nonclassical behaviour during polymerization.
Miranda E; Ferrarotti I; Berardelli R; Laffranchi M; Cerea M; Gangemi F; Haq I; Ottaviani S; Lomas DA; Irving JA; Fra A
FEBS J; 2017 Jul; 284(13):2110-2126. PubMed ID: 28504839
[TBL] [Abstract][Full Text] [Related]
14. Hepatic and Extrahepatic Sources and Manifestations in Endoplasmic Reticulum Storage Diseases.
Callea F; Francalanci P; Giovannoni I
Int J Mol Sci; 2021 May; 22(11):. PubMed ID: 34071368
[TBL] [Abstract][Full Text] [Related]
15. Lifespan extension conferred by endoplasmic reticulum secretory pathway deficiency requires induction of the unfolded protein response.
Labunskyy VM; Gerashchenko MV; Delaney JR; Kaya A; Kennedy BK; Kaeberlein M; Gladyshev VN
PLoS Genet; 2014 Jan; 10(1):e1004019. PubMed ID: 24391512
[TBL] [Abstract][Full Text] [Related]
16. Aberrant disulphide bonding contributes to the ER retention of alpha1-antitrypsin deficiency variants.
Ronzoni R; Berardelli R; Medicina D; Sitia R; Gooptu B; Fra AM
Hum Mol Genet; 2016 Feb; 25(4):642-50. PubMed ID: 26647313
[TBL] [Abstract][Full Text] [Related]
17. The Mechanism of Mitochondrial Injury in Alpha-1 Antitrypsin Deficiency Mediated Liver Disease.
Khodayari N; Wang RL; Oshins R; Lu Y; Millett M; Aranyos AM; Mostofizadeh S; Scindia Y; Flagg TO; Brantly M
Int J Mol Sci; 2021 Dec; 22(24):. PubMed ID: 34948056
[TBL] [Abstract][Full Text] [Related]
18. When is the unfolded protein response not the unfolded protein response?
Howell SH
Plant Sci; 2017 Jul; 260():139-143. PubMed ID: 28554471
[TBL] [Abstract][Full Text] [Related]
19. Measuring the effects of α
Chambers JE; Dickens JA; Marciniak SJ
Biol Cell; 2018 Nov; 110(11):249-255. PubMed ID: 30129166
[TBL] [Abstract][Full Text] [Related]
20. Endoplasmic Reticulum Stress Response and Mutant Protein Degradation in CHO Cells Accumulating Antithrombin (C95R) in Russell Bodies.
Kimura K; Inoue K; Okubo J; Ueda Y; Kawaguchi K; Sakurai H; Wada I; Morita M; Imanaka T
Biol Pharm Bull; 2015; 38(12):1980-4. PubMed ID: 26447095
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
