263 related articles for article (PubMed ID: 27580159)
1. Rags to riches: Amino acid sensing by the Rag GTPases in health and disease.
Brady OA; Diab HI; Puertollano R
Small GTPases; 2016 Oct; 7(4):197-206. PubMed ID: 27580159
[TBL] [Abstract][Full Text] [Related]
2. Rag GTPases mediate amino acid-dependent recruitment of TFEB and MITF to lysosomes.
Martina JA; Puertollano R
J Cell Biol; 2013 Feb; 200(4):475-91. PubMed ID: 23401004
[TBL] [Abstract][Full Text] [Related]
3. Amino acids activate mammalian target of rapamycin (mTOR) complex 1 without changing Rag GTPase guanyl nucleotide charging.
Oshiro N; Rapley J; Avruch J
J Biol Chem; 2014 Jan; 289(5):2658-74. PubMed ID: 24337580
[TBL] [Abstract][Full Text] [Related]
4. Rheb and Rags come together at the lysosome to activate mTORC1.
Groenewoud MJ; Zwartkruis FJ
Biochem Soc Trans; 2013 Aug; 41(4):951-5. PubMed ID: 23863162
[TBL] [Abstract][Full Text] [Related]
5. Requirement for lysosomal localization of mTOR for its activation differs between leucine and other amino acids.
Averous J; Lambert-Langlais S; Carraro V; Gourbeyre O; Parry L; B'Chir W; Muranishi Y; Jousse C; Bruhat A; Maurin AC; Proud CG; Fafournoux P
Cell Signal; 2014 Sep; 26(9):1918-27. PubMed ID: 24793303
[TBL] [Abstract][Full Text] [Related]
6. Recruitment of folliculin to lysosomes supports the amino acid-dependent activation of Rag GTPases.
Petit CS; Roczniak-Ferguson A; Ferguson SM
J Cell Biol; 2013 Sep; 202(7):1107-22. PubMed ID: 24081491
[TBL] [Abstract][Full Text] [Related]
7. Disruption of the Rag-Ragulator Complex by c17orf59 Inhibits mTORC1.
Schweitzer LD; Comb WC; Bar-Peled L; Sabatini DM
Cell Rep; 2015 Sep; 12(9):1445-55. PubMed ID: 26299971
[TBL] [Abstract][Full Text] [Related]
8. Regulation of mTORC1 by the Rag GTPases.
Lama-Sherpa TD; Jeong MH; Jewell JL
Biochem Soc Trans; 2023 Apr; 51(2):655-664. PubMed ID: 36929165
[TBL] [Abstract][Full Text] [Related]
9. Sestrins function as guanine nucleotide dissociation inhibitors for Rag GTPases to control mTORC1 signaling.
Peng M; Yin N; Li MO
Cell; 2014 Sep; 159(1):122-133. PubMed ID: 25259925
[TBL] [Abstract][Full Text] [Related]
10. Rag GTPase in amino acid signaling.
Kim J; Kim E
Amino Acids; 2016 Apr; 48(4):915-928. PubMed ID: 26781224
[TBL] [Abstract][Full Text] [Related]
11. Amino acid signalling upstream of mTOR.
Jewell JL; Russell RC; Guan KL
Nat Rev Mol Cell Biol; 2013 Mar; 14(3):133-9. PubMed ID: 23361334
[TBL] [Abstract][Full Text] [Related]
12. Regulation of mTORC1 by amino acids.
Bar-Peled L; Sabatini DM
Trends Cell Biol; 2014 Jul; 24(7):400-6. PubMed ID: 24698685
[TBL] [Abstract][Full Text] [Related]
13. The folliculin tumor suppressor is a GAP for the RagC/D GTPases that signal amino acid levels to mTORC1.
Tsun ZY; Bar-Peled L; Chantranupong L; Zoncu R; Wang T; Kim C; Spooner E; Sabatini DM
Mol Cell; 2013 Nov; 52(4):495-505. PubMed ID: 24095279
[TBL] [Abstract][Full Text] [Related]
14. The amino acid transporter SLC36A4 regulates the amino acid pool in retinal pigmented epithelial cells and mediates the mechanistic target of rapamycin, complex 1 signaling.
Shang P; Valapala M; Grebe R; Hose S; Ghosh S; Bhutto IA; Handa JT; Lutty GA; Lu L; Wan J; Qian J; Sergeev Y; Puertollano R; Zigler JS; Xu GT; Sinha D
Aging Cell; 2017 Apr; 16(2):349-359. PubMed ID: 28083894
[TBL] [Abstract][Full Text] [Related]
15. Amino Acid-Dependent mTORC1 Regulation by the Lysosomal Membrane Protein SLC38A9.
Jung J; Genau HM; Behrends C
Mol Cell Biol; 2015 Jul; 35(14):2479-94. PubMed ID: 25963655
[TBL] [Abstract][Full Text] [Related]
16. The nutrient-responsive transcription factor TFE3 promotes autophagy, lysosomal biogenesis, and clearance of cellular debris.
Martina JA; Diab HI; Lishu L; Jeong-A L; Patange S; Raben N; Puertollano R
Sci Signal; 2014 Jan; 7(309):ra9. PubMed ID: 24448649
[TBL] [Abstract][Full Text] [Related]
17. A Tumor suppressor complex with GAP activity for the Rag GTPases that signal amino acid sufficiency to mTORC1.
Bar-Peled L; Chantranupong L; Cherniack AD; Chen WW; Ottina KA; Grabiner BC; Spear ED; Carter SL; Meyerson M; Sabatini DM
Science; 2013 May; 340(6136):1100-6. PubMed ID: 23723238
[TBL] [Abstract][Full Text] [Related]
18. Regulation of TORC1 in response to amino acid starvation via lysosomal recruitment of TSC2.
Demetriades C; Doumpas N; Teleman AA
Cell; 2014 Feb; 156(4):786-99. PubMed ID: 24529380
[TBL] [Abstract][Full Text] [Related]
19. Ragulator-Rag complex targets mTORC1 to the lysosomal surface and is necessary for its activation by amino acids.
Sancak Y; Bar-Peled L; Zoncu R; Markhard AL; Nada S; Sabatini DM
Cell; 2010 Apr; 141(2):290-303. PubMed ID: 20381137
[TBL] [Abstract][Full Text] [Related]
20. A lysosome-to-nucleus signalling mechanism senses and regulates the lysosome via mTOR and TFEB.
Settembre C; Zoncu R; Medina DL; Vetrini F; Erdin S; Erdin S; Huynh T; Ferron M; Karsenty G; Vellard MC; Facchinetti V; Sabatini DM; Ballabio A
EMBO J; 2012 Mar; 31(5):1095-108. PubMed ID: 22343943
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
