These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

469 related articles for article (PubMed ID: 27598417)

  • 1. In Vitro Investigation of Crosstalk between Fatty Acid and Polyketide Synthases in the Andrimid Biosynthetic Assembly Line.
    Ishikawa F; Sugimoto H; Kakeya H
    Chembiochem; 2016 Nov; 17(22):2137-2142. PubMed ID: 27598417
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Self-malonylation is an intrinsic property of a chemically synthesized type II polyketide synthase acyl carrier protein.
    Arthur CJ; Szafranska A; Evans SE; Findlow SC; Burston SG; Owen P; Clark-Lewis I; Simpson TJ; Crosby J; Crump MP
    Biochemistry; 2005 Nov; 44(46):15414-21. PubMed ID: 16285746
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Polyketide synthase acyl carrier protein (ACP) as a substrate and a catalyst for malonyl ACP biosynthesis.
    Zhou P; Florova G; Reynolds KA
    Chem Biol; 1999 Aug; 6(8):577-84. PubMed ID: 10421763
    [TBL] [Abstract][Full Text] [Related]  

  • 4. MCAT is not required for in vitro polyketide synthesis in a minimal actinorhodin polyketide synthase from Streptomyces coelicolor.
    Matharu AL; Cox RJ; Crosby J; Byrom KJ; Simpson TJ
    Chem Biol; 1998 Dec; 5(12):699-711. PubMed ID: 9862793
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Kinetic and mechanistic analysis of the malonyl CoA:ACP transacylase from Streptomyces coelicolor indicates a single catalytically competent serine nucleophile at the active site.
    Szafranska AE; Hitchman TS; Cox RJ; Crosby J; Simpson TJ
    Biochemistry; 2002 Feb; 41(5):1421-7. PubMed ID: 11814333
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Structure and malonyl CoA-ACP transacylase binding of streptomyces coelicolor fatty acid synthase acyl carrier protein.
    Arthur CJ; Williams C; Pottage K; Płoskoń E; Findlow SC; Burston SG; Simpson TJ; Crump MP; Crosby J
    ACS Chem Biol; 2009 Aug; 4(8):625-36. PubMed ID: 19555075
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Catalytic self-acylation of type II polyketide synthase acyl carrier proteins.
    Hitchman TS; Crosby J; Byrom KJ; Cox RJ; Simpson TJ
    Chem Biol; 1998 Jan; 5(1):35-47. PubMed ID: 9479478
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Reconstitution of the FK228 biosynthetic pathway reveals cross talk between modular polyketide synthases and fatty acid synthase.
    Wesener SR; Potharla VY; Cheng YQ
    Appl Environ Microbiol; 2011 Feb; 77(4):1501-7. PubMed ID: 21183648
    [TBL] [Abstract][Full Text] [Related]  

  • 9. The malonyl transferase activity of type II polyketide synthase acyl carrier proteins.
    Arthur CJ; Szafranska AE; Long J; Mills J; Cox RJ; Findlow SC; Simpson TJ; Crump MP; Crosby J
    Chem Biol; 2006 Jun; 13(6):587-96. PubMed ID: 16793516
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Malonyl-coenzyme A:acyl carrier protein acyltransferase of Streptomyces glaucescens: a possible link between fatty acid and polyketide biosynthesis.
    Summers RG; Ali A; Shen B; Wessel WA; Hutchinson CR
    Biochemistry; 1995 Jul; 34(29):9389-402. PubMed ID: 7626609
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Ketosynthases in the initiation and elongation modules of aromatic polyketide synthases have orthogonal acyl carrier protein specificity.
    Tang Y; Lee TS; Kobayashi S; Khosla C
    Biochemistry; 2003 Jun; 42(21):6588-95. PubMed ID: 12767243
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Enzymes involved in fatty acid and polyketide biosynthesis in Streptomyces glaucescens: role of FabH and FabD and their acyl carrier protein specificity.
    Florova G; Kazanina G; Reynolds KA
    Biochemistry; 2002 Aug; 41(33):10462-71. PubMed ID: 12173933
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Biochemical characterization of acyl carrier protein (AcpM) and malonyl-CoA:AcpM transacylase (mtFabD), two major components of Mycobacterium tuberculosis fatty acid synthase II.
    Kremer L; Nampoothiri KM; Lesjean S; Dover LG; Graham S; Betts J; Brennan PJ; Minnikin DE; Locht C; Besra GS
    J Biol Chem; 2001 Jul; 276(30):27967-74. PubMed ID: 11373295
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Catalytic relationships between type I and type II iterative polyketide synthases: The Aspergillus parasiticus norsolorinic acid synthase.
    Ma Y; Smith LH; Cox RJ; Beltran-Alvarez P; Arthur CJ; Simpson F R S TJ
    Chembiochem; 2006 Dec; 7(12):1951-8. PubMed ID: 17086560
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Comparative analysis of the substrate specificity of trans- versus cis-acyltransferases of assembly line polyketide synthases.
    Dunn BJ; Watts KR; Robbins T; Cane DE; Khosla C
    Biochemistry; 2014 Jun; 53(23):3796-806. PubMed ID: 24871074
    [TBL] [Abstract][Full Text] [Related]  

  • 16. The AT₂ domain of KirCI loads malonyl extender units to the ACPs of the kirromycin PKS.
    Musiol EM; Greule A; Härtner T; Kulik A; Wohlleben W; Weber T
    Chembiochem; 2013 Jul; 14(11):1343-52. PubMed ID: 23828654
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Demonstration of starter unit interprotein transfer from a fatty acid synthase to a multidomain, nonreducing polyketide synthase.
    Foulke-Abel J; Townsend CA
    Chembiochem; 2012 Sep; 13(13):1880-4. PubMed ID: 22807303
    [TBL] [Abstract][Full Text] [Related]  

  • 18. A transglutaminase homologue as a condensation catalyst in antibiotic assembly lines.
    Fortin PD; Walsh CT; Magarvey NA
    Nature; 2007 Aug; 448(7155):824-7. PubMed ID: 17653193
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Mechanistic analysis of a type II polyketide synthase. Role of conserved residues in the beta-ketoacyl synthase-chain length factor heterodimer.
    Dreier J; Khosla C
    Biochemistry; 2000 Feb; 39(8):2088-95. PubMed ID: 10684659
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Myxovirescin A biosynthesis is directed by hybrid polyketide synthases/nonribosomal peptide synthetase, 3-hydroxy-3-methylglutaryl-CoA synthases, and trans-acting acyltransferases.
    Simunovic V; Zapp J; Rachid S; Krug D; Meiser P; Müller R
    Chembiochem; 2006 Aug; 7(8):1206-20. PubMed ID: 16835859
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 24.