These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

211 related articles for article (PubMed ID: 27591792)

  • 21. Antibody humanization by redesign of complementarity-determining region residues proximate to the acceptor framework.
    Hanf KJ; Arndt JW; Chen LL; Jarpe M; Boriack-Sjodin PA; Li Y; van Vlijmen HW; Pepinsky RB; Simon KJ; Lugovskoy A
    Methods; 2014 Jan; 65(1):68-76. PubMed ID: 23816785
    [TBL] [Abstract][Full Text] [Related]  

  • 22. The critical role of arginine residues in the binding of human monoclonal antibodies to cardiolipin.
    Giles I; Lambrianides N; Latchman D; Chen P; Chukwuocha R; Isenberg D; Rahman A
    Arthritis Res Ther; 2005; 7(1):R47-56. PubMed ID: 15642142
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Conformational analysis of the first observed non-proline cis-peptide bond occurring within the complementarity determining region (CDR) of an antibody.
    Bates PA; Dokurno P; Freemont PS; Sternberg MJ
    J Mol Biol; 1998 Dec; 284(3):549-55. PubMed ID: 9826497
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Do antibody CDR loops change conformation upon binding?
    Liu C; Denzler LM; Hood OEC; Martin ACR
    MAbs; 2024; 16(1):2322533. PubMed ID: 38477253
    [TBL] [Abstract][Full Text] [Related]  

  • 25. A potential antibody repertoire diversification mechanism through tyrosine sulfation for biotherapeutics engineering and production.
    Zhong X; D'Antona AM
    Front Immunol; 2022; 13():1072702. PubMed ID: 36569848
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Multi-constraint computational design suggests that native sequences of germline antibody H3 loops are nearly optimal for conformational flexibility.
    Babor M; Kortemme T
    Proteins; 2009 Jun; 75(4):846-58. PubMed ID: 19194863
    [TBL] [Abstract][Full Text] [Related]  

  • 27. Antibody CDR loops as ensembles in solution vs. canonical clusters from X-ray structures.
    Fernández-Quintero ML; Heiss MC; Pomarici ND; Math BA; Liedl KR
    MAbs; 2020; 12(1):1744328. PubMed ID: 32264741
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Characterizing the Diversity of the CDR-H3 Loop Conformational Ensembles in Relationship to Antibody Binding Properties.
    Fernández-Quintero ML; Loeffler JR; Kraml J; Kahler U; Kamenik AS; Liedl KR
    Front Immunol; 2018; 9():3065. PubMed ID: 30666252
    [TBL] [Abstract][Full Text] [Related]  

  • 29. A new clustering of antibody CDR loop conformations.
    North B; Lehmann A; Dunbrack RL
    J Mol Biol; 2011 Feb; 406(2):228-56. PubMed ID: 21035459
    [TBL] [Abstract][Full Text] [Related]  

  • 30. Revisiting antibody modeling assessment for CDR-H3 loop.
    Nishigami H; Kamiya N; Nakamura H
    Protein Eng Des Sel; 2016 Nov; 29(11):477-484. PubMed ID: 27515703
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Hiding in plain sight: structure and sequence analysis reveals the importance of the antibody DE loop for antibody-antigen binding.
    Kelow SP; Adolf-Bryfogle J; Dunbrack RL
    MAbs; 2020; 12(1):1840005. PubMed ID: 33180672
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Restricted diversity of antigen binding residues of antibodies revealed by computational alanine scanning of 227 antibody-antigen complexes.
    Robin G; Sato Y; Desplancq D; Rochel N; Weiss E; Martineau P
    J Mol Biol; 2014 Nov; 426(22):3729-3743. PubMed ID: 25174334
    [TBL] [Abstract][Full Text] [Related]  

  • 33. X-ray structures of the antigen-binding domains from three variants of humanized anti-p185HER2 antibody 4D5 and comparison with molecular modeling.
    Eigenbrot C; Randal M; Presta L; Carter P; Kossiakoff AA
    J Mol Biol; 1993 Feb; 229(4):969-95. PubMed ID: 8095303
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Ab initio structure prediction of the antibody hypervariable H3 loop.
    Zhu K; Day T
    Proteins; 2013 Jun; 81(6):1081-9. PubMed ID: 23255066
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Framework residues 71 and 93 of the chimeric B72.3 antibody are major determinants of the conformation of heavy-chain hypervariable loops.
    Xiang J; Sha Y; Jia Z; Prasad L; Delbaere LT
    J Mol Biol; 1995 Oct; 253(3):385-90. PubMed ID: 7473721
    [TBL] [Abstract][Full Text] [Related]  

  • 36. Conformational sampling of CDR-H3 in antibodies by multicanonical molecular dynamics simulation.
    Shirai H; Nakajima N; Higo J; Kidera A; Nakamura H
    J Mol Biol; 1998 May; 278(2):481-96. PubMed ID: 9571065
    [TBL] [Abstract][Full Text] [Related]  

  • 37. Molecular dynamics simulation of a high-affinity antibody-protein complex: the binding site is a mosaic of locally flexible and preorganized rigid regions.
    Sinha N; Smith-Gill SJ
    Cell Biochem Biophys; 2005; 43(2):253-73. PubMed ID: 16049350
    [TBL] [Abstract][Full Text] [Related]  

  • 38. Decomposing Dynamical Couplings in Mutated scFv Antibody Fragments into Stabilizing and Destabilizing Effects.
    Ettayapuram Ramaprasad AS; Uddin S; Casas-Finet J; Jacobs DJ
    J Am Chem Soc; 2017 Dec; 139(48):17508-17517. PubMed ID: 29139290
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Combinatorial mutagenesis with alternative CDR-L1 and -H2 loop lengths contributes to affinity maturation of antibodies.
    Brockmann EC; Pyykkö M; Hannula H; Khan K; Lamminmäki U; Huovinen T
    N Biotechnol; 2021 Jan; 60():173-182. PubMed ID: 33039698
    [TBL] [Abstract][Full Text] [Related]  

  • 40. Humanization of rabbit monoclonal antibodies via grafting combined Kabat/IMGT/Paratome complementarity-determining regions: Rationale and examples.
    Zhang YF; Ho M
    MAbs; 2017 Apr; 9(3):419-429. PubMed ID: 28165915
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 11.