192 related articles for article (PubMed ID: 27617850)
21. Structural biology of the Bcl-2 family of proteins.
Petros AM; Olejniczak ET; Fesik SW
Biochim Biophys Acta; 2004 Mar; 1644(2-3):83-94. PubMed ID: 14996493
[TBL] [Abstract][Full Text] [Related]
22. Activation of apoptosis in vivo by a hydrocarbon-stapled BH3 helix.
Walensky LD; Kung AL; Escher I; Malia TJ; Barbuto S; Wright RD; Wagner G; Verdine GL; Korsmeyer SJ
Science; 2004 Sep; 305(5689):1466-70. PubMed ID: 15353804
[TBL] [Abstract][Full Text] [Related]
23. A synthetic peptide targeting the BH4 domain of Bcl-2 induces apoptosis in multiple myeloma and follicular lymphoma cells alone or in combination with agents targeting the BH3-binding pocket of Bcl-2.
Lavik AR; Zhong F; Chang MJ; Greenberg E; Choudhary Y; Smith MR; McColl KS; Pink J; Reu FJ; Matsuyama S; Distelhorst CW
Oncotarget; 2015 Sep; 6(29):27388-402. PubMed ID: 26317541
[TBL] [Abstract][Full Text] [Related]
24. Discovery and Characterization of 2,5-Substituted Benzoic Acid Dual Inhibitors of the Anti-apoptotic Mcl-1 and Bfl-1 Proteins.
Kump KJ; Miao L; Mady ASA; Ansari NH; Shrestha UK; Yang Y; Pal M; Liao C; Perdih A; Abulwerdi FA; Chinnaswamy K; Meagher JL; Carlson JM; Khanna M; Stuckey JA; Nikolovska-Coleska Z
J Med Chem; 2020 Mar; 63(5):2489-2510. PubMed ID: 31971799
[TBL] [Abstract][Full Text] [Related]
25. Tertiary Structural Motif Sequence Statistics Enable Facile Prediction and Design of Peptides that Bind Anti-apoptotic Bfl-1 and Mcl-1.
Frappier V; Jenson JM; Zhou J; Grigoryan G; Keating AE
Structure; 2019 Apr; 27(4):606-617.e5. PubMed ID: 30773399
[TBL] [Abstract][Full Text] [Related]
26. Anti-apoptotic Bcl-XL protein in complex with BH3 peptides of pro-apoptotic Bak, Bad, and Bim proteins: comparative molecular dynamics simulations.
Lama D; Sankararamakrishnan R
Proteins; 2008 Nov; 73(2):492-514. PubMed ID: 18452209
[TBL] [Abstract][Full Text] [Related]
27. A stapled BIM peptide overcomes apoptotic resistance in hematologic cancers.
LaBelle JL; Katz SG; Bird GH; Gavathiotis E; Stewart ML; Lawrence C; Fisher JK; Godes M; Pitter K; Kung AL; Walensky LD
J Clin Invest; 2012 Jun; 122(6):2018-31. PubMed ID: 22622039
[TBL] [Abstract][Full Text] [Related]
28. Deciphering the crucial residues involved in heterodimerization of Bak peptide and anti-apoptotic proteins for apoptosis.
Marimuthu P; Singaravelu K
J Biomol Struct Dyn; 2018 May; 36(6):1637-1648. PubMed ID: 28511583
[TBL] [Abstract][Full Text] [Related]
29. Bicyclic Helical Peptides as Dual Inhibitors Selective for Bcl2A1 and Mcl-1 Proteins.
D de Araujo A; Lim J; Wu KC; Xiang Y; Good AC; Skerlj R; Fairlie DP
J Med Chem; 2018 Apr; 61(7):2962-2972. PubMed ID: 29584430
[TBL] [Abstract][Full Text] [Related]
30. N-locking stabilization of covalent helical peptides: Application to Bfl-1 antagonists.
Baggio C; Udompholkul P; Gambini L; Jossart J; Salem AF; Håkansson M; Perry JJP; Pellecchia M
Chem Biol Drug Des; 2020 Apr; 95(4):412-426. PubMed ID: 31898401
[TBL] [Abstract][Full Text] [Related]
31. Targeting of p53 peptide analogues to anti-apoptotic Bcl-2 family proteins as revealed by NMR spectroscopy.
Shin JS; Ha JH; Chi SW
Biochem Biophys Res Commun; 2014 Jan; 443(3):882-7. PubMed ID: 24342622
[TBL] [Abstract][Full Text] [Related]
32. A novel BH3 mimetic efficiently induces apoptosis in melanoma cells through direct binding to anti-apoptotic Bcl-2 family proteins, including phosphorylated Mcl-1.
Liu Y; Xie M; Song T; Sheng H; Yu X; Zhang Z
Pigment Cell Melanoma Res; 2015 Mar; 28(2):161-70. PubMed ID: 25324174
[TBL] [Abstract][Full Text] [Related]
33. Targeting ERK1/2-bim signaling cascades by BH3-mimetic ABT-737 as an alternative therapeutic strategy for oral cancer.
Shin JA; Kim LH; Lee SJ; Jeong JH; Jung JY; Lee HN; Hong IS; Cho SD
Oncotarget; 2015 Nov; 6(34):35667-83. PubMed ID: 26447615
[TBL] [Abstract][Full Text] [Related]
34. Modulation of NOXA and MCL-1 as a strategy for sensitizing melanoma cells to the BH3-mimetic ABT-737.
Lucas KM; Mohana-Kumaran N; Lau D; Zhang XD; Hersey P; Huang DC; Weninger W; Haass NK; Allen JD
Clin Cancer Res; 2012 Feb; 18(3):783-95. PubMed ID: 22173547
[TBL] [Abstract][Full Text] [Related]
35. Induction of apoptosis in prostate carcinoma cells by BH3 peptides which inhibit Bak/Bcl-2 interactions.
Finnegan NM; Curtin JF; Prevost G; Morgan B; Cotter TG
Br J Cancer; 2001 Jul; 85(1):115-21. PubMed ID: 11437412
[TBL] [Abstract][Full Text] [Related]
36. Discovery and optimization of (2-naphthylthio)acetic acid derivative as selective Bfl-1 inhibitor.
Niu P; Xu H; Fan M
Bioorg Med Chem Lett; 2024 Mar; 101():129658. PubMed ID: 38373466
[TBL] [Abstract][Full Text] [Related]
37. Structural basis for the conserved binding mechanism of MDM2-inhibiting peptides and anti-apoptotic Bcl-2 family proteins.
Lee MS; Ha JH; Yoon HS; Lee CK; Chi SW
Biochem Biophys Res Commun; 2014 Feb; 445(1):120-5. PubMed ID: 24491548
[TBL] [Abstract][Full Text] [Related]
38. Iterative optimization yields Mcl-1-targeting stapled peptides with selective cytotoxicity to Mcl-1-dependent cancer cells.
Rezaei Araghi R; Bird GH; Ryan JA; Jenson JM; Godes M; Pritz JR; Grant RA; Letai A; Walensky LD; Keating AE
Proc Natl Acad Sci U S A; 2018 Jan; 115(5):E886-E895. PubMed ID: 29339518
[TBL] [Abstract][Full Text] [Related]
39. Targeted Polymersome Delivery of a Stapled Peptide for Drugging the Tumor Protein p53:BCL-2-Family Axis in Diffuse Large B-Cell Lymphoma.
Schnorenberg MR; Hawley KM; Thomas-Toth AT; Watkins EA; Tian Y; Ting JM; Leak LB; Kucera IM; Raczy MM; Kung AL; Hubbell JA; Tirrell MV; LaBelle JL
ACS Nano; 2023 Dec; 17(23):23374-23390. PubMed ID: 37688780
[TBL] [Abstract][Full Text] [Related]
40. Peptide screening to knockdown Bcl-2's anti-apoptotic activity: implications in cancer treatment.
Raghav PK; Verma YK; Gangenahalli GU
Int J Biol Macromol; 2012 Apr; 50(3):796-814. PubMed ID: 22155216
[TBL] [Abstract][Full Text] [Related]
[Previous] [Next] [New Search]
