BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

391 related articles for article (PubMed ID: 27595346)

  • 1. Protecting genome integrity during CRISPR immune adaptation.
    Wright AV; Doudna JA
    Nat Struct Mol Biol; 2016 Oct; 23(10):876-883. PubMed ID: 27595346
    [TBL] [Abstract][Full Text] [Related]  

  • 2. How type II CRISPR-Cas establish immunity through Cas1-Cas2-mediated spacer integration.
    Xiao Y; Ng S; Nam KH; Ke A
    Nature; 2017 Oct; 550(7674):137-141. PubMed ID: 28869593
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Structures of the CRISPR genome integration complex.
    Wright AV; Liu JJ; Knott GJ; Doxzen KW; Nogales E; Doudna JA
    Science; 2017 Sep; 357(6356):1113-1118. PubMed ID: 28729350
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Asymmetric positioning of Cas1-2 complex and Integration Host Factor induced DNA bending guide the unidirectional homing of protospacer in CRISPR-Cas type I-E system.
    Yoganand KN; Sivathanu R; Nimkar S; Anand B
    Nucleic Acids Res; 2017 Jan; 45(1):367-381. PubMed ID: 27899566
    [TBL] [Abstract][Full Text] [Related]  

  • 5. CRISPR-Cas Systems Optimize Their Immune Response by Specifying the Site of Spacer Integration.
    McGinn J; Marraffini LA
    Mol Cell; 2016 Nov; 64(3):616-623. PubMed ID: 27618488
    [TBL] [Abstract][Full Text] [Related]  

  • 6. CRISPR Immunological Memory Requires a Host Factor for Specificity.
    Nuñez JK; Bai L; Harrington LB; Hinder TL; Doudna JA
    Mol Cell; 2016 Jun; 62(6):824-833. PubMed ID: 27211867
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Cas9 specifies functional viral targets during CRISPR-Cas adaptation.
    Heler R; Samai P; Modell JW; Weiner C; Goldberg GW; Bikard D; Marraffini LA
    Nature; 2015 Mar; 519(7542):199-202. PubMed ID: 25707807
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Integrase-mediated spacer acquisition during CRISPR-Cas adaptive immunity.
    Nuñez JK; Lee AS; Engelman A; Doudna JA
    Nature; 2015 Mar; 519(7542):193-8. PubMed ID: 25707795
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Molecular organization of the type II-A CRISPR adaptation module and its interaction with Cas9 via Csn2.
    Ka D; Jang DM; Han BW; Bae E
    Nucleic Acids Res; 2018 Oct; 46(18):9805-9815. PubMed ID: 30102386
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Cas4-Dependent Prespacer Processing Ensures High-Fidelity Programming of CRISPR Arrays.
    Lee H; Zhou Y; Taylor DW; Sashital DG
    Mol Cell; 2018 Apr; 70(1):48-59.e5. PubMed ID: 29602742
    [TBL] [Abstract][Full Text] [Related]  

  • 11. CRISPR Outsourcing: Commissioning IHF for Site-Specific Integration of Foreign DNA at the CRISPR Array.
    Wei Y; Terns MP
    Mol Cell; 2016 Jun; 62(6):803-804. PubMed ID: 27315553
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Cas1 and Cas2 From the Type II-C CRISPR-Cas System of
    He Y; Wang M; Liu M; Huang L; Liu C; Zhang X; Yi H; Cheng A; Zhu D; Yang Q; Wu Y; Zhao X; Chen S; Jia R; Zhang S; Liu Y; Yu Y; Zhang L
    Front Cell Infect Microbiol; 2018; 8():195. PubMed ID: 29951376
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Foreign DNA capture during CRISPR-Cas adaptive immunity.
    Nuñez JK; Harrington LB; Kranzusch PJ; Engelman AN; Doudna JA
    Nature; 2015 Nov; 527(7579):535-8. PubMed ID: 26503043
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Reconstitution of CRISPR adaptation in vitro and its detection by PCR.
    Fagerlund RD; Ferguson TJ; Maxwell HWR; Opel-Reading HK; Krause KL; Fineran PC
    Methods Enzymol; 2019; 616():411-433. PubMed ID: 30691653
    [TBL] [Abstract][Full Text] [Related]  

  • 15. CRISPR repeat sequences and relative spacing specify DNA integration by Pyrococcus furiosus Cas1 and Cas2.
    Grainy J; Garrett S; Graveley BR; P Terns M
    Nucleic Acids Res; 2019 Aug; 47(14):7518-7531. PubMed ID: 31219587
    [TBL] [Abstract][Full Text] [Related]  

  • 16. A CRISPR-Cas9-integrase complex generates precise DNA fragments for genome integration.
    Jakhanwal S; Cress BF; Maguin P; Lobba MJ; Marraffini LA; Doudna JA
    Nucleic Acids Res; 2021 Apr; 49(6):3546-3556. PubMed ID: 33693715
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Structure reveals why genome folding is necessary for site-specific integration of foreign DNA into CRISPR arrays.
    Santiago-Frangos A; Henriques WS; Wiegand T; Gauvin CC; Buyukyoruk M; Graham AB; Wilkinson RA; Triem L; Neselu K; Eng ET; Lander GC; Wiedenheft B
    Nat Struct Mol Biol; 2023 Nov; 30(11):1675-1685. PubMed ID: 37710013
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Foreign DNA acquisition by the I-F CRISPR-Cas system requires all components of the interference machinery.
    Vorontsova D; Datsenko KA; Medvedeva S; Bondy-Denomy J; Savitskaya EE; Pougach K; Logacheva M; Wiedenheft B; Davidson AR; Severinov K; Semenova E
    Nucleic Acids Res; 2015 Dec; 43(22):10848-60. PubMed ID: 26586803
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Structural plasticity and in vivo activity of Cas1 from the type I-F CRISPR-Cas system.
    Wilkinson ME; Nakatani Y; Staals RH; Kieper SN; Opel-Reading HK; McKenzie RE; Fineran PC; Krause KL
    Biochem J; 2016 Apr; 473(8):1063-72. PubMed ID: 26929403
    [TBL] [Abstract][Full Text] [Related]  

  • 20. CRISPR type II-A subgroups exhibit phylogenetically distinct mechanisms for prespacer insertion.
    Van Orden MJ; Newsom S; Rajan R
    J Biol Chem; 2020 Aug; 295(32):10956-10968. PubMed ID: 32513871
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 20.