BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

194 related articles for article (PubMed ID: 27611801)

  • 1. A Novel Malate Dehydrogenase 2 Inhibitor Suppresses Hypoxia-Inducible Factor-1 by Regulating Mitochondrial Respiration.
    Ban HS; Xu X; Jang K; Kim I; Kim BK; Lee K; Won M
    PLoS One; 2016; 11(9):e0162568. PubMed ID: 27611801
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Methyl 3-(3-(4-(2,4,4-Trimethylpentan-2-yl)phenoxy)-propanamido)benzoate as a Novel and Dual Malate Dehydrogenase (MDH) 1/2 Inhibitor Targeting Cancer Metabolism.
    Naik R; Ban HS; Jang K; Kim I; Xu X; Harmalkar D; Shin SA; Kim M; Kim BK; Park J; Ku B; Oh S; Won M; Lee K
    J Med Chem; 2017 Oct; 60(20):8631-8646. PubMed ID: 28991459
    [TBL] [Abstract][Full Text] [Related]  

  • 3. The novel hypoxia-inducible factor-1α inhibitor IDF-11774 regulates cancer metabolism, thereby suppressing tumor growth.
    Ban HS; Kim BK; Lee H; Kim HM; Harmalkar D; Nam M; Park SK; Lee K; Park JT; Kim I; Lee K; Hwang GS; Won M
    Cell Death Dis; 2017 Jun; 8(6):e2843. PubMed ID: 28569777
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Orexin A affects HepG2 human hepatocellular carcinoma cells glucose metabolism via HIF-1α-dependent and -independent mechanism.
    Wan X; Liu Y; Zhao Y; Sun X; Fan D; Guo L
    PLoS One; 2017; 12(9):e0184213. PubMed ID: 28886081
    [TBL] [Abstract][Full Text] [Related]  

  • 5. The disubstituted adamantyl derivative LW1564 inhibits the growth of cancer cells by targeting mitochondrial respiration and reducing hypoxia-inducible factor (HIF)-1α accumulation.
    Kim I; Kim M; Park MK; Naik R; Park JH; Kim BK; Choi Y; Chang KY; Won M; Ban HS; Lee K
    Exp Mol Med; 2020 Nov; 52(11):1845-1856. PubMed ID: 33235318
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Synthesis and structure-activity relationship study of chemical probes as hypoxia induced factor-1α/malate dehydrogenase 2 inhibitors.
    Naik R; Won M; Ban HS; Bhattarai D; Xu X; Eo Y; Hong YS; Singh S; Choi Y; Ahn HC; Lee K
    J Med Chem; 2014 Nov; 57(22):9522-38. PubMed ID: 25356789
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Kamebakaurin inhibits the expression of hypoxia-inducible factor-1α and its target genes to confer antitumor activity.
    Wang KS; Ma J; Mi C; Li J; Lee JJ; Jin X
    Oncol Rep; 2016 Apr; 35(4):2045-52. PubMed ID: 26781327
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Synthesis, biological evaluation and molecular docking studies of indeno [1, 2-c] pyrazol derivatives as inhibitors of mitochondrial malate dehydrogenase 2 (MDH2).
    Ahmadi F; Engel M; Baradarani MM
    Bioorg Chem; 2021 May; 110():104779. PubMed ID: 33689977
    [TBL] [Abstract][Full Text] [Related]  

  • 9. The Apoptotic Effect of HIF-1α Inhibition Combined with Glucose plus Insulin Treatment on Gastric Cancer under Hypoxic Conditions.
    Tanaka T; Kitajima Y; Miyake S; Yanagihara K; Hara H; Nishijima-Matsunobu A; Baba K; Shida M; Wakiyama K; Nakamura J; Noshiro H
    PLoS One; 2015; 10(9):e0137257. PubMed ID: 26339797
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Methylalpinumisoflavone inhibits hypoxia-inducible factor-1 (HIF-1) activation by simultaneously targeting multiple pathways.
    Liu Y; Veena CK; Morgan JB; Mohammed KA; Jekabsons MB; Nagle DG; Zhou YD
    J Biol Chem; 2009 Feb; 284(9):5859-68. PubMed ID: 19091749
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Perillyl alcohol efficiently scavenges activity of cellular ROS and inhibits the translational expression of hypoxia-inducible factor-1α via mTOR/4E-BP1 signaling pathways.
    Ma J; Li J; Wang KS; Mi C; Piao LX; Xu GH; Li X; Lee JJ; Jin X
    Int Immunopharmacol; 2016 Oct; 39():1-9. PubMed ID: 27394002
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Licochalcone A inhibits hypoxia-inducible factor-1α accumulation by suppressing mitochondrial respiration in hypoxic cancer cells.
    Park MK; Ji J; Haam K; Han TH; Lim S; Kang MJ; Lim SS; Ban HS
    Biomed Pharmacother; 2021 Jan; 133():111082. PubMed ID: 33378978
    [TBL] [Abstract][Full Text] [Related]  

  • 13. The novel hypoxic cytotoxin, TX-2098 has antitumor effect in pancreatic cancer; possible mechanism through inhibiting VEGF and hypoxia inducible factor-1α targeted gene expression.
    Miyake K; Nishioka M; Imura S; Batmunkh E; Uto Y; Nagasawa H; Hori H; Shimada M
    Exp Cell Res; 2012 Aug; 318(13):1554-63. PubMed ID: 22472348
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Sestrin2 inhibits hypoxia-inducible factor-1α accumulation via AMPK-mediated prolyl hydroxylase regulation.
    Seo K; Seo S; Ki SH; Shin SM
    Free Radic Biol Med; 2016 Dec; 101():511-523. PubMed ID: 27840318
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Ethyl pyruvate stabilizes hypoxia-inducible factor 1 alpha via stimulation of the TCA cycle.
    Kim SY; Choi JS; Park C; Jeong JW
    Cancer Lett; 2010 Sep; 295(2):236-41. PubMed ID: 20338685
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Hypoxia-independent overexpression of hypoxia-inducible factor 1alpha as an early change in mouse hepatocarcinogenesis.
    Tanaka H; Yamamoto M; Hashimoto N; Miyakoshi M; Tamakawa S; Yoshie M; Tokusashi Y; Yokoyama K; Yaginuma Y; Ogawa K
    Cancer Res; 2006 Dec; 66(23):11263-70. PubMed ID: 17145871
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Magnolol suppresses hypoxia-induced angiogenesis via inhibition of HIF-1α/VEGF signaling pathway in human bladder cancer cells.
    Chen MC; Lee CF; Huang WH; Chou TC
    Biochem Pharmacol; 2013 May; 85(9):1278-87. PubMed ID: 23416116
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Jianpi Jiedu decoction, a traditional Chinese medicine formula, inhibits tumorigenesis, metastasis, and angiogenesis through the mTOR/HIF-1α/VEGF pathway.
    Peng W; Zhang S; Zhang Z; Xu P; Mao D; Huang S; Chen B; Zhang C; Zhang S
    J Ethnopharmacol; 2018 Oct; 224():140-148. PubMed ID: 29852266
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Cyclin-dependent kinase inhibitor, P276-00, inhibits HIF-1α and induces G2/M arrest under hypoxia in prostate cancer cells.
    Manohar SM; Padgaonkar AA; Jalota-Badhwar A; Rao SV; Joshi KS
    Prostate Cancer Prostatic Dis; 2012 Mar; 15(1):15-27. PubMed ID: 22083267
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Vosaroxin induces mitochondrial dysfunction and apoptosis in cervical cancer HeLa cells: Involvement of AMPK/Sirt3/HIF-1 pathway.
    Zhao XL; Yu CZ
    Chem Biol Interact; 2018 Jun; 290():57-63. PubMed ID: 29800573
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.