These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.
173 related articles for article (PubMed ID: 27569291)
1. Involvement of organic cation transporter 3 (Oct3/Slc22a3) in the bioavailability and pharmacokinetics of antidiabetic metformin in mice. Shirasaka Y; Lee N; Zha W; Wagner D; Wang J Drug Metab Pharmacokinet; 2016 Oct; 31(5):385-388. PubMed ID: 27569291 [TBL] [Abstract][Full Text] [Related]
2. Targeted disruption of organic cation transporter 3 attenuates the pharmacologic response to metformin. Chen EC; Liang X; Yee SW; Geier EG; Stocker SL; Chen L; Giacomini KM Mol Pharmacol; 2015 Jul; 88(1):75-83. PubMed ID: 25920679 [TBL] [Abstract][Full Text] [Related]
3. Clinical pharmacokinetics of metformin. Graham GG; Punt J; Arora M; Day RO; Doogue MP; Duong JK; Furlong TJ; Greenfield JR; Greenup LC; Kirkpatrick CM; Ray JE; Timmins P; Williams KM Clin Pharmacokinet; 2011 Feb; 50(2):81-98. PubMed ID: 21241070 [TBL] [Abstract][Full Text] [Related]
4. Disposition of metformin: variability due to polymorphisms of organic cation transporters. Zolk O Ann Med; 2012 Mar; 44(2):119-29. PubMed ID: 21366511 [TBL] [Abstract][Full Text] [Related]
5. Taste of a pill: organic cation transporter-3 (OCT3) mediates metformin accumulation and secretion in salivary glands. Lee N; Duan H; Hebert MF; Liang CJ; Rice KM; Wang J J Biol Chem; 2014 Sep; 289(39):27055-27064. PubMed ID: 25107910 [TBL] [Abstract][Full Text] [Related]
6. Involvement of carnitine/organic cation transporter OCTN1/SLC22A4 in gastrointestinal absorption of metformin. Nakamichi N; Shima H; Asano S; Ishimoto T; Sugiura T; Matsubara K; Kusuhara H; Sugiyama Y; Sai Y; Miyamoto K; Tsuji A; Kato Y J Pharm Sci; 2013 Sep; 102(9):3407-17. PubMed ID: 23666872 [TBL] [Abstract][Full Text] [Related]
7. Organic Cation Transporter 3 Facilitates Fetal Exposure to Metformin during Pregnancy. Lee N; Hebert MF; Wagner DJ; Easterling TR; Liang CJ; Rice K; Wang J Mol Pharmacol; 2018 Oct; 94(4):1125-1131. PubMed ID: 30012584 [TBL] [Abstract][Full Text] [Related]
8. Organic cation transporter 3: expression in failing and nonfailing human heart and functional characterization. Solbach TF; Grube M; Fromm MF; Zolk O J Cardiovasc Pharmacol; 2011 Oct; 58(4):409-17. PubMed ID: 21697722 [TBL] [Abstract][Full Text] [Related]
9. Polymorphism of organic cation transporter 2 improves glucose-lowering effect of metformin via influencing its pharmacokinetics in Chinese type 2 diabetic patients. Hou W; Zhang D; Lu W; Zheng T; Wan L; Li Q; Bao Y; Liu F; Jia W Mol Diagn Ther; 2015 Feb; 19(1):25-33. PubMed ID: 25573751 [TBL] [Abstract][Full Text] [Related]
10. Effect of Pharmaceutical Excipients on Intestinal Absorption of Metformin via Organic Cation-Selective Transporters. Ruan Y; Li X; You L; Chen J; Shen Y; Zhang J; Yuan Y; Kang L; Qin C; Wu C Mol Pharm; 2021 Jun; 18(6):2198-2207. PubMed ID: 33956455 [TBL] [Abstract][Full Text] [Related]
11. Pharmacogenetic variation and metformin response. Chen S; Zhou J; Xi M; Jia Y; Wong Y; Zhao J; Ding L; Zhang J; Wen A Curr Drug Metab; 2013 Dec; 14(10):1070-82. PubMed ID: 24329113 [TBL] [Abstract][Full Text] [Related]
12. Effects of the genetic variants of organic cation transporters 1 and 3 on the pharmacokinetics of metformin in Jordanians. Hakooz N; Jarrar YB; Zihlif M; Imraish A; Hamed S; Arafat T Drug Metab Pers Ther; 2017 Sep; 32(3):157-162. PubMed ID: 28862982 [TBL] [Abstract][Full Text] [Related]
13. Expression of organic cation transporters OCT1 (SLC22A1) and OCT3 (SLC22A3) is affected by genetic factors and cholestasis in human liver. Nies AT; Koepsell H; Winter S; Burk O; Klein K; Kerb R; Zanger UM; Keppler D; Schwab M; Schaeffeler E Hepatology; 2009 Oct; 50(4):1227-40. PubMed ID: 19591196 [TBL] [Abstract][Full Text] [Related]
14. Mechanisms for membrane transport of metformin in human intestinal epithelial Caco-2 cells. Horie A; Sakata J; Nishimura M; Ishida K; Taguchi M; Hashimoto Y Biopharm Drug Dispos; 2011 Jul; 32(5):253-60. PubMed ID: 21567399 [TBL] [Abstract][Full Text] [Related]
15. OCT3 promoter haplotype is associated with metformin pharmacokinetics in Koreans. Kwon EY; Chung JY; Park HJ; Kim BM; Kim M; Choi JH Sci Rep; 2018 Nov; 8(1):16965. PubMed ID: 30446679 [TBL] [Abstract][Full Text] [Related]
16. Transfer of metformin across the rat placenta is mediated by organic cation transporter 3 (OCT3/SLC22A3) and multidrug and toxin extrusion 1 (MATE1/SLC47A1) protein. Ahmadimoghaddam D; Staud F Reprod Toxicol; 2013 Aug; 39():17-22. PubMed ID: 23562376 [TBL] [Abstract][Full Text] [Related]
17. Role of organic cation transporter 3 (SLC22A3) and its missense variants in the pharmacologic action of metformin. Chen L; Pawlikowski B; Schlessinger A; More SS; Stryke D; Johns SJ; Portman MA; Chen E; Ferrin TE; Sali A; Giacomini KM Pharmacogenet Genomics; 2010 Nov; 20(11):687-99. PubMed ID: 20859243 [TBL] [Abstract][Full Text] [Related]
18. Goldenseal-Mediated Inhibition of Intestinal Uptake Transporters Decreases Metformin Systemic Exposure in Mice. Oyanna VO; Garcia-Torres KY; Bechtold BJ; Lynch KD; Call MR; Horváth M; Manwill PK; Graf TN; Cech NB; Oberlies NH; Paine MF; Clarke JD Drug Metab Dispos; 2023 Nov; 51(11):1483-1489. PubMed ID: 37562957 [TBL] [Abstract][Full Text] [Related]
19. Ablation of both organic cation transporter (OCT)1 and OCT2 alters metformin pharmacokinetics but has no effect on tissue drug exposure and pharmacodynamics. Higgins JW; Bedwell DW; Zamek-Gliszczynski MJ Drug Metab Dispos; 2012 Jun; 40(6):1170-7. PubMed ID: 22407892 [TBL] [Abstract][Full Text] [Related]
20. Role of organic cation transporters in drug-drug interaction. Koepsell H Expert Opin Drug Metab Toxicol; 2015; 11(10):1619-33. PubMed ID: 26206523 [TBL] [Abstract][Full Text] [Related] [Next] [New Search]