BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

620 related articles for article (PubMed ID: 27593892)

  • 1. Giant Cellular Vacuoles Induced by Rare Earth Oxide Nanoparticles are Abnormally Enlarged Endo/Lysosomes and Promote mTOR-Dependent TFEB Nucleus Translocation.
    Lin J; Shi SS; Zhang JQ; Zhang YJ; Zhang L; Liu Y; Jin PP; Wei PF; Shi RH; Zhou W; Wen LP
    Small; 2016 Nov; 12(41):5759-5768. PubMed ID: 27593892
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Polystyrene Nanoparticles Reduced ROS and Inhibited Ferroptosis by Triggering Lysosome Stress and TFEB Nucleus Translocation in a Size-Dependent Manner.
    Li L; Sun S; Tan L; Wang Y; Wang L; Zhang Z; Zhang L
    Nano Lett; 2019 Nov; 19(11):7781-7792. PubMed ID: 31558022
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Glutamine-dependent lysosome homeostatic changes induced by starvation and lysosome inhibition.
    Wilden AR; Molina JA; Feuerborn M; Boyle D; Lee SY
    Biochim Biophys Acta Mol Cell Res; 2018 Sep; 1865(9):1356-1367. PubMed ID: 29966622
    [TBL] [Abstract][Full Text] [Related]  

  • 4. A lysosome-to-nucleus signalling mechanism senses and regulates the lysosome via mTOR and TFEB.
    Settembre C; Zoncu R; Medina DL; Vetrini F; Erdin S; Erdin S; Huynh T; Ferron M; Karsenty G; Vellard MC; Facchinetti V; Sabatini DM; Ballabio A
    EMBO J; 2012 Mar; 31(5):1095-108. PubMed ID: 22343943
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Multistep regulation of TFEB by MTORC1.
    Vega-Rubin-de-Celis S; Peña-Llopis S; Konda M; Brugarolas J
    Autophagy; 2017 Mar; 13(3):464-472. PubMed ID: 28055300
    [TBL] [Abstract][Full Text] [Related]  

  • 6. The transcription factor TFEB links mTORC1 signaling to transcriptional control of lysosome homeostasis.
    Roczniak-Ferguson A; Petit CS; Froehlich F; Qian S; Ky J; Angarola B; Walther TC; Ferguson SM
    Sci Signal; 2012 Jun; 5(228):ra42. PubMed ID: 22692423
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Curcumin targets the TFEB-lysosome pathway for induction of autophagy.
    Zhang J; Wang J; Xu J; Lu Y; Jiang J; Wang L; Shen HM; Xia D
    Oncotarget; 2016 Nov; 7(46):75659-75671. PubMed ID: 27689333
    [TBL] [Abstract][Full Text] [Related]  

  • 8. A novel curcumin analog binds to and activates TFEB in vitro and in vivo independent of MTOR inhibition.
    Song JX; Sun YR; Peluso I; Zeng Y; Yu X; Lu JH; Xu Z; Wang MZ; Liu LF; Huang YY; Chen LL; Durairajan SS; Zhang HJ; Zhou B; Zhang HQ; Lu A; Ballabio A; Medina DL; Guo Z; Li M
    Autophagy; 2016 Aug; 12(8):1372-89. PubMed ID: 27172265
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Enhanced translation expands the endo-lysosome size and promotes antigen presentation during phagocyte activation.
    Hipolito VEB; Diaz JA; Tandoc KV; Oertlin C; Ristau J; Chauhan N; Saric A; Mclaughlan S; Larsson O; Topisirovic I; Botelho RJ
    PLoS Biol; 2019 Dec; 17(12):e3000535. PubMed ID: 31800587
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Oblongifolin C suppresses lysosomal function independently of TFEB nuclear translocation.
    Wu M; Lao YZ; Tan HS; Lu G; Ren Y; Zheng ZQ; Yi J; Fu WW; Shen HM; Xu HX
    Acta Pharmacol Sin; 2019 Jul; 40(7):929-937. PubMed ID: 30333555
    [TBL] [Abstract][Full Text] [Related]  

  • 11. NOX2-Mediated TFEB Activation and Vacuolization Regulate Lysosome-Associated Cell Death Induced by Gypenoside L, a Saponin Isolated from Gynostemma pentaphyllum.
    Zheng K; Jiang Y; Liao C; Hu X; Li Y; Zeng Y; Zhang J; Wu X; Wu H; Liu L; Wang Y; He Z
    J Agric Food Chem; 2017 Aug; 65(31):6625-6637. PubMed ID: 28697598
    [TBL] [Abstract][Full Text] [Related]  

  • 12. TRIM37 deficiency induces autophagy through deregulating the MTORC1-TFEB axis.
    Wang W; Xia Z; Farré JC; Subramani S
    Autophagy; 2018; 14(9):1574-1585. PubMed ID: 29940807
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Impaired TFEB-mediated lysosomal biogenesis promotes the development of pancreatitis in mice and is associated with human pancreatitis.
    Wang S; Ni HM; Chao X; Wang H; Bridges B; Kumer S; Schmitt T; Mareninova O; Gukovskaya A; De Lisle RC; Ballabio A; Pacher P; Ding WX
    Autophagy; 2019 Nov; 15(11):1954-1969. PubMed ID: 30894069
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Time course decomposition of cell heterogeneity in TFEB signaling states reveals homeostatic mechanisms restricting the magnitude and duration of TFEB responses to mTOR activity modulation.
    Marin Zapata PA; Beese CJ; Jünger A; Dalmasso G; Brady NR; Hamacher-Brady A
    BMC Cancer; 2016 Jun; 16():355. PubMed ID: 27268034
    [TBL] [Abstract][Full Text] [Related]  

  • 15. TFEB at a glance.
    Napolitano G; Ballabio A
    J Cell Sci; 2016 Jul; 129(13):2475-81. PubMed ID: 27252382
    [TBL] [Abstract][Full Text] [Related]  

  • 16. SMURF1 controls the PPP3/calcineurin complex and TFEB at a regulatory node for lysosomal biogenesis.
    Xia Q; Zheng H; Li Y; Xu W; Wu C; Xu J; Li S; Zhang L; Dong L
    Autophagy; 2024 Apr; 20(4):735-751. PubMed ID: 37909662
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Up-regulation of lysosomal TRPML1 channels is essential for lysosomal adaptation to nutrient starvation.
    Wang W; Gao Q; Yang M; Zhang X; Yu L; Lawas M; Li X; Bryant-Genevier M; Southall NT; Marugan J; Ferrer M; Xu H
    Proc Natl Acad Sci U S A; 2015 Mar; 112(11):E1373-81. PubMed ID: 25733853
    [TBL] [Abstract][Full Text] [Related]  

  • 18. MPB, a novel berberine derivative, enhances lysosomal and bactericidal properties via TGF-β-activated kinase 1-dependent activation of the transcription factor EB.
    Liu X; Zhang N; Liu Y; Liu L; Zeng Q; Yin M; Wang Y; Song D; Deng H
    FASEB J; 2019 Jan; 33(1):1468-1481. PubMed ID: 30161000
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Importance of TFEB acetylation in control of its transcriptional activity and lysosomal function in response to histone deacetylase inhibitors.
    Zhang J; Wang J; Zhou Z; Park JE; Wang L; Wu S; Sun X; Lu L; Wang T; Lin Q; Sze SK; Huang D; Shen HM
    Autophagy; 2018; 14(6):1043-1059. PubMed ID: 30059277
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Sulforaphane Activates a lysosome-dependent transcriptional program to mitigate oxidative stress.
    Li D; Shao R; Wang N; Zhou N; Du K; Shi J; Wang Y; Zhao Z; Ye X; Zhang X; Xu H
    Autophagy; 2021 Apr; 17(4):872-887. PubMed ID: 32138578
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 31.