BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

269 related articles for article (PubMed ID: 27572106)

  • 1. Aldehyde dehydrogenase 1a3 defines a subset of failing pancreatic β cells in diabetic mice.
    Kim-Muller JY; Fan J; Kim YJ; Lee SA; Ishida E; Blaner WS; Accili D
    Nat Commun; 2016 Aug; 7():12631. PubMed ID: 27572106
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Enhancing Acsl4 in absence of mTORC2/Rictor drove β-cell dedifferentiation via inhibiting FoxO1 and promoting ROS production.
    Cui C; Li T; Xie Y; Yang J; Fu C; Qiu Y; Shen L; Ni Q; Wang Q; Nie A; Ning G; Wang W; Gu Y
    Biochim Biophys Acta Mol Basis Dis; 2021 Dec; 1867(12):166261. PubMed ID: 34455055
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Evidence of β-Cell Dedifferentiation in Human Type 2 Diabetes.
    Cinti F; Bouchi R; Kim-Muller JY; Ohmura Y; Sandoval PR; Masini M; Marselli L; Suleiman M; Ratner LE; Marchetti P; Accili D
    J Clin Endocrinol Metab; 2016 Mar; 101(3):1044-54. PubMed ID: 26713822
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Pancreatic β cell dedifferentiation as a mechanism of diabetic β cell failure.
    Talchai C; Xuan S; Lin HV; Sussel L; Accili D
    Cell; 2012 Sep; 150(6):1223-34. PubMed ID: 22980982
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Incomplete Re-Expression of Neuroendocrine Progenitor/Stem Cell Markers is a Key Feature of β-Cell Dedifferentiation.
    Neelankal John A; Morahan G; Jiang FX
    J Neuroendocrinol; 2017 Jan; 29(1):. PubMed ID: 27891681
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Cyb5r3 links FoxO1-dependent mitochondrial dysfunction with β-cell failure.
    Fan J; Du W; Kim-Muller JY; Son J; Kuo T; Larrea D; Garcia C; Kitamoto T; Kraakman MJ; Owusu-Ansah E; Cirulli V; Accili D
    Mol Metab; 2020 Apr; 34():97-111. PubMed ID: 32180563
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Activation of ACE2/angiotensin (1-7) attenuates pancreatic β cell dedifferentiation in a high-fat-diet mouse model.
    Xuan X; Gao F; Ma X; Huang C; Wang Y; Deng H; Wang S; Li W; Yuan L
    Metabolism; 2018 Apr; 81():83-96. PubMed ID: 29225087
    [TBL] [Abstract][Full Text] [Related]  

  • 8. FoxO1 Deacetylation Decreases Fatty Acid Oxidation in β-Cells and Sustains Insulin Secretion in Diabetes.
    Kim-Muller JY; Kim YJ; Fan J; Zhao S; Banks AS; Prentki M; Accili D
    J Biol Chem; 2016 May; 291(19):10162-72. PubMed ID: 26984405
    [TBL] [Abstract][Full Text] [Related]  

  • 9. FoxO1 as a double-edged sword in the pancreas: analysis of pancreas- and β-cell-specific FoxO1 knockout mice.
    Kobayashi M; Kikuchi O; Sasaki T; Kim HJ; Yokota-Hashimoto H; Lee YS; Amano K; Kitazumi T; Susanti VY; Kitamura YI; Kitamura T
    Am J Physiol Endocrinol Metab; 2012 Mar; 302(5):E603-13. PubMed ID: 22215655
    [TBL] [Abstract][Full Text] [Related]  

  • 10. β-cell dedifferentiation in diabetes is important, but what is it?
    Weir GC; Aguayo-Mazzucato C; Bonner-Weir S
    Islets; 2013; 5(5):233-7. PubMed ID: 24356710
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Increased expression of the glucose-responsive gene, RCAN1, causes hypoinsulinemia, β-cell dysfunction, and diabetes.
    Peiris H; Raghupathi R; Jessup CF; Zanin MP; Mohanasundaram D; Mackenzie KD; Chataway T; Clarke JN; Brealey J; Coates PT; Pritchard MA; Keating DJ
    Endocrinology; 2012 Nov; 153(11):5212-21. PubMed ID: 23011918
    [TBL] [Abstract][Full Text] [Related]  

  • 12. microRNA-483 Protects Pancreatic β-Cells by Targeting ALDH1A3.
    Wang Z; Mohan R; Chen X; Matson K; Waugh J; Mao Y; Zhang S; Li W; Tang X; Satin LS; Tang X
    Endocrinology; 2021 May; 162(5):. PubMed ID: 33564883
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Nε-(carboxymethyl) lysine-induced mitochondrial fission and mitophagy cause decreased insulin secretion from β-cells.
    Lo MC; Chen MH; Lee WS; Lu CI; Chang CR; Kao SH; Lee HM
    Am J Physiol Endocrinol Metab; 2015 Nov; 309(10):E829-39. PubMed ID: 26394662
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Mitochondrial regulation of β-cell function: maintaining the momentum for insulin release.
    Kaufman BA; Li C; Soleimanpour SA
    Mol Aspects Med; 2015 Apr; 42():91-104. PubMed ID: 25659350
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Androgen receptor-deficient islet β-cells exhibit alteration in genetic markers of insulin secretion and inflammation. A transcriptome analysis in the male mouse.
    Xu W; Niu T; Xu B; Navarro G; Schipma MJ; Mauvais-Jarvis F
    J Diabetes Complications; 2017 May; 31(5):787-795. PubMed ID: 28343791
    [TBL] [Abstract][Full Text] [Related]  

  • 16. When β-cells fail: lessons from dedifferentiation.
    Accili D; Talchai SC; Kim-Muller JY; Cinti F; Ishida E; Ordelheide AM; Kuo T; Fan J; Son J
    Diabetes Obes Metab; 2016 Sep; 18 Suppl 1(Suppl 1):117-22. PubMed ID: 27615140
    [TBL] [Abstract][Full Text] [Related]  

  • 17. YY1 deficiency in β-cells leads to mitochondrial dysfunction and diabetes in mice.
    Song D; Yang Q; Jiang X; Shan A; Nan J; Lei Y; Ji H; Di W; Yang T; Wang T; Wang W; Ning G; Cao Y
    Metabolism; 2020 Nov; 112():154353. PubMed ID: 32916152
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Abnormal mitochondrial function impairs calcium influx in diabetic mouse pancreatic beta cells.
    Li F; Porterfield DM; Zheng XY; Wang WJ; Xu Y; Zhang ZM
    Chin Med J (Engl); 2012 Feb; 125(3):502-10. PubMed ID: 22490411
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Mechanisms of β-cell dedifferentiation in diabetes: recent findings and future research directions.
    Bensellam M; Jonas JC; Laybutt DR
    J Endocrinol; 2018 Feb; 236(2):R109-R143. PubMed ID: 29203573
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Paraneoplastic β Cell Dedifferentiation in Nondiabetic Patients with Pancreatic Cancer.
    Wang Y; Ni Q; Sun J; Xu M; Xie J; Zhang J; Fang Y; Ning G; Wang Q
    J Clin Endocrinol Metab; 2020 Apr; 105(4):. PubMed ID: 31781763
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 14.