BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

186 related articles for article (PubMed ID: 27597417)

  • 1. Stabilization of c-myc G-Quadruplex DNA, inhibition of telomerase activity, disruption of mitochondrial functions and tumor cell apoptosis by platinum(II) complex with 9-amino-oxoisoaporphine.
    Qin JL; Qin QP; Wei ZZ; Yu YC; Meng T; Wu CX; Liang YL; Liang H; Chen ZF
    Eur J Med Chem; 2016 Nov; 124():417-427. PubMed ID: 27597417
    [TBL] [Abstract][Full Text] [Related]  

  • 2. High in vivo antitumor activity of cobalt oxoisoaporphine complexes by targeting G-quadruplex DNA, telomerase and disrupting mitochondrial functions.
    Qin QP; Qin JL; Meng T; Lin WH; Zhang CH; Wei ZZ; Chen JN; Liu YC; Liang H; Chen ZF
    Eur J Med Chem; 2016 Nov; 124():380-392. PubMed ID: 27597414
    [TBL] [Abstract][Full Text] [Related]  

  • 3. 5-Bromo-oxoisoaporphine platinum(II) complexes exhibit tumor cell cytotoxcicity via inhibition of telomerase activity and disruption of c-myc G-quadruplex DNA and mitochondrial functions.
    Wei ZZ; Qin QP; Meng T; Deng CX; Liang H; Chen ZF
    Eur J Med Chem; 2018 Feb; 145():360-369. PubMed ID: 29335202
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Preparation of 4-([2,2':6',2″-terpyridin]-4'-yl)-N,N-diethylaniline Ni(II) and Pt(II) complexes and exploration of their in vitro cytotoxic activities.
    Zou HH; Wang L; Long ZX; Qin QP; Song ZK; Xie T; Zhang SH; Liu YC; Lin B; Chen ZF
    Eur J Med Chem; 2016 Jan; 108():1-12. PubMed ID: 26619388
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Stabilization of G-quadruplex DNA, inhibition of telomerase activity, and tumor cell apoptosis by organoplatinum(II) complexes with oxoisoaporphine.
    Chen ZF; Qin QP; Qin JL; Liu YC; Huang KB; Li YL; Meng T; Zhang GH; Peng Y; Luo XJ; Liang H
    J Med Chem; 2015 Mar; 58(5):2159-79. PubMed ID: 25650792
    [TBL] [Abstract][Full Text] [Related]  

  • 6. A platinum(II) complex of liriodenine from traditional Chinese medicine (TCM): Cell cycle arrest, cell apoptosis induction and telomerase inhibition activity via G-quadruplex DNA stabilization.
    Li YL; Qin QP; Liu YC; Chen ZF; Liang H
    J Inorg Biochem; 2014 Aug; 137():12-21. PubMed ID: 24798373
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Novel tacrine platinum(II) complexes display high anticancer activity via inhibition of telomerase activity, dysfunction of mitochondria, and activation of the p53 signaling pathway.
    Qin QP; Wang SL; Tan MX; Wang ZF; Luo DM; Zou BQ; Liu YC; Yao PF; Liang H
    Eur J Med Chem; 2018 Oct; 158():106-122. PubMed ID: 30205260
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Structure and biological properties of five Pt(II) complexes as potential anticancer agents.
    Deng J; Wang J; Khan M; Yu P; Yang F; Liang H
    J Inorg Biochem; 2018 Aug; 185():10-16. PubMed ID: 29730232
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Oxoaporphine Metal Complexes (Co
    Qin JL; Shen WY; Chen ZF; Zhao LF; Qin QP; Yu YC; Liang H
    Sci Rep; 2017 Apr; 7():46056. PubMed ID: 28436418
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Water-Soluble Ruthenium(II) Complexes with Chiral 4-(2,3-Dihydroxypropyl)-formamide Oxoaporphine (FOA): In Vitro and in Vivo Anticancer Activity by Stabilization of G-Quadruplex DNA, Inhibition of Telomerase Activity, and Induction of Tumor Cell Apoptosis.
    Chen ZF; Qin QP; Qin JL; Zhou J; Li YL; Li N; Liu YC; Liang H
    J Med Chem; 2015 Jun; 58(11):4771-89. PubMed ID: 25988535
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Enhanced G-Quadruplex DNA Stabilization and Telomerase Inhibition by Novel Fluorescein Derived Salen and Salphen Based Ni(II) and Pd(II) Complexes.
    Ali A; Kamra M; Roy S; Muniyappa K; Bhattacharya S
    Bioconjug Chem; 2017 Feb; 28(2):341-352. PubMed ID: 28165710
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Novel platinum complexes as efficient G-quadruplex DNA binders and telomerase inhibitors.
    Wei C; Wen Y; Wang J
    Int J Biol Macromol; 2013 Apr; 55():185-92. PubMed ID: 23313450
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Design, Synthesis, and Evaluation of Isaindigotone Derivatives To Downregulate c-myc Transcription via Disrupting the Interaction of NM23-H2 with G-Quadruplex.
    Shan C; Yan JW; Wang YQ; Che T; Huang ZL; Chen AC; Yao PF; Tan JH; Li D; Ou TM; Gu LQ; Huang ZS
    J Med Chem; 2017 Feb; 60(4):1292-1308. PubMed ID: 28128954
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Ruthenium(II) complexes as apoptosis inducers by stabilizing c-myc G-quadruplex DNA.
    Zhang Z; Wu Q; Wu XH; Sun FY; Chen LM; Chen JC; Yang SL; Mei WJ
    Eur J Med Chem; 2014 Jun; 80():316-24. PubMed ID: 24793882
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Stabilization of G-quadruplex DNA with platinum(II) Schiff base complexes: luminescent probe and down-regulation of c-myc oncogene expression.
    Wu P; Ma DL; Leung CH; Yan SC; Zhu N; Abagyan R; Che CM
    Chemistry; 2009 Dec; 15(47):13008-21. PubMed ID: 19876976
    [TBL] [Abstract][Full Text] [Related]  

  • 16. The induction of apoptosis in HepG-2 cells by ruthenium(II) complexes through an intrinsic ROS-mediated mitochondrial dysfunction pathway.
    Zeng CC; Lai SH; Yao JH; Zhang C; Yin H; Li W; Han BJ; Liu YJ
    Eur J Med Chem; 2016 Oct; 122():118-126. PubMed ID: 27344489
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Insights into anticancer activity and mechanism of action of a ruthenium(II) complex in human esophageal squamous carcinoma EC109 cells.
    Guo L; Lv G; Qiu L; Yang H; Zhang L; Yu H; Zou M; Lin J
    Eur J Pharmacol; 2016 Sep; 786():60-71. PubMed ID: 27262377
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Preparation of 6/8/11-Amino/Chloro-Oxoisoaporphine and Group-10 Metal Complexes and Evaluation of Their in Vitro and in Vivo Antitumor Activity.
    Qin QP; Qin JL; Meng T; Yang GA; Wei ZZ; Liu YC; Liang H; Chen ZF
    Sci Rep; 2016 Nov; 6():37644. PubMed ID: 27898051
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Synthesis and antitumor mechanisms of two novel platinum(ii) complexes with 3-(2'-benzimidazolyl)-7-methoxycoumarin.
    Qin QP; Wang SL; Tan MX; Wang ZF; Huang XL; Wei QM; Shi BB; Zou BQ; Liang H
    Metallomics; 2018 Aug; 10(8):1160-1169. PubMed ID: 30083683
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Synthesis, crystal structure and biological evaluation of a new dasatinib copper(II) complex as telomerase inhibitor.
    Qin QP; Meng T; Tan MX; Liu YC; Luo XJ; Zou BQ; Liang H
    Eur J Med Chem; 2018 Jan; 143():1597-1603. PubMed ID: 29133054
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.