These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

159 related articles for article (PubMed ID: 27568562)

  • 1. Mdm2 Phosphorylation Regulates Its Stability and Has Contrasting Effects on Oncogene and Radiation-Induced Tumorigenesis.
    Carr MI; Roderick JE; Gannon HS; Kelliher MA; Jones SN
    Cell Rep; 2016 Sep; 16(10):2618-2629. PubMed ID: 27568562
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Phosphorylation of the Mdm2 oncoprotein by the c-Abl tyrosine kinase regulates p53 tumor suppression and the radiosensitivity of mice.
    Carr MI; Roderick JE; Zhang H; Woda BA; Kelliher MA; Jones SN
    Proc Natl Acad Sci U S A; 2016 Dec; 113(52):15024-15029. PubMed ID: 27956626
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Oncogenic c-Myc-induced lymphomagenesis is inhibited non-redundantly by the p19Arf-Mdm2-p53 and RP-Mdm2-p53 pathways.
    Meng X; Carlson NR; Dong J; Zhang Y
    Oncogene; 2015 Nov; 34(46):5709-17. PubMed ID: 25823025
    [TBL] [Abstract][Full Text] [Related]  

  • 4. ATM phosphorylation of Mdm2 Ser394 regulates the amplitude and duration of the DNA damage response in mice.
    Gannon HS; Woda BA; Jones SN
    Cancer Cell; 2012 May; 21(5):668-679. PubMed ID: 22624716
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Mdm2 phosphorylation by Akt regulates the p53 response to oxidative stress to promote cell proliferation and tumorigenesis.
    Chibaya L; Karim B; Zhang H; Jones SN
    Proc Natl Acad Sci U S A; 2021 Jan; 118(4):. PubMed ID: 33468664
    [TBL] [Abstract][Full Text] [Related]  

  • 6. The p53-Mdm2 feedback loop protects against DNA damage by inhibiting p53 activity but is dispensable for p53 stability, development, and longevity.
    Pant V; Xiong S; Jackson JG; Post SM; Abbas HA; Quintás-Cardama A; Hamir AN; Lozano G
    Genes Dev; 2013 Sep; 27(17):1857-67. PubMed ID: 23973961
    [TBL] [Abstract][Full Text] [Related]  

  • 7. ATM-dependent phosphorylation of Mdm2 on serine 395: role in p53 activation by DNA damage.
    Maya R; Balass M; Kim ST; Shkedy D; Leal JF; Shifman O; Moas M; Buschmann T; Ronai Z; Shiloh Y; Kastan MB; Katzir E; Oren M
    Genes Dev; 2001 May; 15(9):1067-77. PubMed ID: 11331603
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Inactivation of ribosomal protein S27-like confers radiosensitivity via the Mdm2-p53 and Mdm2-MRN-ATM axes.
    Zhao Y; Tan M; Liu X; Xiong X; Sun Y
    Cell Death Dis; 2018 Feb; 9(2):145. PubMed ID: 29396424
    [TBL] [Abstract][Full Text] [Related]  

  • 9. ATM and Chk2-dependent phosphorylation of MDMX contribute to p53 activation after DNA damage.
    Chen L; Gilkes DM; Pan Y; Lane WS; Chen J
    EMBO J; 2005 Oct; 24(19):3411-22. PubMed ID: 16163388
    [TBL] [Abstract][Full Text] [Related]  

  • 10. LRRK2 interacts with ATM and regulates Mdm2-p53 cell proliferation axis in response to genotoxic stress.
    Chen Z; Cao Z; Zhang W; Gu M; Zhou ZD; Li B; Li J; Tan EK; Zeng L
    Hum Mol Genet; 2017 Nov; 26(22):4494-4505. PubMed ID: 28973420
    [TBL] [Abstract][Full Text] [Related]  

  • 11. p53 dynamics in response to DNA damage vary across cell lines and are shaped by efficiency of DNA repair and activity of the kinase ATM.
    Stewart-Ornstein J; Lahav G
    Sci Signal; 2017 Apr; 10(476):. PubMed ID: 28442631
    [TBL] [Abstract][Full Text] [Related]  

  • 12. A single synonymous mutation determines the phosphorylation and stability of the nascent protein.
    Karakostis K; Vadivel Gnanasundram S; López I; Thermou A; Wang L; Nylander K; Olivares-Illana V; Fåhraeus R
    J Mol Cell Biol; 2019 Mar; 11(3):187-199. PubMed ID: 30252118
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Loss of the ARF tumor suppressor reverses premature replicative arrest but not radiation hypersensitivity arising from disabled atm function.
    Kamijo T; van de Kamp E; Chong MJ; Zindy F; Diehl JA; Sherr CJ; McKinnon PJ
    Cancer Res; 1999 May; 59(10):2464-9. PubMed ID: 10344759
    [TBL] [Abstract][Full Text] [Related]  

  • 14. The Wip1 Phosphatase acts as a gatekeeper in the p53-Mdm2 autoregulatory loop.
    Lu X; Ma O; Nguyen TA; Jones SN; Oren M; Donehower LA
    Cancer Cell; 2007 Oct; 12(4):342-54. PubMed ID: 17936559
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Bax loss impairs Myc-induced apoptosis and circumvents the selection of p53 mutations during Myc-mediated lymphomagenesis.
    Eischen CM; Roussel MF; Korsmeyer SJ; Cleveland JL
    Mol Cell Biol; 2001 Nov; 21(22):7653-62. PubMed ID: 11604501
    [TBL] [Abstract][Full Text] [Related]  

  • 16. An ARF-independent c-MYC-activated tumor suppression pathway mediated by ribosomal protein-Mdm2 Interaction.
    Macias E; Jin A; Deisenroth C; Bhat K; Mao H; Lindström MS; Zhang Y
    Cancer Cell; 2010 Sep; 18(3):231-43. PubMed ID: 20832751
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Haploinsufficiency of Mdm2 and Mdm4 in tumorigenesis and development.
    Terzian T; Wang Y; Van Pelt CS; Box NF; Travis EL; Lozano G
    Mol Cell Biol; 2007 Aug; 27(15):5479-85. PubMed ID: 17526734
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Atm deficiency affects both apoptosis and proliferation to augment Myc-induced lymphomagenesis.
    Maclean KH; Kastan MB; Cleveland JL
    Mol Cancer Res; 2007 Jul; 5(7):705-11. PubMed ID: 17634425
    [TBL] [Abstract][Full Text] [Related]  

  • 19. [Expression and clinical significance of P53 pathway-associated proteins in pancreatic carcinoma].
    Yu GZ; Zhu MH; Chen Y; Ni CR; Li FM
    Ai Zheng; 2005 Nov; 24(11):1398-403. PubMed ID: 16552971
    [TBL] [Abstract][Full Text] [Related]  

  • 20. SIRT7-dependent deacetylation of NPM promotes p53 stabilization following UV-induced genotoxic stress.
    Ianni A; Kumari P; Tarighi S; Simonet NG; Popescu D; Guenther S; Hölper S; Schmidt A; Smolka C; Yue S; Krüger M; Fiorillo C; Vaquero A; Bober E; Braun T
    Proc Natl Acad Sci U S A; 2021 Feb; 118(5):. PubMed ID: 33495326
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.