BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

151 related articles for article (PubMed ID: 27578312)

  • 1. Bacterial Cell Growth Inhibitors Targeting Undecaprenyl Diphosphate Synthase and Undecaprenyl Diphosphate Phosphatase.
    Wang Y; Desai J; Zhang Y; Malwal SR; Shin CJ; Feng X; Sun H; Liu G; Guo RT; Oldfield E
    ChemMedChem; 2016 Oct; 11(20):2311-2319. PubMed ID: 27578312
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Discovery and Characterization of a Class of Pyrazole Inhibitors of Bacterial Undecaprenyl Pyrophosphate Synthase.
    Concha N; Huang J; Bai X; Benowitz A; Brady P; Grady LC; Kryn LH; Holmes D; Ingraham K; Jin Q; Pothier Kaushansky L; McCloskey L; Messer JA; O'Keefe H; Patel A; Satz AL; Sinnamon RH; Schneck J; Skinner SR; Summerfield J; Taylor A; Taylor JD; Evindar G; Stavenger RA
    J Med Chem; 2016 Aug; 59(15):7299-304. PubMed ID: 27379833
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Structure, Function, and Inhibition of Staphylococcus aureus Heptaprenyl Diphosphate Synthase.
    Desai J; Liu YL; Wei H; Liu W; Ko TP; Guo RT; Oldfield E
    ChemMedChem; 2016 Sep; 11(17):1915-23. PubMed ID: 27457559
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Isoprenoid Biosynthesis Inhibitors Targeting Bacterial Cell Growth.
    Desai J; Wang Y; Wang K; Malwal SR; Oldfield E
    ChemMedChem; 2016 Oct; 11(19):2205-2215. PubMed ID: 27571880
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Antibacterial drug leads targeting isoprenoid biosynthesis.
    Zhu W; Zhang Y; Sinko W; Hensler ME; Olson J; Molohon KJ; Lindert S; Cao R; Li K; Wang K; Wang Y; Liu YL; Sankovsky A; de Oliveira CA; Mitchell DA; Nizet V; McCammon JA; Oldfield E
    Proc Natl Acad Sci U S A; 2013 Jan; 110(1):123-8. PubMed ID: 23248302
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Antibacterial drug leads: DNA and enzyme multitargeting.
    Zhu W; Wang Y; Li K; Gao J; Huang CH; Chen CC; Ko TP; Zhang Y; Guo RT; Oldfield E
    J Med Chem; 2015 Feb; 58(3):1215-27. PubMed ID: 25574764
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Undecaprenyl diphosphate synthase inhibitors: antibacterial drug leads.
    Sinko W; Wang Y; Zhu W; Zhang Y; Feixas F; Cox CL; Mitchell DA; Oldfield E; McCammon JA
    J Med Chem; 2014 Jul; 57(13):5693-701. PubMed ID: 24827744
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Non-bisphosphonate inhibitors of isoprenoid biosynthesis identified via computer-aided drug design.
    Durrant JD; Cao R; Gorfe AA; Zhu W; Li J; Sankovsky A; Oldfield E; McCammon JA
    Chem Biol Drug Des; 2011 Sep; 78(3):323-32. PubMed ID: 21696546
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Antagonism screen for inhibitors of bacterial cell wall biogenesis uncovers an inhibitor of undecaprenyl diphosphate synthase.
    Farha MA; Czarny TL; Myers CL; Worrall LJ; French S; Conrady DG; Wang Y; Oldfield E; Strynadka NC; Brown ED
    Proc Natl Acad Sci U S A; 2015 Sep; 112(35):11048-53. PubMed ID: 26283394
    [TBL] [Abstract][Full Text] [Related]  

  • 10. A Small-Molecule Screening Platform for the Discovery of Inhibitors of Undecaprenyl Diphosphate Synthase.
    Czarny TL; Brown ED
    ACS Infect Dis; 2016 Jul; 2(7):489-99. PubMed ID: 27626101
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Structural Insights into the Inhibition of Undecaprenyl Pyrophosphate Synthase from Gram-Positive Bacteria.
    Workman SD; Day J; Farha MA; El Zahed SS; Bon C; Brown ED; Organ MG; Strynadka NCJ
    J Med Chem; 2021 Sep; 64(18):13540-13550. PubMed ID: 34473495
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Discovery of Lipophilic Bisphosphonates That Target Bacterial Cell Wall and Quinone Biosynthesis.
    Malwal SR; Chen L; Hicks H; Qu F; Liu W; Shillo A; Law WX; Zhang J; Chandnani N; Han X; Zheng Y; Chen CC; Guo RT; AbdelKhalek A; Seleem MN; Oldfield E
    J Med Chem; 2019 Mar; 62(5):2564-2581. PubMed ID: 30730737
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Undecaprenyl diphosphate synthase, a cis-prenyltransferase synthesizing lipid carrier for bacterial cell wall biosynthesis.
    Teng KH; Liang PH
    Mol Membr Biol; 2012 Nov; 29(7):267-73. PubMed ID: 22471620
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Recent Advances in the Development of Undecaprenyl Pyrophosphate Synthase Inhibitors as Potential Antibacterials.
    Jukic M; Rozman K; Gobec S
    Curr Med Chem; 2016; 23(5):464-82. PubMed ID: 26718796
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Discovery of Prenyltransferase Inhibitors with
    Song J; Malwal SR; Baig N; Schurig-Briccio LA; Gao Z; Vaidya GS; Yang K; Abutaleb NS; Seleem MN; Gennis RB; Pogorelov TV; Oldfield E; Feng X
    ACS Infect Dis; 2020 Nov; 6(11):2979-2993. PubMed ID: 33085463
    [No Abstract]   [Full Text] [Related]  

  • 16. Synthesis and antimicrobial studies of hydrazone derivatives of 4-[3-(2,4-difluorophenyl)-4-formyl-1H-pyrazol-1-yl]benzoic acid and 4-[3-(3,4-difluorophenyl)-4-formyl-1H-pyrazol-1-yl]benzoic acid.
    Zakeyah AA; Whitt J; Duke C; Gilmore DF; Meeker DG; Smeltzer MS; Alam MA
    Bioorg Med Chem Lett; 2018 Sep; 28(17):2914-2919. PubMed ID: 30017319
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Synthesis and biological activity of isopentenyl diphosphate analogues.
    Scholte AA; Eubanks LM; Poulter CD; Vederas JC
    Bioorg Med Chem; 2004 Feb; 12(4):763-70. PubMed ID: 14759736
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Benzothioxalone derivatives as novel inhibitors of UDP-N-acetylglucosamine enolpyruvyl transferases (MurA and MurZ).
    Miller K; Dunsmore CJ; Leeds JA; Patching SG; Sachdeva M; Blake KL; Stubbings WJ; Simmons KJ; Henderson PJ; De Los Angeles J; Fishwick CW; Chopra I
    J Antimicrob Chemother; 2010 Dec; 65(12):2566-73. PubMed ID: 20861142
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Deciphering the metabolism of undecaprenyl-phosphate: the bacterial cell-wall unit carrier at the membrane frontier.
    Manat G; Roure S; Auger R; Bouhss A; Barreteau H; Mengin-Lecreulx D; Touzé T
    Microb Drug Resist; 2014 Jun; 20(3):199-214. PubMed ID: 24799078
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Discovery and structural characterization of an allosteric inhibitor of bacterial cis-prenyltransferase.
    Danley DE; Baima ET; Mansour M; Fennell KF; Chrunyk BA; Mueller JP; Liu S; Qiu X
    Protein Sci; 2015 Jan; 24(1):20-6. PubMed ID: 25287857
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.