160 related articles for article (PubMed ID: 27602694)
1. In Silico Prediction of Volume of Distribution in Humans. Extensive Data Set and the Exploration of Linear and Nonlinear Methods Coupled with Molecular Interaction Fields Descriptors.
Lombardo F; Jing Y
J Chem Inf Model; 2016 Oct; 56(10):2042-2052. PubMed ID: 27602694
[TBL] [Abstract][Full Text] [Related]
2. An Accurate In Vitro Prediction of Human VD
Berellini G; Lombardo F
Drug Metab Dispos; 2019 Dec; 47(12):1380-1387. PubMed ID: 31578209
[TBL] [Abstract][Full Text] [Related]
3. In silico prediction of volume of distribution in human using linear and nonlinear models on a 669 compound data set.
Berellini G; Springer C; Waters NJ; Lombardo F
J Med Chem; 2009 Jul; 52(14):4488-95. PubMed ID: 19603833
[TBL] [Abstract][Full Text] [Related]
4. In Silico Models of Human PK Parameters. Prediction of Volume of Distribution Using an Extensive Data Set and a Reduced Number of Parameters.
Lombardo F; Bentzien J; Berellini G; Muegge I
J Pharm Sci; 2021 Jan; 110(1):500-509. PubMed ID: 32891631
[TBL] [Abstract][Full Text] [Related]
5. Quantitative structure-activity relationship models of clinical pharmacokinetics: clearance and volume of distribution.
Gombar VK; Hall SD
J Chem Inf Model; 2013 Apr; 53(4):948-57. PubMed ID: 23451981
[TBL] [Abstract][Full Text] [Related]
6. A hybrid mixture discriminant analysis-random forest computational model for the prediction of volume of distribution of drugs in human.
Lombardo F; Obach RS; Dicapua FM; Bakken GA; Lu J; Potter DM; Gao F; Miller MD; Zhang Y
J Med Chem; 2006 Apr; 49(7):2262-7. PubMed ID: 16570922
[TBL] [Abstract][Full Text] [Related]
7. Analysing molecular polar surface descriptors to predict blood-brain barrier permeation.
Shityakov S; Neuhaus W; Dandekar T; Förster C
Int J Comput Biol Drug Des; 2013; 6(1-2):146-56. PubMed ID: 23428480
[TBL] [Abstract][Full Text] [Related]
8. A comprehensive support vector machine binary hERG classification model based on extensive but biased end point hERG data sets.
Shen MY; Su BH; Esposito EX; Hopfinger AJ; Tseng YJ
Chem Res Toxicol; 2011 Jun; 24(6):934-49. PubMed ID: 21504223
[TBL] [Abstract][Full Text] [Related]
9. PhRMA CPCDC initiative on predictive models of human pharmacokinetics, part 4: prediction of plasma concentration-time profiles in human from in vivo preclinical data by using the Wajima approach.
Vuppugalla R; Marathe P; He H; Jones RD; Yates JW; Jones HM; Gibson CR; Chien JY; Ring BJ; Adkison KK; Ku MS; Fischer V; Dutta S; Sinha VK; Björnsson T; Lavé T; Poulin P
J Pharm Sci; 2011 Oct; 100(10):4111-26. PubMed ID: 21480234
[TBL] [Abstract][Full Text] [Related]
10. PhRMA CPCDC initiative on predictive models of human pharmacokinetics, part 2: comparative assessment of prediction methods of human volume of distribution.
Jones RD; Jones HM; Rowland M; Gibson CR; Yates JW; Chien JY; Ring BJ; Adkison KK; Ku MS; He H; Vuppugalla R; Marathe P; Fischer V; Dutta S; Sinha VK; Björnsson T; Lavé T; Poulin P
J Pharm Sci; 2011 Oct; 100(10):4074-89. PubMed ID: 21452299
[TBL] [Abstract][Full Text] [Related]
11. Prediction of human pharmacokinetics from animal data and molecular structural parameters using multivariate regression analysis: volume of distribution at steady state.
Wajima T; Fukumura K; Yano Y; Oguma T
J Pharm Pharmacol; 2003 Jul; 55(7):939-49. PubMed ID: 12906751
[TBL] [Abstract][Full Text] [Related]
12. Prediction of human pharmacokinetics from animal data and molecular structural parameters using multivariate regression analysis: oral clearance.
Wajima T; Fukumura K; Yano Y; Oguma T
J Pharm Sci; 2003 Dec; 92(12):2427-40. PubMed ID: 14603488
[TBL] [Abstract][Full Text] [Related]
13. In silico prediction of total human plasma clearance.
Berellini G; Waters NJ; Lombardo F
J Chem Inf Model; 2012 Aug; 52(8):2069-78. PubMed ID: 22715914
[TBL] [Abstract][Full Text] [Related]
14. Contribution of molecular properties to extrapolation of the volume of distribution in human from preclinical animal species data.
Sui X; Sun J; Li H; Pan Y; Wang Y; He Z
Biopharm Drug Dispos; 2010 Nov; 31(8-9):464-75. PubMed ID: 20878878
[TBL] [Abstract][Full Text] [Related]
15. In Silico Prediction of Human Intravenous Pharmacokinetic Parameters with Improved Accuracy.
Wang Y; Liu H; Fan Y; Chen X; Yang Y; Zhu L; Zhao J; Chen Y; Zhang Y
J Chem Inf Model; 2019 Sep; 59(9):3968-3980. PubMed ID: 31403793
[TBL] [Abstract][Full Text] [Related]
16. Predicting Volume of Distribution in Humans: Performance of In Silico Methods for a Large Set of Structurally Diverse Clinical Compounds.
Murad N; Pasikanti KK; Madej BD; Minnich A; McComas JM; Crouch S; Polli JW; Weber AD
Drug Metab Dispos; 2021 Feb; 49(2):169-178. PubMed ID: 33239335
[TBL] [Abstract][Full Text] [Related]
17. In silico human and rat Vss quantitative structure-activity relationship models.
Gleeson MP; Waters NJ; Paine SW; Davis AM
J Med Chem; 2006 Mar; 49(6):1953-63. PubMed ID: 16539383
[TBL] [Abstract][Full Text] [Related]
18. PhRMA CPCDC initiative on predictive models of human pharmacokinetics, part 3: comparative assessement of prediction methods of human clearance.
Ring BJ; Chien JY; Adkison KK; Jones HM; Rowland M; Jones RD; Yates JW; Ku MS; Gibson CR; He H; Vuppugalla R; Marathe P; Fischer V; Dutta S; Sinha VK; Björnsson T; Lavé T; Poulin P
J Pharm Sci; 2011 Oct; 100(10):4090-110. PubMed ID: 21541938
[TBL] [Abstract][Full Text] [Related]
19. Prediction of human volume of distribution values for drugs using linear and nonlinear quantitative structure pharmacokinetic relationship models.
Louis B; Agrawal VK
Interdiscip Sci; 2014 Mar; 6(1):71-83. PubMed ID: 24464707
[TBL] [Abstract][Full Text] [Related]
20.
; ; . PubMed ID:
[No Abstract] [Full Text] [Related]
[Next] [New Search]
