These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

217 related articles for article (PubMed ID: 27603548)

  • 1. Pre-incubation with cyclosporine A potentiates its inhibitory effects on pitavastatin uptake mediated by recombinantly expressed cynomolgus monkey hepatic organic anion transporting polypeptide.
    Takahashi T; Ohtsuka T; Uno Y; Utoh M; Yamazaki H; Kume T
    Biopharm Drug Dispos; 2016 Nov; 37(8):479-490. PubMed ID: 27603548
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Functional characterization for polymorphic organic anion transporting polypeptides (OATP/SLCO1B1, 1B3, 2B1) of monkeys recombinantly expressed with various OATP probes.
    Takahashi T; Uno Y; Yamazaki H; Kume T
    Biopharm Drug Dispos; 2019 Feb; 40(2):62-69. PubMed ID: 30652318
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Drug-drug interaction between pitavastatin and various drugs via OATP1B1.
    Hirano M; Maeda K; Shitara Y; Sugiyama Y
    Drug Metab Dispos; 2006 Jul; 34(7):1229-36. PubMed ID: 16595711
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Prediction and Quantification of Hepatic Transporter-Mediated Uptake of Pitavastatin Utilizing a Combination of the Relative Activity Factor Approach and Mechanistic Modeling.
    Mitra P; Weinheimer S; Michalewicz M; Taub ME
    Drug Metab Dispos; 2018 Jul; 46(7):953-963. PubMed ID: 29666154
    [TBL] [Abstract][Full Text] [Related]  

  • 5. In Vitro-In Vivo Extrapolation of OATP1B-Mediated Drug-Drug Interactions in Cynomolgus Monkey.
    Ufuk A; Kosa RE; Gao H; Bi YA; Modi S; Gates D; Rodrigues AD; Tremaine LM; Varma MVS; Houston JB; Galetin A
    J Pharmacol Exp Ther; 2018 Jun; 365(3):688-699. PubMed ID: 29643253
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Pitavastatin as an in vivo probe for studying hepatic organic anion transporting polypeptide-mediated drug-drug interactions in cynomolgus monkeys.
    Takahashi T; Ohtsuka T; Yoshikawa T; Tatekawa I; Uno Y; Utoh M; Yamazaki H; Kume T
    Drug Metab Dispos; 2013 Oct; 41(10):1875-82. PubMed ID: 23929936
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Pre-incubation with OATP1B1 and OATP1B3 inhibitors potentiates inhibitory effects in physiologically relevant sandwich-cultured primary human hepatocytes.
    Farasyn T; Pahwa S; Xu C; Yue W
    Eur J Pharm Sci; 2021 Oct; 165():105951. PubMed ID: 34311070
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Simultaneous Assessment of Transporter-Mediated Drug-Drug Interactions Using a Probe Drug Cocktail in Cynomolgus Monkey.
    Kosa RE; Lazzaro S; Bi YA; Tierney B; Gates D; Modi S; Costales C; Rodrigues AD; Tremaine LM; Varma MV
    Drug Metab Dispos; 2018 Aug; 46(8):1179-1189. PubMed ID: 29880631
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Prediction of organic anion-transporting polypeptide 1B1- and 1B3-mediated hepatic uptake of statins based on transporter protein expression and activity data.
    Kunze A; Huwyler J; Camenisch G; Poller B
    Drug Metab Dispos; 2014 Sep; 42(9):1514-21. PubMed ID: 24989890
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Influence of non-steroidal anti-inflammatory drugs on organic anion transporting polypeptide (OATP) 1B1- and OATP1B3-mediated drug transport.
    Kindla J; Müller F; Mieth M; Fromm MF; König J
    Drug Metab Dispos; 2011 Jun; 39(6):1047-53. PubMed ID: 21389119
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Preclinical Mouse Models To Study Human OATP1B1- and OATP1B3-Mediated Drug-Drug Interactions in Vivo.
    Durmus S; Lozano-Mena G; van Esch A; Wagenaar E; van Tellingen O; Schinkel AH
    Mol Pharm; 2015 Dec; 12(12):4259-69. PubMed ID: 26474710
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Dissecting the Contribution of OATP1B1 to Hepatic Uptake of Statins Using the OATP1B1 Selective Inhibitor Estropipate.
    Zhang Y; Panfen E; Fancher M; Sinz M; Marathe P; Shen H
    Mol Pharm; 2019 Jun; 16(6):2342-2353. PubMed ID: 31039308
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Investigation of the impact of substrate selection on in vitro organic anion transporting polypeptide 1B1 inhibition profiles for the prediction of drug-drug interactions.
    Izumi S; Nozaki Y; Maeda K; Komori T; Takenaka O; Kusuhara H; Sugiyama Y
    Drug Metab Dispos; 2015 Feb; 43(2):235-47. PubMed ID: 25414411
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Interaction of digitalis-like compounds with liver uptake transporters NTCP, OATP1B1, and OATP1B3.
    Gozalpour E; Greupink R; Wortelboer HM; Bilos A; Schreurs M; Russel FG; Koenderink JB
    Mol Pharm; 2014 Jun; 11(6):1844-55. PubMed ID: 24754247
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Dehydroepiandrosterone sulfate, a useful endogenous probe for evaluation of drug-drug interaction on hepatic organic anion transporting polypeptide (OATP) in cynomolgus monkeys.
    Watanabe M; Watanabe T; Yabuki M; Tamai I
    Drug Metab Pharmacokinet; 2015 Apr; 30(2):198-204. PubMed ID: 25989893
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Leveraging of Rifampicin-Dosed Cynomolgus Monkeys to Identify Bile Acid 3-O-Sulfate Conjugates as Potential Novel Biomarkers for Organic Anion-Transporting Polypeptides.
    Thakare R; Gao H; Kosa RE; Bi YA; Varma MVS; Cerny MA; Sharma R; Kuhn M; Huang B; Liu Y; Yu A; Walker GS; Niosi M; Tremaine L; Alnouti Y; Rodrigues AD
    Drug Metab Dispos; 2017 Jul; 45(7):721-733. PubMed ID: 28396527
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Downregulation of Organic Anion Transporting Polypeptide (OATP) 1B1 Transport Function by Lysosomotropic Drug Chloroquine: Implication in OATP-Mediated Drug-Drug Interactions.
    Alam K; Pahwa S; Wang X; Zhang P; Ding K; Abuznait AH; Li L; Yue W
    Mol Pharm; 2016 Mar; 13(3):839-51. PubMed ID: 26750564
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Evaluation of rosuvastatin as an organic anion transporting polypeptide (OATP) probe substrate: in vitro transport and in vivo disposition in cynomolgus monkeys.
    Shen H; Su H; Liu T; Yao M; Mintier G; Li L; Fancher RM; Iyer R; Marathe P; Lai Y; Rodrigues AD
    J Pharmacol Exp Ther; 2015 May; 353(2):380-91. PubMed ID: 25740896
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Cynomolgus monkey as a potential model to assess drug interactions involving hepatic organic anion transporting polypeptides: in vitro, in vivo, and in vitro-to-in vivo extrapolation.
    Shen H; Yang Z; Mintier G; Han YH; Chen C; Balimane P; Jemal M; Zhao W; Zhang R; Kallipatti S; Selvam S; Sukrutharaj S; Krishnamurthy P; Marathe P; Rodrigues AD
    J Pharmacol Exp Ther; 2013 Mar; 344(3):673-85. PubMed ID: 23297161
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Predicting Human Clearance of Organic Anion Transporting Polypeptide Substrates Using Cynomolgus Monkey: In Vitro-In Vivo Scaling of Hepatic Uptake Clearance.
    De Bruyn T; Ufuk A; Cantrill C; Kosa RE; Bi YA; Niosi M; Modi S; Rodrigues AD; Tremaine LM; Varma MVS; Galetin A; Houston JB
    Drug Metab Dispos; 2018 Jul; 46(7):989-1000. PubMed ID: 29720472
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.