BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

163 related articles for article (PubMed ID: 27604270)

  • 1. Single-shot multi-reaction monitoring of intact marker conjugates for quantitative profiling of human major microsomal glucuronidations and its utility to screen inhibitors from medicinal herbs.
    Cheng Y; Zhou J; Wang M; Liu Y; Guo B; Chen B
    Anal Bioanal Chem; 2016 Nov; 408(28):8117-8132. PubMed ID: 27604270
    [TBL] [Abstract][Full Text] [Related]  

  • 2. In vitro assay of six UDP-glucuronosyltransferase isoforms in human liver microsomes, using cocktails of probe substrates and liquid chromatography-tandem mass spectrometry.
    Seo KA; Kim HJ; Jeong ES; Abdalla N; Choi CS; Kim DH; Shin JG
    Drug Metab Dispos; 2014 Nov; 42(11):1803-10. PubMed ID: 25122565
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Optimized assays for human UDP-glucuronosyltransferase (UGT) activities: altered alamethicin concentration and utility to screen for UGT inhibitors.
    Walsky RL; Bauman JN; Bourcier K; Giddens G; Lapham K; Negahban A; Ryder TF; Obach RS; Hyland R; Goosen TC
    Drug Metab Dispos; 2012 May; 40(5):1051-65. PubMed ID: 22357286
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Design and optimization of the cocktail assay for rapid assessment of the activity of UGT enzymes in human and rat liver microsomes.
    Chen A; Zhou X; Cheng Y; Tang S; Liu M; Wang X
    Toxicol Lett; 2018 Oct; 295():379-389. PubMed ID: 30036684
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Glucuronidation of the aspirin metabolite salicylic acid by expressed UDP-glucuronosyltransferases and human liver microsomes.
    Kuehl GE; Bigler J; Potter JD; Lampe JW
    Drug Metab Dispos; 2006 Feb; 34(2):199-202. PubMed ID: 16258079
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Optimized methods for targeted peptide-based quantification of human uridine 5'-diphosphate-glucuronosyltransferases in biological specimens using liquid chromatography-tandem mass spectrometry.
    Sato Y; Nagata M; Tetsuka K; Tamura K; Miyashita A; Kawamura A; Usui T
    Drug Metab Dispos; 2014 May; 42(5):885-9. PubMed ID: 24595681
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Identification of the UDP-glucuronosyltransferase isoforms involved in mycophenolic acid phase II metabolism.
    Picard N; Ratanasavanh D; Prémaud A; Le Meur Y; Marquet P
    Drug Metab Dispos; 2005 Jan; 33(1):139-46. PubMed ID: 15470161
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Inhibition screening method of microsomal UGTs using the cocktail approach.
    Gradinaru J; Romand S; Geiser L; Carrupt PA; Spaggiari D; Rudaz S
    Eur J Pharm Sci; 2015 Apr; 71():35-45. PubMed ID: 25684194
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Kinetics of acetaminophen glucuronidation by UDP-glucuronosyltransferases 1A1, 1A6, 1A9 and 2B15. Potential implications in acetaminophen-induced hepatotoxicity.
    Mutlib AE; Goosen TC; Bauman JN; Williams JA; Kulkarni S; Kostrubsky S
    Chem Res Toxicol; 2006 May; 19(5):701-9. PubMed ID: 16696573
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Identification of the human UDP-glucuronosyltransferases involved in the glucuronidation of combretastatin A-4.
    Aprile S; Del Grosso E; Grosa G
    Drug Metab Dispos; 2010 Jul; 38(7):1141-6. PubMed ID: 20375181
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Industrial Approach to Determine the Relative Contribution of Seven Major UGT Isoforms to Hepatic Glucuronidation.
    Busse D; Leandersson S; Amberntsson S; Darnell M; Hilgendorf C
    J Pharm Sci; 2020 Jul; 109(7):2309-2320. PubMed ID: 32294459
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Screening of non-steroidal anti-inflammatory drugs for inhibitory effects on the activities of six UDP-glucuronosyltransferases (UGT1A1, 1A3, 1A4, 1A6, 1A9 and 2B7) using LC-MS/MS.
    Joo J; Kim YW; Wu Z; Shin JH; Lee B; Shon JC; Lee EY; Phuc NM; Liu KH
    Biopharm Drug Dispos; 2015 May; 36(4):258-64. PubMed ID: 25522350
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Simultaneous Screening of Activities of Five Cytochrome P450 and Four Uridine 5'-Diphospho-glucuronosyltransferase Enzymes in Human Liver Microsomes Using Cocktail Incubation and Liquid Chromatography-Tandem Mass Spectrometry.
    Lee B; Ji HK; Lee T; Liu KH
    Drug Metab Dispos; 2015 Jul; 43(7):1137-46. PubMed ID: 25904760
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Identification of human UDP-glucuronosyltransferase isoform(s) responsible for the C-glucuronidation of phenylbutazone.
    Nishiyama T; Kobori T; Arai K; Ogura K; Ohnuma T; Ishii K; Hayashi K; Hiratsuka A
    Arch Biochem Biophys; 2006 Oct; 454(1):72-9. PubMed ID: 16949544
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Glucuronidation of nonsteroidal anti-inflammatory drugs: identifying the enzymes responsible in human liver microsomes.
    Kuehl GE; Lampe JW; Potter JD; Bigler J
    Drug Metab Dispos; 2005 Jul; 33(7):1027-35. PubMed ID: 15843492
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Androgen glucuronides analysis by liquid chromatography tandem-mass spectrometry: could it raise new perspectives in the diagnostic field of hormone-dependent malignancies?
    Kalogera E; Pistos C; Provatopoulou X; Athanaselis S; Spiliopoulou C; Gounaris A
    J Chromatogr B Analyt Technol Biomed Life Sci; 2013 Dec; 940():24-34. PubMed ID: 24140653
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Gossypol exhibits a strong influence towards UDP-glucuronosyltransferase (UGT) 1A1, 1A9 and 2B7-mediated metabolism of xenobiotics and endogenous substances.
    Zhang YS; Yuan J; Fang ZZ; Tu YY; Hu CM; Li G; Wang L; Deng JP; Yao JJ; Li HR
    Molecules; 2012 Apr; 17(5):4896-903. PubMed ID: 22543504
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Hepatic microsomal UDP-glucuronosyltransferase (UGT) activities in the microminipig.
    Higashi E; Ando A; Iwano S; Murayama N; Yamazaki H; Miyamoto Y
    Biopharm Drug Dispos; 2014 Sep; 35(6):313-20. PubMed ID: 24752421
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Predominant contribution of UDP-glucuronosyltransferase 2B7 in the glucuronidation of racemic flurbiprofen in the human liver.
    Mano Y; Usui T; Kamimura H
    Drug Metab Dispos; 2007 Jul; 35(7):1182-7. PubMed ID: 17446261
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Characterizations of Human UDP-Glucuronosyltransferase Enzymes in the Conjugation of p-Cresol.
    Rong Y; Kiang TKL
    Toxicol Sci; 2020 Aug; 176(2):285-296. PubMed ID: 32421801
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.