174 related articles for article (PubMed ID: 27601226)
1. Sost, independent of the non-coding enhancer ECR5, is required for bone mechanoadaptation.
Robling AG; Kang KS; Bullock WA; Foster WH; Murugesh D; Loots GG; Genetos DC
Bone; 2016 Nov; 92():180-188. PubMed ID: 27601226
[TBL] [Abstract][Full Text] [Related]
2. Targeted deletion of Sost distal enhancer increases bone formation and bone mass.
Collette NM; Genetos DC; Economides AN; Xie L; Shahnazari M; Yao W; Lane NE; Harland RM; Loots GG
Proc Natl Acad Sci U S A; 2012 Aug; 109(35):14092-7. PubMed ID: 22886088
[TBL] [Abstract][Full Text] [Related]
3. Sost downregulation and local Wnt signaling are required for the osteogenic response to mechanical loading.
Tu X; Rhee Y; Condon KW; Bivi N; Allen MR; Dwyer D; Stolina M; Turner CH; Robling AG; Plotkin LI; Bellido T
Bone; 2012 Jan; 50(1):209-17. PubMed ID: 22075208
[TBL] [Abstract][Full Text] [Related]
4. Analysis of SOST expression using large minigenes reveals the MEF2C binding site in the evolutionarily conserved region (ECR5) enhancer mediates forskolin, but not 1,25-dihydroxyvitamin D
St John HC; Hansen SJ; Pike JW
J Steroid Biochem Mol Biol; 2016 Nov; 164():277-280. PubMed ID: 26361013
[TBL] [Abstract][Full Text] [Related]
5. The Wnt Inhibitor Sclerostin Is Up-regulated by Mechanical Unloading in Osteocytes in Vitro.
Spatz JM; Wein MN; Gooi JH; Qu Y; Garr JL; Liu S; Barry KJ; Uda Y; Lai F; Dedic C; Balcells-Camps M; Kronenberg HM; Babij P; Pajevic PD
J Biol Chem; 2015 Jul; 290(27):16744-58. PubMed ID: 25953900
[TBL] [Abstract][Full Text] [Related]
6. Sclerostin mediates bone response to mechanical unloading through antagonizing Wnt/beta-catenin signaling.
Lin C; Jiang X; Dai Z; Guo X; Weng T; Wang J; Li Y; Feng G; Gao X; He L
J Bone Miner Res; 2009 Oct; 24(10):1651-61. PubMed ID: 19419300
[TBL] [Abstract][Full Text] [Related]
7. Mechanical stimulation of bone in vivo reduces osteocyte expression of Sost/sclerostin.
Robling AG; Niziolek PJ; Baldridge LA; Condon KW; Allen MR; Alam I; Mantila SM; Gluhak-Heinrich J; Bellido TM; Harris SE; Turner CH
J Biol Chem; 2008 Feb; 283(9):5866-75. PubMed ID: 18089564
[TBL] [Abstract][Full Text] [Related]
8. TGF-β regulates sclerostin expression via the ECR5 enhancer.
Loots GG; Keller H; Leupin O; Murugesh D; Collette NM; Genetos DC
Bone; 2012 Mar; 50(3):663-9. PubMed ID: 22155511
[TBL] [Abstract][Full Text] [Related]
9. Targeted deletion of the sclerostin gene in mice results in increased bone formation and bone strength.
Li X; Ominsky MS; Niu QT; Sun N; Daugherty B; D'Agostin D; Kurahara C; Gao Y; Cao J; Gong J; Asuncion F; Barrero M; Warmington K; Dwyer D; Stolina M; Morony S; Sarosi I; Kostenuik PJ; Lacey DL; Simonet WS; Ke HZ; Paszty C
J Bone Miner Res; 2008 Jun; 23(6):860-9. PubMed ID: 18269310
[TBL] [Abstract][Full Text] [Related]
10. Control of the SOST bone enhancer by PTH using MEF2 transcription factors.
Leupin O; Kramer I; Collette NM; Loots GG; Natt F; Kneissel M; Keller H
J Bone Miner Res; 2007 Dec; 22(12):1957-67. PubMed ID: 17696759
[TBL] [Abstract][Full Text] [Related]
11. Sclerostin neutralization unleashes the osteoanabolic effects of Dkk1 inhibition.
Witcher PC; Miner SE; Horan DJ; Bullock WA; Lim KE; Kang KS; Adaniya AL; Ross RD; Loots GG; Robling AG
JCI Insight; 2018 Jun; 3(11):. PubMed ID: 29875318
[TBL] [Abstract][Full Text] [Related]
12. 1α,25-dihydroxyvitamin D3 stimulates human SOST gene expression and sclerostin secretion.
Wijenayaka AR; Yang D; Prideaux M; Ito N; Kogawa M; Anderson PH; Morris HA; Solomon LB; Loots GG; Findlay DM; Atkins GJ
Mol Cell Endocrinol; 2015 Sep; 413():157-67. PubMed ID: 26112182
[TBL] [Abstract][Full Text] [Related]
13. Mechanical load increases in bone formation via a sclerostin-independent pathway.
Morse A; McDonald MM; Kelly NH; Melville KM; Schindeler A; Kramer I; Kneissel M; van der Meulen MC; Little DG
J Bone Miner Res; 2014 Nov; 29(11):2456-67. PubMed ID: 24821585
[TBL] [Abstract][Full Text] [Related]
14. Paradoxical response to mechanical unloading in bone loss, microarchitecture, and bone turnover markers.
Sun X; Yang K; Wang C; Cao S; Merritt M; Hu Y; Xu X
Int J Med Sci; 2015; 12(3):270-9. PubMed ID: 25798053
[TBL] [Abstract][Full Text] [Related]
15. Sclerostin expression is induced by BMPs in human Saos-2 osteosarcoma cells but not via direct effects on the sclerostin gene promoter or ECR5 element.
Yu L; van der Valk M; Cao J; Han CY; Juan T; Bass MB; Deshpande C; Damore MA; Stanton R; Babij P
Bone; 2011 Dec; 49(6):1131-40. PubMed ID: 21890009
[TBL] [Abstract][Full Text] [Related]
16. Loss of mechanosensitive sclerostin may accelerate cranial bone growth and regeneration.
Kang KS; Lastfogel J; Ackerman LL; Jea A; Robling AG; Tholpady SS
J Neurosurg; 2018 Oct; 129(4):1085-1091. PubMed ID: 29125417
[TBL] [Abstract][Full Text] [Related]
17. Bone marrow mechanotransduction in porcine explants alters kinase activation and enhances trabecular bone formation in the absence of osteocyte signaling.
Curtis KJ; Coughlin TR; Mason DE; Boerckel JD; Niebur GL
Bone; 2018 Feb; 107():78-87. PubMed ID: 29154967
[TBL] [Abstract][Full Text] [Related]
18. Activation of Wnt Signaling by Mechanical Loading Is Impaired in the Bone of Old Mice.
Holguin N; Brodt MD; Silva MJ
J Bone Miner Res; 2016 Dec; 31(12):2215-2226. PubMed ID: 27357062
[TBL] [Abstract][Full Text] [Related]
19. Osteocytes and WNT: the mechanical control of bone formation.
Galli C; Passeri G; Macaluso GM
J Dent Res; 2010 Apr; 89(4):331-43. PubMed ID: 20200416
[TBL] [Abstract][Full Text] [Related]
20. HDAC5 controls MEF2C-driven sclerostin expression in osteocytes.
Wein MN; Spatz J; Nishimori S; Doench J; Root D; Babij P; Nagano K; Baron R; Brooks D; Bouxsein M; Pajevic PD; Kronenberg HM
J Bone Miner Res; 2015 Mar; 30(3):400-11. PubMed ID: 25271055
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
