These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

160 related articles for article (PubMed ID: 27602694)

  • 21. Quantitative Structure - Pharmacokinetics Relationships Analysis of Basic Drugs: Volume of Distribution.
    Zhivkova ZD; Mandova T; Doytchinova I
    J Pharm Pharm Sci; 2015; 18(3):515-27. PubMed ID: 26517139
    [TBL] [Abstract][Full Text] [Related]  

  • 22. ADME evaluation in drug discovery. 3. Modeling blood-brain barrier partitioning using simple molecular descriptors.
    Hou TJ; Xu XJ
    J Chem Inf Comput Sci; 2003; 43(6):2137-52. PubMed ID: 14632466
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Using open source computational tools for predicting human metabolic stability and additional absorption, distribution, metabolism, excretion, and toxicity properties.
    Gupta RR; Gifford EM; Liston T; Waller CL; Hohman M; Bunin BA; Ekins S
    Drug Metab Dispos; 2010 Nov; 38(11):2083-90. PubMed ID: 20693417
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Computational models to assign biopharmaceutics drug disposition classification from molecular structure.
    Khandelwal A; Bahadduri PM; Chang C; Polli JE; Swaan PW; Ekins S
    Pharm Res; 2007 Dec; 24(12):2249-62. PubMed ID: 17846869
    [TBL] [Abstract][Full Text] [Related]  

  • 25. ADME evaluation in drug discovery. 1. Applications of genetic algorithms to the prediction of blood-brain partitioning of a large set of drugs.
    Hou T; Xu X
    J Mol Model; 2002 Dec; 8(12):337-49. PubMed ID: 12541001
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Prediction of the brain-blood distribution of a large set of drugs from structurally derived descriptors using partial least-squares (PLS) modeling.
    Luco JM
    J Chem Inf Comput Sci; 1999; 39(2):396-404. PubMed ID: 10192950
    [TBL] [Abstract][Full Text] [Related]  

  • 27. Development of in Silico Models for Predicting P-Glycoprotein Inhibitors Based on a Two-Step Approach for Feature Selection and Its Application to Chinese Herbal Medicine Screening.
    Yang M; Chen J; Shi X; Xu L; Xi Z; You L; An R; Wang X
    Mol Pharm; 2015 Oct; 12(10):3691-713. PubMed ID: 26376206
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Critically Assessing the Predictive Power of QSAR Models for Human Liver Microsomal Stability.
    Liu R; Schyman P; Wallqvist A
    J Chem Inf Model; 2015 Aug; 55(8):1566-75. PubMed ID: 26170251
    [TBL] [Abstract][Full Text] [Related]  

  • 29. High-throughput in-silico prediction of ionization equilibria for pharmacokinetic modeling.
    Strope CL; Mansouri K; Clewell HJ; Rabinowitz JR; Stevens C; Wambaugh JF
    Sci Total Environ; 2018 Feb; 615():150-160. PubMed ID: 28964990
    [TBL] [Abstract][Full Text] [Related]  

  • 30. Modeling and Prediction of Solvent Effect on Human Skin Permeability using Support Vector Regression and Random Forest.
    Baba H; Takahara J; Yamashita F; Hashida M
    Pharm Res; 2015 Nov; 32(11):3604-17. PubMed ID: 26033768
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Applying linear and non-linear methods for parallel prediction of volume of distribution and fraction of unbound drug.
    del Amo EM; Ghemtio L; Xhaard H; Yliperttula M; Urtti A; Kidron H
    PLoS One; 2013; 8(10):e74758. PubMed ID: 24116008
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Prediction of steady-state volume of distribution of acidic drugs by quantitative structure-pharmacokinetics relationships.
    Zhivkova Z; Doytchinova I
    J Pharm Sci; 2012 Mar; 101(3):1253-66. PubMed ID: 22170307
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Validation of Early Human Dose Prediction: A Key Metric for Compound Progression in Drug Discovery.
    Page KM
    Mol Pharm; 2016 Feb; 13(2):609-20. PubMed ID: 26696327
    [TBL] [Abstract][Full Text] [Related]  

  • 34. In silico binary classification QSAR models based on 4D-fingerprints and MOE descriptors for prediction of hERG blockage.
    Su BH; Shen MY; Esposito EX; Hopfinger AJ; Tseng YJ
    J Chem Inf Model; 2010 Jul; 50(7):1304-18. PubMed ID: 20565102
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Prediction of human clearance based on animal data and molecular properties.
    Huang W; Geng L; Deng R; Lu S; Ma G; Yu J; Zhang J; Liu W; Hou T; Lu X
    Chem Biol Drug Des; 2015 Nov; 86(5):990-7. PubMed ID: 25845625
    [TBL] [Abstract][Full Text] [Related]  

  • 36. Prediction of polar surface area of drug molecules: a QSPR approach.
    Noorizadeh H; Farmany A; Noorizadeh M; Kohzadi M
    Drug Test Anal; 2013 Apr; 5(4):222-7. PubMed ID: 21539000
    [TBL] [Abstract][Full Text] [Related]  

  • 37. A quantitative structure-activity relationship (QSAR) study of dermal absorption using theoretical molecular descriptors.
    Basak SC; Mills D; Mumtaz MM
    SAR QSAR Environ Res; 2007; 18(1-2):45-55. PubMed ID: 17365958
    [TBL] [Abstract][Full Text] [Related]  

  • 38. Development of linear, ensemble, and nonlinear models for the prediction and interpretation of the biological activity of a set of PDGFR inhibitors.
    Guha R; Jurs PC
    J Chem Inf Comput Sci; 2004; 44(6):2179-89. PubMed ID: 15554688
    [TBL] [Abstract][Full Text] [Related]  

  • 39. How diverse are diversity assessment methods? A comparative analysis and benchmarking of molecular descriptor space.
    Koutsoukas A; Paricharak S; Galloway WR; Spring DR; Ijzerman AP; Glen RC; Marcus D; Bender A
    J Chem Inf Model; 2014 Jan; 54(1):230-42. PubMed ID: 24289493
    [TBL] [Abstract][Full Text] [Related]  

  • 40. Skin permeation rate as a function of chemical structure.
    Katritzky AR; Dobchev DA; Fara DC; Hür E; Tämm K; Kurunczi L; Karelson M; Varnek A; Solov'ev VP
    J Med Chem; 2006 Jun; 49(11):3305-14. PubMed ID: 16722649
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 8.