BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

301 related articles for article (PubMed ID: 27589351)

  • 1. Characterizing monoclonal antibody formulations in arginine glutamate solutions using
    Kheddo P; Cliff MJ; Uddin S; van der Walle CF; Golovanov AP
    MAbs; 2016 Oct; 8(7):1245-1258. PubMed ID: 27589351
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Investigating Liquid-Liquid Phase Separation of a Monoclonal Antibody Using Solution-State NMR Spectroscopy: Effect of Arg·Glu and Arg·HCl.
    Kheddo P; Bramham JE; Dearman RJ; Uddin S; van der Walle CF; Golovanov AP
    Mol Pharm; 2017 Aug; 14(8):2852-2860. PubMed ID: 28614662
    [TBL] [Abstract][Full Text] [Related]  

  • 3. NMR spectroscopy as a characterization tool enabling biologics formulation development.
    Ma J; Pathirana C; Liu DQ; Miller SA
    J Pharm Biomed Anal; 2023 Jan; 223():115110. PubMed ID: 36308923
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Viscosity-Lowering Effect of Amino Acids and Salts on Highly Concentrated Solutions of Two IgG1 Monoclonal Antibodies.
    Wang S; Zhang N; Hu T; Dai W; Feng X; Zhang X; Qian F
    Mol Pharm; 2015 Dec; 12(12):4478-87. PubMed ID: 26528726
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Stability of a high-concentration monoclonal antibody solution produced by liquid-liquid phase separation.
    Bramham JE; Davies SA; Podmore A; Golovanov AP
    MAbs; 2021; 13(1):1940666. PubMed ID: 34225583
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Modulation of the Hydration Water Around Monoclonal Antibodies on Addition of Excipients Detected by Terahertz Time-Domain Spectroscopy.
    Wallace VP; Ferachou D; Ke P; Day K; Uddin S; Casas-Finet J; Van Der Walle CF; Falconer RJ; Zeitler JA
    J Pharm Sci; 2015 Dec; 104(12):4025-4033. PubMed ID: 26344202
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Improving Viscosity and Stability of a Highly Concentrated Monoclonal Antibody Solution with Concentrated Proline.
    Hung JJ; Dear BJ; Dinin AK; Borwankar AU; Mehta SK; Truskett TT; Johnston KP
    Pharm Res; 2018 Apr; 35(7):133. PubMed ID: 29713822
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Elucidating the weak protein-protein interaction mechanisms behind the liquid-liquid phase separation of a mAb solution by different types of additives.
    Wu G; Wang S; Tian Z; Zhang N; Sheng H; Dai W; Qian F
    Eur J Pharm Biopharm; 2017 Nov; 120():1-8. PubMed ID: 28754261
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Intermolecular Interactions and the Viscosity of Highly Concentrated Monoclonal Antibody Solutions.
    Binabaji E; Ma J; Zydney AL
    Pharm Res; 2015 Sep; 32(9):3102-9. PubMed ID: 25832501
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Profiling formulated monoclonal antibodies by (1)H NMR spectroscopy.
    Poppe L; Jordan JB; Lawson K; Jerums M; Apostol I; Schnier PD
    Anal Chem; 2013 Oct; 85(20):9623-9. PubMed ID: 24006877
    [TBL] [Abstract][Full Text] [Related]  

  • 11. The effect of arginine glutamate on the stability of monoclonal antibodies in solution.
    Kheddo P; Tracka M; Armer J; Dearman RJ; Uddin S; van der Walle CF; Golovanov AP
    Int J Pharm; 2014 Oct; 473(1-2):126-33. PubMed ID: 24992318
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Hydrogen-deuterium exchange mass spectrometry as an emerging analytical tool for stabilization and formulation development of therapeutic monoclonal antibodies.
    Majumdar R; Middaugh CR; Weis DD; Volkin DB
    J Pharm Sci; 2015 Feb; 104(2):327-45. PubMed ID: 25354868
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Stability of buffer-free freeze-dried formulations: A feasibility study of a monoclonal antibody at high protein concentrations.
    Garidel P; Pevestorf B; Bahrenburg S
    Eur J Pharm Biopharm; 2015 Nov; 97(Pt A):125-39. PubMed ID: 26455339
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Bulky Polar Additives That Greatly Reduce the Viscosity of Concentrated Solutions of Therapeutic Monoclonal Antibodies.
    Larson AM; Weight AK; Love K; Bonificio A; Wescott CR; Klibanov AM
    J Pharm Sci; 2017 May; 106(5):1211-1217. PubMed ID: 28137697
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Effects of Histidine and Sucrose on the Biophysical Properties of a Monoclonal Antibody.
    Baek Y; Singh N; Arunkumar A; Zydney AL
    Pharm Res; 2017 Mar; 34(3):629-639. PubMed ID: 28035628
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Novel salts of dipicolinic acid as viscosity modifiers for high concentration antibody solutions.
    Ke P; Batalha IL; Dobson A; Tejeda-Montes E; Ekizoglou S; Christie G; McCabe J; van der Walle CF
    Int J Pharm; 2018 Sep; 548(1):682-688. PubMed ID: 30009985
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Reversible self-association increases the viscosity of a concentrated monoclonal antibody in aqueous solution.
    Liu J; Nguyen MD; Andya JD; Shire SJ
    J Pharm Sci; 2005 Sep; 94(9):1928-40. PubMed ID: 16052543
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Caffeine as a Viscosity Reducer for Highly Concentrated Monoclonal Antibody Solutions.
    Zeng Y; Tran T; Wuthrich P; Naik S; Davagnino J; Greene DG; Mahoney RP; Soane DS
    J Pharm Sci; 2021 Nov; 110(11):3594-3604. PubMed ID: 34181992
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Both Reversible Self-Association and Structural Changes Underpin Molecular Viscoelasticity of mAb Solutions.
    Sarangapani PS; Weaver J; Parupudi A; Besong TMD; Adams GG; Harding SE; Manikwar P; Castellanos MM; Bishop SM; Pathak JA
    J Pharm Sci; 2016 Dec; 105(12):3496-3506. PubMed ID: 27793346
    [TBL] [Abstract][Full Text] [Related]  

  • 20. An Approach to Mitigate Particle Formation on the Dilution of a Monoclonal Antibody Drug Product in an IV Administration Fluid.
    Zheng S; Adams M; Mantri RV
    J Pharm Sci; 2016 Mar; 105(3):1349-50. PubMed ID: 26886343
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 16.