BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

220 related articles for article (PubMed ID: 27585860)

  • 1. Clonal dynamics following p53 loss of heterozygosity in Kras-driven cancers.
    Muzumdar MD; Dorans KJ; Chung KM; Robbins R; Tammela T; Gocheva V; Li CM; Jacks T
    Nat Commun; 2016 Sep; 7():12685. PubMed ID: 27585860
    [TBL] [Abstract][Full Text] [Related]  

  • 2. A genetically engineered mouse model developing rapid progressive pancreatic ductal adenocarcinoma.
    Yamaguchi T; Ikehara S; Nakanishi H; Ikehara Y
    J Pathol; 2014 Oct; 234(2):228-38. PubMed ID: 25042889
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Nicotine promotes initiation and progression of KRAS-induced pancreatic cancer via Gata6-dependent dedifferentiation of acinar cells in mice.
    Hermann PC; Sancho P; Cañamero M; Martinelli P; Madriles F; Michl P; Gress T; de Pascual R; Gandia L; Guerra C; Barbacid M; Wagner M; Vieira CR; Aicher A; Real FX; Sainz B; Heeschen C
    Gastroenterology; 2014 Nov; 147(5):1119-33.e4. PubMed ID: 25127677
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Wild-Type Hras Suppresses the Earliest Stages of Tumorigenesis in a Genetically Engineered Mouse Model of Pancreatic Cancer.
    Weyandt JD; Lampson BL; Tang S; Mastrodomenico M; Cardona DM; Counter CM
    PLoS One; 2015; 10(10):e0140253. PubMed ID: 26452271
    [TBL] [Abstract][Full Text] [Related]  

  • 5. CDKN2B deletion is essential for pancreatic cancer development instead of unmeaningful co-deletion due to juxtaposition to CDKN2A.
    Tu Q; Hao J; Zhou X; Yan L; Dai H; Sun B; Yang D; An S; Lv L; Jiao B; Chen C; Lai R; Shi P; Zhao X
    Oncogene; 2018 Jan; 37(1):128-138. PubMed ID: 28892048
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Loss of Activin Receptor Type 1B Accelerates Development of Intraductal Papillary Mucinous Neoplasms in Mice With Activated KRAS.
    Qiu W; Tang SM; Lee S; Turk AT; Sireci AN; Qiu A; Rose C; Xie C; Kitajewski J; Wen HJ; Crawford HC; Sims PA; Hruban RH; Remotti HE; Su GH
    Gastroenterology; 2016 Jan; 150(1):218-228.e12. PubMed ID: 26408346
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Dynamic landscape of pancreatic carcinogenesis reveals early molecular networks of malignancy.
    Kong B; Bruns P; Behler NA; Chang L; Schlitter AM; Cao J; Gewies A; Ruland J; Fritzsche S; Valkovskaya N; Jian Z; Regel I; Raulefs S; Irmler M; Beckers J; Friess H; Erkan M; Mueller NS; Roth S; Hackert T; Esposito I; Theis FJ; Kleeff J; Michalski CW
    Gut; 2018 Jan; 67(1):146-156. PubMed ID: 27646934
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Mutant p53R270H drives altered metabolism and increased invasion in pancreatic ductal adenocarcinoma.
    Schofield HK; Zeller J; Espinoza C; Halbrook CJ; Del Vecchio A; Magnuson B; Fabo T; Cali Daylan AE; Kovalenko I; Lee HJ; Yan W; Feng Y; Karim SA; Kremer DM; Kumar-Sinha C; Lyssiotis CA; Ljungman M; Morton JP; Galbán S; Fearon ER; Pasca di Magliano M
    JCI Insight; 2018 Jan; 3(2):. PubMed ID: 29367463
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Oncogenic KRas suppresses inflammation-associated senescence of pancreatic ductal cells.
    Lee KE; Bar-Sagi D
    Cancer Cell; 2010 Nov; 18(5):448-58. PubMed ID: 21075310
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Reconstituting development of pancreatic intraepithelial neoplasia from primary human pancreas duct cells.
    Lee J; Snyder ER; Liu Y; Gu X; Wang J; Flowers BM; Kim YJ; Park S; Szot GL; Hruban RH; Longacre TA; Kim SK
    Nat Commun; 2017 Mar; 8():14686. PubMed ID: 28272465
    [TBL] [Abstract][Full Text] [Related]  

  • 11. The acinar regulator Gata6 suppresses KrasG12V-driven pancreatic tumorigenesis in mice.
    Martinelli P; Madriles F; Cañamero M; Pau EC; Pozo ND; Guerra C; Real FX
    Gut; 2016 Mar; 65(3):476-86. PubMed ID: 25596178
    [TBL] [Abstract][Full Text] [Related]  

  • 12. p53 mutations cooperate with oncogenic Kras to promote adenocarcinoma from pancreatic ductal cells.
    Bailey JM; Hendley AM; Lafaro KJ; Pruski MA; Jones NC; Alsina J; Younes M; Maitra A; McAllister F; Iacobuzio-Donahue CA; Leach SD
    Oncogene; 2016 Aug; 35(32):4282-8. PubMed ID: 26592447
    [TBL] [Abstract][Full Text] [Related]  

  • 13. A human cancer xenograft model utilizing normal pancreatic duct epithelial cells conditionally transformed with defined oncogenes.
    Inagawa Y; Yamada K; Yugawa T; Ohno S; Hiraoka N; Esaki M; Shibata T; Aoki K; Saya H; Kiyono T
    Carcinogenesis; 2014 Aug; 35(8):1840-6. PubMed ID: 24858378
    [TBL] [Abstract][Full Text] [Related]  

  • 14. p53 status determines the role of autophagy in pancreatic tumour development.
    Rosenfeldt MT; O'Prey J; Morton JP; Nixon C; MacKay G; Mrowinska A; Au A; Rai TS; Zheng L; Ridgway R; Adams PD; Anderson KI; Gottlieb E; Sansom OJ; Ryan KM
    Nature; 2013 Dec; 504(7479):296-300. PubMed ID: 24305049
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Molecular Characteristics of Pancreatic Ductal Adenocarcinomas with High-Grade Pancreatic Intraepithelial Neoplasia (PanIN) Are Different from Those without High-Grade PanIN.
    Miyazaki T; Ohishi Y; Miyasaka Y; Oda Y; Aishima S; Ozono K; Abe A; Nagai E; Nakamura M; Oda Y
    Pathobiology; 2017; 84(4):192-201. PubMed ID: 28291966
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Genetics and Biology of Pancreatic Ductal Adenocarcinoma.
    Dunne RF; Hezel AF
    Hematol Oncol Clin North Am; 2015 Aug; 29(4):595-608. PubMed ID: 26226899
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Evolution and dynamics of pancreatic cancer progression.
    Yachida S; Iacobuzio-Donahue CA
    Oncogene; 2013 Nov; 32(45):5253-60. PubMed ID: 23416985
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Important role of Nfkb2 in the Kras
    Hassan Z; Schneeweis C; Wirth M; Müller S; Geismann C; Neuß T; Steiger K; Krämer OH; Schmid RM; Rad R; Arlt A; Reichert M; Saur D; Schneider G
    Pancreatology; 2021 Aug; 21(5):912-919. PubMed ID: 33824054
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Loss of Somatostatin Receptor Subtype 2 Promotes Growth of KRAS-Induced Pancreatic Tumors in Mice by Activating PI3K Signaling and Overexpression of CXCL16.
    Chalabi-Dchar M; Cassant-Sourdy S; Duluc C; Fanjul M; Lulka H; Samain R; Roche C; Breibach F; Delisle MB; Poupot M; Dufresne M; Shimaoka T; Yonehara S; Mathonnet M; Pyronnet S; Bousquet C
    Gastroenterology; 2015 Jun; 148(7):1452-65. PubMed ID: 25683115
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Lunatic Fringe is a potent tumor suppressor in Kras-initiated pancreatic cancer.
    Zhang S; Chung WC; Xu K
    Oncogene; 2016 May; 35(19):2485-95. PubMed ID: 26279302
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.