BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

135 related articles for article (PubMed ID: 27592826)

  • 1. [Efficient Approaches to S-alkyl-N-alkylisothioureas and Application to Novel Histamine H3R Antagonists].
    Yoneyama H; Yamamoto D; Yamatodani A; Harusawa S
    Yakugaku Zasshi; 2016; 136(9):1217-32. PubMed ID: 27592826
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Synthesis and evaluation of N-alkyl-S-[3-(piperidin-1-yl)propyl]isothioureas: high affinity and human/rat species-selective histamine H(3) receptor antagonists.
    Harusawa S; Sawada K; Magata T; Yoneyama H; Araki L; Usami Y; Hatano K; Yamamoto K; Yamamoto D; Yamatodani A
    Bioorg Med Chem Lett; 2013 Dec; 23(23):6415-20. PubMed ID: 24140447
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Efficient approaches to S-alkyl-N-alkylisothioureas: syntheses of histamine H3 antagonist clobenpropit and its analogues.
    Yoneyama H; Shimoda A; Araki L; Hatano K; Sakamoto Y; Kurihara T; Yamatodani A; Harusawa S
    J Org Chem; 2008 Mar; 73(6):2096-104. PubMed ID: 18278935
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Discovery of novel lead in the group of N-substituted piperazine ether derivatives with potential histamine H3 receptor activity.
    Kuder KJ; Stachnik M; Schunack W; Szymańska E; Kieć-Kononowicz K
    Med Chem; 2014; 10(6):588-99. PubMed ID: 24047214
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Clobenpropit analogs as dual activity ligands for the histamine H3 and H4 receptors: synthesis, pharmacological evaluation, and cross-target QSAR studies.
    Lim HD; Istyastono EP; van de Stolpe A; Romeo G; Gobbi S; Schepers M; Lahaye R; Menge WM; Zuiderveld OP; Jongejan A; Smits RA; Bakker RA; Haaksma EE; Leurs R; de Esch IJ
    Bioorg Med Chem; 2009 Jun; 17(11):3987-94. PubMed ID: 19414267
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Synthesis and biological activity of novel tert-butyl and tert-pentylphenoxyalkyl piperazine derivatives as histamine H
    Szczepańska K; Karcz T; Mogilski S; Siwek A; Kuder KJ; Latacz G; Kubacka M; Hagenow S; Lubelska A; Olejarz A; Kotańska M; Sadek B; Stark H; Kieć-Kononowicz K
    Eur J Med Chem; 2018 May; 152():223-234. PubMed ID: 29723785
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Non-imidazole histamine H3 receptor ligands incorporating antiepileptic moieties.
    Sadek B; Schwed JS; Subramanian D; Weizel L; Walter M; Adem A; Stark H
    Eur J Med Chem; 2014 Apr; 77():269-79. PubMed ID: 24650714
    [TBL] [Abstract][Full Text] [Related]  

  • 8. New lead elements for histamine H
    Espinosa-Bustos C; Frank A; Arancibia-Opazo S; Salas CO; Fierro A; Stark H
    Bioorg Med Chem Lett; 2018 Sep; 28(17):2890-2893. PubMed ID: 30025902
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Discovery of novel steroidal histamine H
    Ledneczki I; Tapolcsányi P; Gábor E; Éles J; Greiner I; Schmidt É; Némethy Z; Kedves RS; Balázs O; Román V; Lévay G; Mahó S
    Bioorg Med Chem Lett; 2017 Oct; 27(19):4525-4530. PubMed ID: 28888822
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Anticonvulsant effects of isomeric nonimidazole histamine H
    Sadek B; Saad A; Schwed JS; Weizel L; Walter M; Stark H
    Drug Des Devel Ther; 2016; 10():3633-3651. PubMed ID: 27853355
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Two novel and selective nonimidazole histamine H3 receptor antagonists A-304121 and A-317920: I. In vitro pharmacological effects.
    Esbenshade TA; Krueger KM; Miller TR; Kang CH; Denny LI; Witte DG; Yao BB; Fox GB; Faghih R; Bennani YL; Williams M; Hancock AA
    J Pharmacol Exp Ther; 2003 Jun; 305(3):887-96. PubMed ID: 12606603
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Autoregulation of McA-RH7777 hepatoma cell proliferation by histamine H3 receptors.
    Davenas E; Rouleau A; Morisset S; Arrang JM
    J Pharmacol Exp Ther; 2008 Aug; 326(2):406-13. PubMed ID: 18474684
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Histamine H
    Tanaka S; Sakaguchi M; Yoneyama H; Usami Y; Harusawa S
    Biochem Biophys Res Commun; 2016 Nov; 480(3):479-485. PubMed ID: 27773822
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Modeling G protein-coupled receptors for structure-based drug discovery using low-frequency normal modes for refinement of homology models: application to H3 antagonists.
    Rai BK; Tawa GJ; Katz AH; Humblet C
    Proteins; 2010 Feb; 78(2):457-73. PubMed ID: 19787776
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Compared pharmacology of human histamine H3 and H4 receptors: structure-activity relationships of histamine derivatives.
    Gbahou F; Vincent L; Humbert-Claude M; Tardivel-Lacombe J; Chabret C; Arrang JM
    Br J Pharmacol; 2006 Apr; 147(7):744-54. PubMed ID: 16432504
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Visualization of the activation of the histamine H3 receptor (H3R) using novel fluorescence resonance energy transfer biosensors and their potential application to the study of H3R pharmacology.
    Liu Y; Zeng H; Pediani JD; Ward RJ; Chen LY; Wu N; Ma L; Tang M; Yang Y; An S; Guo XX; Hao Q; Xu TR
    FEBS J; 2018 Jun; 285(12):2319-2336. PubMed ID: 29701013
    [TBL] [Abstract][Full Text] [Related]  

  • 17. The role of histamine in human mammary carcinogenesis: H3 and H4 receptors as potential therapeutic targets for breast cancer treatment.
    Medina V; Croci M; Crescenti E; Mohamad N; Sanchez-Jiménez F; Massari N; Nuñez M; Cricco G; Martin G; Bergoc R; Rivera E
    Cancer Biol Ther; 2008 Jan; 7(1):28-35. PubMed ID: 17932461
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Synthesis and preliminary pharmacological investigation of new N-substituted-N-[ω-(ω-phenoxy-alkylpiperazin-1-yl)alkyl]guanidines as non-imidazole histamine H(3) antagonists.
    Staszewski M; Walczyński K
    Arch Pharm (Weinheim); 2012 Jun; 345(6):431-43. PubMed ID: 22415744
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Discovery of aryl ureas and aryl amides as potent and selective histamine H3 receptor antagonists for the treatment of obesity (part I).
    Gao Z; Hurst WJ; Guillot E; Czechtizky W; Lukasczyk U; Nagorny R; Pruniaux MP; Schwink L; Sanchez JA; Stengelin S; Tang L; Winkler I; Hendrix JA; George PG
    Bioorg Med Chem Lett; 2013 Jun; 23(11):3416-20. PubMed ID: 23591110
    [TBL] [Abstract][Full Text] [Related]  

  • 20. 4-Hydroxypiperidines and Their Flexible 3-(Amino)propyloxy Analogues as Non-Imidazole Histamine H₃ Receptor Antagonist: Further Structure⁻Activity Relationship Exploration and In Vitro and In Vivo Pharmacological Evaluation.
    Olszewska B; Stasiak A; McNaught Flores D; Fogel WA; Leurs R; Walczyński K
    Int J Mol Sci; 2018 Apr; 19(4):. PubMed ID: 29671795
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 7.