These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

286 related articles for article (PubMed ID: 27570076)

  • 21. DNAJB6 is a peptide-binding chaperone which can suppress amyloid fibrillation of polyglutamine peptides at substoichiometric molar ratios.
    Månsson C; Kakkar V; Monsellier E; Sourigues Y; Härmark J; Kampinga HH; Melki R; Emanuelsson C
    Cell Stress Chaperones; 2014 Mar; 19(2):227-39. PubMed ID: 23904097
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Measurement of Chaperone-Mediated Effects on Polyglutamine Protein Aggregation by the Filter Trap Assay.
    van Waarde-Verhagen MAWH; Kampinga HH
    Methods Mol Biol; 2018; 1709():59-74. PubMed ID: 29177651
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Compartment-Dependent Degradation of Mutant Huntingtin Accounts for Its Preferential Accumulation in Neuronal Processes.
    Zhao T; Hong Y; Li S; Li XJ
    J Neurosci; 2016 Aug; 36(32):8317-28. PubMed ID: 27511006
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Formation and toxicity of soluble polyglutamine oligomers in living cells.
    Lajoie P; Snapp EL
    PLoS One; 2010 Dec; 5(12):e15245. PubMed ID: 21209946
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Antisense downregulation of mutant huntingtin in a cell model.
    Hasholt L; Abell K; Nørremølle A; Nellemann C; Fenger K; Sørensen SA
    J Gene Med; 2003 Jun; 5(6):528-38. PubMed ID: 12797118
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Suppression of polyglutamine-induced toxicity in cell and animal models of Huntington's disease by ubiquilin.
    Wang H; Lim PJ; Yin C; Rieckher M; Vogel BE; Monteiro MJ
    Hum Mol Genet; 2006 Mar; 15(6):1025-41. PubMed ID: 16461334
    [TBL] [Abstract][Full Text] [Related]  

  • 27. Huntingtin Polyglutamine-Dependent Protein Aggregation in Reconstituted Cells.
    Machida K; Kanzawa K; Shigeta T; Yamamoto Y; Tsumoto K; Imataka H
    ACS Synth Biol; 2018 Feb; 7(2):377-383. PubMed ID: 29232946
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Formation of toxic oligomers of polyQ-expanded Huntingtin by prion-mediated cross-seeding.
    Gropp MHM; Klaips CL; Hartl FU
    Mol Cell; 2022 Nov; 82(22):4290-4306.e11. PubMed ID: 36272412
    [TBL] [Abstract][Full Text] [Related]  

  • 29. The dynamics of early-state transcriptional changes and aggregate formation in a Huntington's disease cell model.
    van Hagen M; Piebes DGE; de Leeuw WC; Vuist IM; van Roon-Mom WMC; Moerland PD; Verschure PJ
    BMC Genomics; 2017 May; 18(1):373. PubMed ID: 28499347
    [TBL] [Abstract][Full Text] [Related]  

  • 30. Oxidative stress promotes mutant huntingtin aggregation and mutant huntingtin-dependent cell death by mimicking proteasomal malfunction.
    Goswami A; Dikshit P; Mishra A; Mulherkar S; Nukina N; Jana NR
    Biochem Biophys Res Commun; 2006 Mar; 342(1):184-90. PubMed ID: 16472774
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Aggregate formation inhibits proteasomal degradation of polyglutamine proteins.
    Verhoef LG; Lindsten K; Masucci MG; Dantuma NP
    Hum Mol Genet; 2002 Oct; 11(22):2689-700. PubMed ID: 12374759
    [TBL] [Abstract][Full Text] [Related]  

  • 32. [Protein-Protein Interactions of Huntingtin in the Hippocampus].
    Proskura AL; Vechkapova SO; Zapara TA; Ratushniak AS
    Mol Biol (Mosk); 2017; 51(4):734-742. PubMed ID: 28900094
    [TBL] [Abstract][Full Text] [Related]  

  • 33. PolyQ-expanded huntingtin and ataxin-3 sequester ubiquitin adaptors hHR23B and UBQLN2 into aggregates via conjugated ubiquitin.
    Yang H; Yue HW; He WT; Hong JY; Jiang LL; Hu HY
    FASEB J; 2018 Jun; 32(6):2923-2933. PubMed ID: 29401586
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Anti-PolyQ Antibodies Recognize a Short PolyQ Stretch in Both Normal and Mutant Huntingtin Exon 1.
    Owens GE; New DM; West AP; Bjorkman PJ
    J Mol Biol; 2015 Jul; 427(15):2507-2519. PubMed ID: 26047735
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Identification of anti-prion compounds as efficient inhibitors of polyglutamine protein aggregation in a zebrafish model.
    Schiffer NW; Broadley SA; Hirschberger T; Tavan P; Kretzschmar HA; Giese A; Haass C; Hartl FU; Schmid B
    J Biol Chem; 2007 Mar; 282(12):9195-203. PubMed ID: 17170113
    [TBL] [Abstract][Full Text] [Related]  

  • 36. Small molecule inducers of heat-shock response reduce polyQ-mediated huntingtin aggregation. A possible therapeutic strategy.
    Herbst M; Wanker EE
    Neurodegener Dis; 2007; 4(2-3):254-60. PubMed ID: 17596719
    [TBL] [Abstract][Full Text] [Related]  

  • 37. Differential roles for DNAJ isoforms in HTT-polyQ and FUS aggregation modulation revealed by chaperone screens.
    Rozales K; Younis A; Saida N; Meller A; Goldman H; Kellerman L; Heinrich R; Berlin S; Shalgi R
    Nat Commun; 2022 Jan; 13(1):516. PubMed ID: 35082301
    [TBL] [Abstract][Full Text] [Related]  

  • 38. Discovery of Arginine Ethyl Ester as Polyglutamine Aggregation Inhibitor: Conformational Transitioning of Huntingtin N-Terminus Augments Aggregation Suppression.
    Singh V; Patel KA; Sharma RK; Patil PR; Joshi AS; Parihar R; Athilingam T; Sinha N; Ganesh S; Sinha P; Roy I; Thakur AK
    ACS Chem Neurosci; 2019 Sep; 10(9):3969-3985. PubMed ID: 31460743
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Proteostasis of Huntingtin in Health and Disease.
    Koyuncu S; Fatima A; Gutierrez-Garcia R; Vilchez D
    Int J Mol Sci; 2017 Jul; 18(7):. PubMed ID: 28753941
    [TBL] [Abstract][Full Text] [Related]  

  • 40. Role of the ribosomal quality control machinery in nucleocytoplasmic translocation of polyQ-expanded huntingtin exon-1.
    Zheng J; Yang J; Choe YJ; Hao X; Cao X; Zhao Q; Zhang Y; Franssens V; Hartl FU; Nyström T; Winderickx J; Liu B
    Biochem Biophys Res Commun; 2017 Nov; 493(1):708-717. PubMed ID: 28864412
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 15.