BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

154 related articles for article (PubMed ID: 27577574)

  • 1. Dehydroevodiamine•HCl Protects Against Memory Impairment and Cerebral Amyloid-β Production in Tg2576 Mice by Acting as a β-Secretase Inhibitor.
    Shin KY; Noh SJ; Park CH; Jeong YH; Chang KA; Yoo J; Kim HJ; Ha S; Kim HS; Park HJ; Lee JH; Moon C; Suh YH
    CNS Neurol Disord Drug Targets; 2016; 15(8):935-944. PubMed ID: 27577574
    [TBL] [Abstract][Full Text] [Related]  

  • 2. 4-O-methylhonokiol prevents memory impairment in the Tg2576 transgenic mice model of Alzheimer's disease via regulation of β-secretase activity.
    Lee YJ; Choi DY; Lee YK; Lee YM; Han SB; Kim YH; Kim KH; Nam SY; Lee BJ; Kang JK; Yun YW; Oh KW; Hong JT
    J Alzheimers Dis; 2012; 29(3):677-90. PubMed ID: 22330831
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Deletion of the cathepsin B gene improves memory deficits in a transgenic ALZHeimer's disease mouse model expressing AβPP containing the wild-type β-secretase site sequence.
    Kindy MS; Yu J; Zhu H; El-Amouri SS; Hook V; Hook GR
    J Alzheimers Dis; 2012; 29(4):827-40. PubMed ID: 22337825
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Beneficial effects of the β-secretase inhibitor GRL-8234 in 5XFAD Alzheimer's transgenic mice lessen during disease progression.
    Devi L; Tang J; Ohno M
    Curr Alzheimer Res; 2015; 12(1):13-21. PubMed ID: 25523425
    [TBL] [Abstract][Full Text] [Related]  

  • 5. 4-O-methylhonokiol attenuated memory impairment through modulation of oxidative damage of enzymes involving amyloid-β generation and accumulation in a mouse model of Alzheimer's disease.
    Choi IS; Lee YJ; Choi DY; Lee YK; Lee YH; Kim KH; Kim YH; Jeon YH; Kim EH; Han SB; Jung JK; Yun YP; Oh KW; Hwang DY; Hong JT
    J Alzheimers Dis; 2011; 27(1):127-41. PubMed ID: 21799245
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Ryanodine receptor blockade reduces amyloid-β load and memory impairments in Tg2576 mouse model of Alzheimer disease.
    Oulès B; Del Prete D; Greco B; Zhang X; Lauritzen I; Sevalle J; Moreno S; Paterlini-Bréchot P; Trebak M; Checler F; Benfenati F; Chami M
    J Neurosci; 2012 Aug; 32(34):11820-34. PubMed ID: 22915123
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Autophagy enhancer carbamazepine alleviates memory deficits and cerebral amyloid-β pathology in a mouse model of Alzheimer's disease.
    Li L; Zhang S; Zhang X; Li T; Tang Y; Liu H; Yang W; Le W
    Curr Alzheimer Res; 2013 May; 10(4):433-41. PubMed ID: 23305067
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Insulin-resistant brain state after intracerebroventricular streptozotocin injection exacerbates Alzheimer-like changes in Tg2576 AbetaPP-overexpressing mice.
    Plaschke K; Kopitz J; Siegelin M; Schliebs R; Salkovic-Petrisic M; Riederer P; Hoyer S
    J Alzheimers Dis; 2010; 19(2):691-704. PubMed ID: 20110613
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Berberine Alleviates Amyloid-Beta Pathology in the Brain of APP/PS1 Transgenic Mice via Inhibiting β/γ-Secretases Activity and Enhancing α-Secretases.
    Cai Z; Wang C; He W; Chen Y
    Curr Alzheimer Res; 2018; 15(11):1045-1052. PubMed ID: 29962345
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Acceleration of amyloidogenesis and memory impairment by estrogen deficiency through NF-κB dependent beta-secretase activation in presenilin 2 mutant mice.
    Hwang CJ; Park MH; Choi MK; Choi JS; Oh KW; Hwang DY; Han SB; Hong JT
    Brain Behav Immun; 2016 Mar; 53():113-122. PubMed ID: 26593275
    [TBL] [Abstract][Full Text] [Related]  

  • 11. O-linked β-N-acetylglucosaminidase inhibitor attenuates β-amyloid plaque and rescues memory impairment.
    Kim C; Nam DW; Park SY; Song H; Hong HS; Boo JH; Jung ES; Kim Y; Baek JY; Kim KS; Cho JW; Mook-Jung I
    Neurobiol Aging; 2013 Jan; 34(1):275-85. PubMed ID: 22503002
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Chronic Sleep Restriction Induces Cognitive Deficits and Cortical Beta-Amyloid Deposition in Mice via BACE1-Antisense Activation.
    Zhao HY; Wu HJ; He JL; Zhuang JH; Liu ZY; Huang LQ; Zhao ZX
    CNS Neurosci Ther; 2017 Mar; 23(3):233-240. PubMed ID: 28145081
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Dexamethasone and Aβ₂₅-₃₅ accelerate learning and memory impairments due to elevate amyloid precursor protein expression and neuronal apoptosis in 12-month male rats.
    Li WZ; Li WP; Huang DK; Kan HW; Wang X; Wu WY; Yin YY; Yao YY
    Behav Brain Res; 2012 Feb; 227(1):142-9. PubMed ID: 22061800
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Cryptotanshinone, a compound from Salvia miltiorrhiza modulates amyloid precursor protein metabolism and attenuates beta-amyloid deposition through upregulating alpha-secretase in vivo and in vitro.
    Mei Z; Zhang F; Tao L; Zheng W; Cao Y; Wang Z; Tang S; Le K; Chen S; Pi R; Liu P
    Neurosci Lett; 2009 Mar; 452(2):90-5. PubMed ID: 19154776
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Reduction of β-amyloid accumulation by reticulon 3 in transgenic mice.
    Araki W; Oda A; Motoki K; Hattori K; Itoh M; Yuasa S; Konishi Y; Shin RW; Tamaoka A; Ogino K
    Curr Alzheimer Res; 2013 Feb; 10(2):135-42. PubMed ID: 22742855
    [TBL] [Abstract][Full Text] [Related]  

  • 16. 1950 MHz Electromagnetic Fields Ameliorate Aβ Pathology in Alzheimer's Disease Mice.
    Jeong YJ; Kang GY; Kwon JH; Choi HD; Pack JK; Kim N; Lee YS; Lee HJ
    Curr Alzheimer Res; 2015; 12(5):481-92. PubMed ID: 26017559
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Amyloid-β protein (Aβ) Glu11 is the major β-secretase site of β-site amyloid-β precursor protein-cleaving enzyme 1(BACE1), and shifting the cleavage site to Aβ Asp1 contributes to Alzheimer pathogenesis.
    Deng Y; Wang Z; Wang R; Zhang X; Zhang S; Wu Y; Staufenbiel M; Cai F; Song W
    Eur J Neurosci; 2013 Jun; 37(12):1962-9. PubMed ID: 23773065
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Central and peripheral administration of antisense oligonucleotide targeting amyloid-β protein precursor improves learning and memory and reduces neuroinflammatory cytokines in Tg2576 (AβPPswe) mice.
    Farr SA; Erickson MA; Niehoff ML; Banks WA; Morley JE
    J Alzheimers Dis; 2014; 40(4):1005-16. PubMed ID: 24577464
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Amelioration of cognitive deficits in plaque-bearing Alzheimer's disease model mice through selective reduction of nascent soluble Aβ42 without affecting other Aβ pools.
    Mitani Y; Yarimizu J; Akashiba H; Shitaka Y; Ni K; Matsuoka N
    J Neurochem; 2013 May; 125(3):465-72. PubMed ID: 23240999
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Protective effect of n-butanol extract from Alpinia oxyphylla on learning and memory impairments.
    Shi SH; Zhao X; Liu AJ; Liu B; Li H; Wu B; Bi KS; Jia Y
    Physiol Behav; 2015 Feb; 139():13-20. PubMed ID: 25446210
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.