These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.
2. Magnolol inhibits angiogenesis by regulating ROS-mediated apoptosis and the PI3K/AKT/mTOR signaling pathway in mES/EB-derived endothelial-like cells. Kim GD; Oh J; Park HJ; Bae K; Lee SK Int J Oncol; 2013 Aug; 43(2):600-10. PubMed ID: 23708970 [TBL] [Abstract][Full Text] [Related]
3. Involvement of PI3K-AKT-mTOR pathway in protein kinase CKII inhibition-mediated senescence in human colon cancer cells. Park JH; Kim JJ; Bae YS Biochem Biophys Res Commun; 2013 Apr; 433(4):420-5. PubMed ID: 23523798 [TBL] [Abstract][Full Text] [Related]
4. Plasma endothelial cells-derived extracellular vesicles promote wound healing in diabetes through YAP and the PI3K/Akt/mTOR pathway. Wei F; Wang A; Wang Q; Han W; Rong R; Wang L; Liu S; Zhang Y; Dong C; Li Y Aging (Albany NY); 2020 Jun; 12(12):12002-12018. PubMed ID: 32570219 [TBL] [Abstract][Full Text] [Related]
5. Pro-apoptotic and pro-autophagic effects of the Aurora kinase A inhibitor alisertib (MLN8237) on human osteosarcoma U-2 OS and MG-63 cells through the activation of mitochondria-mediated pathway and inhibition of p38 MAPK/PI3K/Akt/mTOR signaling pathway. Niu NK; Wang ZL; Pan ST; Ding HQ; Au GH; He ZX; Zhou ZW; Xiao G; Yang YX; Zhang X; Yang T; Chen XW; Qiu JX; Zhou SF Drug Des Devel Ther; 2015; 9():1555-84. PubMed ID: 25792811 [TBL] [Abstract][Full Text] [Related]
7. Emerging roles of the p38 MAPK and PI3K/AKT/mTOR pathways in oncogene-induced senescence. Xu Y; Li N; Xiang R; Sun P Trends Biochem Sci; 2014 Jun; 39(6):268-76. PubMed ID: 24818748 [TBL] [Abstract][Full Text] [Related]
8. AKT induces senescence in human cells via mTORC1 and p53 in the absence of DNA damage: implications for targeting mTOR during malignancy. Astle MV; Hannan KM; Ng PY; Lee RS; George AJ; Hsu AK; Haupt Y; Hannan RD; Pearson RB Oncogene; 2012 Apr; 31(15):1949-62. PubMed ID: 21909130 [TBL] [Abstract][Full Text] [Related]
9. 15(S)-HETE-induced angiogenesis in adipose tissue is mediated through activation of PI3K/Akt/mTOR signaling pathway. Soumya SJ; Binu S; Helen A; Reddanna P; Sudhakaran PR Biochem Cell Biol; 2013 Dec; 91(6):498-505. PubMed ID: 24219292 [TBL] [Abstract][Full Text] [Related]
10. The PI3K/Akt/mTOR pathway regulates the replicative senescence of human VSMCs. Tan P; Wang YJ; Li S; Wang Y; He JY; Chen YY; Deng HQ; Huang W; Zhan JK; Liu YS Mol Cell Biochem; 2016 Nov; 422(1-2):1-10. PubMed ID: 27619662 [TBL] [Abstract][Full Text] [Related]
11. Inhibition of the phosphatidylinositol 3-kinase/Akt/mammalian target of rapamycin pathway but not the MEK/ERK pathway attenuates laminin-mediated small cell lung cancer cellular survival and resistance to imatinib mesylate or chemotherapy. Tsurutani J; West KA; Sayyah J; Gills JJ; Dennis PA Cancer Res; 2005 Sep; 65(18):8423-32. PubMed ID: 16166321 [TBL] [Abstract][Full Text] [Related]
12. Myocyte enhancer factor 2A delays vascular endothelial cell senescence by activating the PI3K/p-Akt/SIRT1 pathway. Liu B; Wang L; Jiang W; Xiong Y; Pang L; Zhong Y; Zhang C; Ou W; Tian C; Chen X; Liu SM Aging (Albany NY); 2019 Jun; 11(11):3768-3784. PubMed ID: 31182679 [TBL] [Abstract][Full Text] [Related]
13. Inhibition of the PI3K-Akt and mTORC1 signaling pathways promotes the elongation of vascular endothelial cells. Tsuji-Tamura K; Ogawa M J Cell Sci; 2016 Mar; 129(6):1165-78. PubMed ID: 26826185 [TBL] [Abstract][Full Text] [Related]
14. Inhibitory effect of 14,15-EET on endothelial senescence through activation of mTOR complex 2/Akt signaling pathways. Yang C; Pan S; Yan S; Li Z; Yang J; Wang Y; Xiong Y Int J Biochem Cell Biol; 2014 May; 50():93-100. PubMed ID: 24607498 [TBL] [Abstract][Full Text] [Related]
15. Cooperative effects of Akt-1 and Raf-1 on the induction of cellular senescence in doxorubicin or tamoxifen treated breast cancer cells. Taylor JR; Lehmann BD; Chappell WH; Abrams SL; Steelman LS; McCubrey JA Oncotarget; 2011 Aug; 2(8):610-26. PubMed ID: 21881167 [TBL] [Abstract][Full Text] [Related]
16. Plumbagin induces G2/M arrest, apoptosis, and autophagy via p38 MAPK- and PI3K/Akt/mTOR-mediated pathways in human tongue squamous cell carcinoma cells. Pan ST; Qin Y; Zhou ZW; He ZX; Zhang X; Yang T; Yang YX; Wang D; Qiu JX; Zhou SF Drug Des Devel Ther; 2015; 9():1601-26. PubMed ID: 25834400 [TBL] [Abstract][Full Text] [Related]
17. Vascular endothelial cells senescence is associated with NOD-like receptor family pyrin domain-containing 3 (NLRP3) inflammasome activation via reactive oxygen species (ROS)/thioredoxin-interacting protein (TXNIP) pathway. Yin Y; Zhou Z; Liu W; Chang Q; Sun G; Dai Y Int J Biochem Cell Biol; 2017 Mar; 84():22-34. PubMed ID: 28064010 [TBL] [Abstract][Full Text] [Related]
18. Bradykinin protects cardiac c-kit positive cells from high-glucose-induced senescence through B2 receptor signaling pathway. Fu C; Cao Y; Li B; Xu R; Sun Y; Yao Y J Cell Biochem; 2019 Oct; 120(10):17731-17743. PubMed ID: 31119778 [TBL] [Abstract][Full Text] [Related]
19. Inhibition of mTOR activity restores tamoxifen response in breast cancer cells with aberrant Akt Activity. deGraffenried LA; Friedrichs WE; Russell DH; Donzis EJ; Middleton AK; Silva JM; Roth RA; Hidalgo M Clin Cancer Res; 2004 Dec; 10(23):8059-67. PubMed ID: 15585641 [TBL] [Abstract][Full Text] [Related]