BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

190 related articles for article (PubMed ID: 27590338)

  • 1. Ser/Thr Phosphorylation Regulates the Fatty Acyl-AMP Ligase Activity of FadD32, an Essential Enzyme in Mycolic Acid Biosynthesis.
    Le NH; Molle V; Eynard N; Miras M; Stella A; Bardou F; Galandrin S; Guillet V; André-Leroux G; Bellinzoni M; Alzari P; Mourey L; Burlet-Schiltz O; Daffé M; Marrakchi H
    J Biol Chem; 2016 Oct; 291(43):22793-22805. PubMed ID: 27590338
    [TBL] [Abstract][Full Text] [Related]  

  • 2. The acyl-AMP ligase FadD32 and AccD4-containing acyl-CoA carboxylase are required for the synthesis of mycolic acids and essential for mycobacterial growth: identification of the carboxylation product and determination of the acyl-CoA carboxylase components.
    Portevin D; de Sousa-D'Auria C; Montrozier H; Houssin C; Stella A; Lanéelle MA; Bardou F; Guilhot C; Daffé M
    J Biol Chem; 2005 Mar; 280(10):8862-74. PubMed ID: 15632194
    [TBL] [Abstract][Full Text] [Related]  

  • 3. The Pks13/FadD32 crosstalk for the biosynthesis of mycolic acids in Mycobacterium tuberculosis.
    Gavalda S; Léger M; van der Rest B; Stella A; Bardou F; Montrozier H; Chalut C; Burlet-Schiltz O; Marrakchi H; Daffé M; Quémard A
    J Biol Chem; 2009 Jul; 284(29):19255-64. PubMed ID: 19436070
    [TBL] [Abstract][Full Text] [Related]  

  • 4. The dual function of the Mycobacterium tuberculosis FadD32 required for mycolic acid biosynthesis.
    Léger M; Gavalda S; Guillet V; van der Rest B; Slama N; Montrozier H; Mourey L; Quémard A; Daffé M; Marrakchi H
    Chem Biol; 2009 May; 16(5):510-9. PubMed ID: 19477415
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Insight into Structure-Function Relationships and Inhibition of the Fatty Acyl-AMP Ligase (FadD32) Orthologs from Mycobacteria.
    Guillet V; Galandrin S; Maveyraud L; Ladevèze S; Mariaule V; Bon C; Eynard N; Daffé M; Marrakchi H; Mourey L
    J Biol Chem; 2016 Apr; 291(15):7973-89. PubMed ID: 26900152
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Phosphorylation of the Mycobacterium tuberculosis beta-ketoacyl-acyl carrier protein reductase MabA regulates mycolic acid biosynthesis.
    Veyron-Churlet R; Zanella-Cléon I; Cohen-Gonsaud M; Molle V; Kremer L
    J Biol Chem; 2010 Apr; 285(17):12714-25. PubMed ID: 20178986
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Assay development for identifying inhibitors of the mycobacterial FadD32 activity.
    Galandrin S; Guillet V; Rane RS; Léger M; N R; Eynard N; Das K; Balganesh TS; Mourey L; Daffé M; Marrakchi H
    J Biomol Screen; 2013 Jun; 18(5):576-87. PubMed ID: 23364516
    [TBL] [Abstract][Full Text] [Related]  

  • 8. The Mycobacterium tuberculosis beta-ketoacyl-acyl carrier protein synthase III activity is inhibited by phosphorylation on a single threonine residue.
    Veyron-Churlet R; Molle V; Taylor RC; Brown AK; Besra GS; Zanella-Cléon I; Fütterer K; Kremer L
    J Biol Chem; 2009 Mar; 284(10):6414-24. PubMed ID: 19074144
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Crystal structure of FadD32, an enzyme essential for mycolic acid biosynthesis in mycobacteria.
    Li W; Gu S; Fleming J; Bi L
    Sci Rep; 2015 Dec; 5():15493. PubMed ID: 26628098
    [TBL] [Abstract][Full Text] [Related]  

  • 10. The Molecular Genetics of Mycolic Acid Biosynthesis.
    PaweŁczyk J; Kremer L
    Microbiol Spectr; 2014 Aug; 2(4):MGM2-0003-2013. PubMed ID: 26104214
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Phosphorylation of mycobacterial PcaA inhibits mycolic acid cyclopropanation: consequences for intracellular survival and for phagosome maturation block.
    Corrales RM; Molle V; Leiba J; Mourey L; de Chastellier C; Kremer L
    J Biol Chem; 2012 Jul; 287(31):26187-99. PubMed ID: 22621931
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Phosphorylation of KasB regulates virulence and acid-fastness in Mycobacterium tuberculosis.
    Vilchèze C; Molle V; Carrère-Kremer S; Leiba J; Mourey L; Shenai S; Baronian G; Tufariello J; Hartman T; Veyron-Churlet R; Trivelli X; Tiwari S; Weinrick B; Alland D; Guérardel Y; Jacobs WR; Kremer L
    PLoS Pathog; 2014 May; 10(5):e1004115. PubMed ID: 24809459
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Antituberculosis thiophenes define a requirement for Pks13 in mycolic acid biosynthesis.
    Wilson R; Kumar P; Parashar V; Vilchèze C; Veyron-Churlet R; Freundlich JS; Barnes SW; Walker JR; Szymonifka MJ; Marchiano E; Shenai S; Colangeli R; Jacobs WR; Neiditch MB; Kremer L; Alland D
    Nat Chem Biol; 2013 Aug; 9(8):499-506. PubMed ID: 23770708
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Diarylcoumarins inhibit mycolic acid biosynthesis and kill Mycobacterium tuberculosis by targeting FadD32.
    Stanley SA; Kawate T; Iwase N; Shimizu M; Clatworthy AE; Kazyanskaya E; Sacchettini JC; Ioerger TR; Siddiqi NA; Minami S; Aquadro JA; Grant SS; Rubin EJ; Hung DT
    Proc Natl Acad Sci U S A; 2013 Jul; 110(28):11565-70. PubMed ID: 23798446
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Structure of the Essential
    Kuhn ML; Alexander E; Minasov G; Page HJ; Warwrzak Z; Shuvalova L; Flores KJ; Wilson DJ; Shi C; Aldrich CC; Anderson WF
    ACS Infect Dis; 2016 Aug; 2(8):579-591. PubMed ID: 27547819
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Structure and dynamics of the essential endogenous mycobacterial polyketide synthase Pks13.
    Kim SK; Dickinson MS; Finer-Moore J; Guan Z; Kaake RM; Echeverria I; Chen J; Pulido EH; Sali A; Krogan NJ; Rosenberg OS; Stroud RM
    Nat Struct Mol Biol; 2023 Mar; 30(3):296-308. PubMed ID: 36782050
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Solution structure of the type I polyketide synthase Pks13 from Mycobacterium tuberculosis.
    Bon C; Cabantous S; Julien S; Guillet V; Chalut C; Rima J; Brison Y; Malaga W; Sanchez-Dafun A; Gavalda S; Quémard A; Marcoux J; Waldo GS; Guilhot C; Mourey L
    BMC Biol; 2022 Jun; 20(1):147. PubMed ID: 35729566
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Kinase Targets for Mycolic Acid Biosynthesis in Mycobacterium tuberculosis.
    Alsayed SSR; Beh CC; Foster NR; Payne AD; Yu Y; Gunosewoyo H
    Curr Mol Pharmacol; 2019; 12(1):27-49. PubMed ID: 30360731
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Phosphorylation of InhA inhibits mycolic acid biosynthesis and growth of Mycobacterium tuberculosis.
    Molle V; Gulten G; Vilchèze C; Veyron-Churlet R; Zanella-Cléon I; Sacchettini JC; Jacobs WR; Kremer L
    Mol Microbiol; 2010 Dec; 78(6):1591-605. PubMed ID: 21143326
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Multi-omics Investigation into the Mechanism of Action of an Anti-tubercular Fatty Acid Analogue.
    Sakallioglu IT; Maroli AS; De Lima Leite A; Marshall DD; Evans BW; Zinniel DK; Dussault PH; Barletta RG; Powers R
    J Am Chem Soc; 2022 Nov; 144(46):21157-21173. PubMed ID: 36367461
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.