BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

362 related articles for article (PubMed ID: 27573877)

  • 1. Novel roles of amyloid-beta precursor protein metabolites in fragile X syndrome and autism.
    Westmark CJ; Sokol DK; Maloney B; Lahiri DK
    Mol Psychiatry; 2016 Oct; 21(10):1333-41. PubMed ID: 27573877
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Finding novel distinctions between the sAPPα-mediated anabolic biochemical pathways in Autism Spectrum Disorder and Fragile X Syndrome plasma and brain tissue.
    Ray B; Sokol DK; Maloney B; Lahiri DK
    Sci Rep; 2016 May; 6():26052. PubMed ID: 27212113
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Autism, Alzheimer disease, and fragile X: APP, FMRP, and mGluR5 are molecular links.
    Sokol DK; Maloney B; Long JM; Ray B; Lahiri DK
    Neurology; 2011 Apr; 76(15):1344-52. PubMed ID: 21482951
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Reversal of fragile X phenotypes by manipulation of AβPP/Aβ levels in Fmr1KO mice.
    Westmark CJ; Westmark PR; O'Riordan KJ; Ray BC; Hervey CM; Salamat MS; Abozeid SH; Stein KM; Stodola LA; Tranfaglia M; Burger C; Berry-Kravis EM; Malter JS
    PLoS One; 2011; 6(10):e26549. PubMed ID: 22046307
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Peripheral Amyloid Precursor Protein Derivative Expression in Fragile X Syndrome.
    McLane RD; Schmitt LM; Pedapati EV; Shaffer RC; Dominick KC; Horn PS; Gross C; Erickson CA
    Front Integr Neurosci; 2019; 13():49. PubMed ID: 31551722
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Serum matrix metalloproteinase-9 (MMP9) and amyloid-beta protein precursor (APP) as potential biomarkers in children with Fragile-X syndrome: A cross sectional study.
    Bekheet MHY; Mansour LA; Elkaffas RH; Kamel MA; Elmonem MA
    Clin Biochem; 2023 Nov; 121-122():110659. PubMed ID: 37797798
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Alzheimer's disease.
    De-Paula VJ; Radanovic M; Diniz BS; Forlenza OV
    Subcell Biochem; 2012; 65():329-52. PubMed ID: 23225010
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Impact of acamprosate on plasma amyloid-β precursor protein in youth: a pilot analysis in fragile X syndrome-associated and idiopathic autism spectrum disorder suggests a pharmacodynamic protein marker.
    Erickson CA; Ray B; Maloney B; Wink LK; Bowers K; Schaefer TL; McDougle CJ; Sokol DK; Lahiri DK
    J Psychiatr Res; 2014 Dec; 59():220-8. PubMed ID: 25300441
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Zinc and Copper Differentially Modulate Amyloid Precursor Protein Processing by γ-Secretase and Amyloid-β Peptide Production.
    Gerber H; Wu F; Dimitrov M; Garcia Osuna GM; Fraering PC
    J Biol Chem; 2017 Mar; 292(9):3751-3767. PubMed ID: 28096459
    [TBL] [Abstract][Full Text] [Related]  

  • 10. The roles of amyloid precursor protein (APP) in neurogenesis: Implications to pathogenesis and therapy of Alzheimer disease.
    Zhou ZD; Chan CH; Ma QH; Xu XH; Xiao ZC; Tan EK
    Cell Adh Migr; 2011; 5(4):280-92. PubMed ID: 21785276
    [TBL] [Abstract][Full Text] [Related]  

  • 11. CNS amyloid-β, soluble APP-α and -β kinetics during BACE inhibition.
    Dobrowolska JA; Michener MS; Wu G; Patterson BW; Chott R; Ovod V; Pyatkivskyy Y; Wildsmith KR; Kasten T; Mathers P; Dancho M; Lennox C; Smith BE; Gilberto D; McLoughlin D; Holder DJ; Stamford AW; Yarasheski KE; Kennedy ME; Savage MJ; Bateman RJ
    J Neurosci; 2014 Jun; 34(24):8336-46. PubMed ID: 24920637
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Age-Dependent Dysregulation of APP in Neuronal and Skin Cells from Fragile X Individuals.
    Cencelli G; Pacini L; De Luca A; Messia I; Gentile A; Kang Y; Nobile V; Tabolacci E; Jin P; Farace MG; Bagni C
    Cells; 2023 Feb; 12(5):. PubMed ID: 36899894
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Amyloid precursor protein glycosylation is altered in the brain of patients with Alzheimer's disease.
    Boix CP; Lopez-Font I; Cuchillo-Ibañez I; Sáez-Valero J
    Alzheimers Res Ther; 2020 Aug; 12(1):96. PubMed ID: 32787955
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Dysregulated ADAM10-Mediated Processing of APP during a Critical Time Window Leads to Synaptic Deficits in Fragile X Syndrome.
    Pasciuto E; Ahmed T; Wahle T; Gardoni F; D'Andrea L; Pacini L; Jacquemont S; Tassone F; Balschun D; Dotti CG; Callaerts-Vegh Z; D'Hooge R; Müller UC; Di Luca M; De Strooper B; Bagni C
    Neuron; 2015 Jul; 87(2):382-98. PubMed ID: 26182420
    [TBL] [Abstract][Full Text] [Related]  

  • 15. What's hAPPening at synapses? The role of amyloid β-protein precursor and β-amyloid in neurological disorders.
    Westmark CJ
    Mol Psychiatry; 2013 Apr; 18(4):425-34. PubMed ID: 22925831
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Increased secreted amyloid precursor protein-α (sAPPα) in severe autism: proposal of a specific, anabolic pathway and putative biomarker.
    Ray B; Long JM; Sokol DK; Lahiri DK
    PLoS One; 2011; 6(6):e20405. PubMed ID: 21731612
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Alternative Selection of β-Site APP-Cleaving Enzyme 1 (BACE1) Cleavage Sites in Amyloid β-Protein Precursor (APP) Harboring Protective and Pathogenic Mutations within the Aβ Sequence.
    Kimura A; Hata S; Suzuki T
    J Biol Chem; 2016 Nov; 291(46):24041-24053. PubMed ID: 27687728
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Differential effects of familial Alzheimer's disease-causing mutations on amyloid precursor protein (APP) trafficking, proteolytic conversion, and synaptogenic activity.
    Schilling S; Pradhan A; Heesch A; Helbig A; Blennow K; Koch C; Bertgen L; Koo EH; Brinkmalm G; Zetterberg H; Kins S; Eggert S
    Acta Neuropathol Commun; 2023 Jun; 11(1):87. PubMed ID: 37259128
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Decrease in brain soluble amyloid precursor protein β (sAPPβ) in Alzheimer's disease cortex.
    Wu G; Sankaranarayanan S; Hsieh SH; Simon AJ; Savage MJ
    J Neurosci Res; 2011 Jun; 89(6):822-32. PubMed ID: 21433051
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Cryptotanshinone, a compound from Salvia miltiorrhiza modulates amyloid precursor protein metabolism and attenuates beta-amyloid deposition through upregulating alpha-secretase in vivo and in vitro.
    Mei Z; Zhang F; Tao L; Zheng W; Cao Y; Wang Z; Tang S; Le K; Chen S; Pi R; Liu P
    Neurosci Lett; 2009 Mar; 452(2):90-5. PubMed ID: 19154776
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 19.