BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

412 related articles for article (PubMed ID: 27617904)

  • 1. Fam60A plays a role for production stabilities of recombinant CHO cell lines.
    Ritter A; Nuciforo S; Schulze A; Oertli M; Rauschert T; Voedisch B; Geisse S; Jostock T; Laux H
    Biotechnol Bioeng; 2017 Mar; 114(3):701-704. PubMed ID: 27617904
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Disruption of the gene C12orf35 leads to increased productivities in recombinant CHO cell lines.
    Ritter A; Rauschert T; Oertli M; Piehlmaier D; Mantas P; Kuntzelmann G; Lageyre N; Brannetti B; Voedisch B; Geisse S; Jostock T; Laux H
    Biotechnol Bioeng; 2016 Nov; 113(11):2433-42. PubMed ID: 27183150
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Deletion of a telomeric region on chromosome 8 correlates with higher productivity and stability of CHO cell lines.
    Ritter A; Voedisch B; Wienberg J; Wilms B; Geisse S; Jostock T; Laux H
    Biotechnol Bioeng; 2016 May; 113(5):1084-93. PubMed ID: 26523402
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Mechanisms underlying epigenetic and transcriptional heterogeneity in Chinese hamster ovary (CHO) cell lines.
    Veith N; Ziehr H; MacLeod RA; Reamon-Buettner SM
    BMC Biotechnol; 2016 Jan; 16():6. PubMed ID: 26800878
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Chinese hamster ovary (CHO) host cell engineering to increase sialylation of recombinant therapeutic proteins by modulating sialyltransferase expression.
    Lin N; Mascarenhas J; Sealover NR; George HJ; Brooks J; Kayser KJ; Gau B; Yasa I; Azadi P; Archer-Hartmann S
    Biotechnol Prog; 2015; 31(2):334-46. PubMed ID: 25641927
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Transcriptome study and identification of potential marker genes related to the stable expression of recombinant proteins in CHO clones.
    Jamnikar U; Nikolic P; Belic A; Blas M; Gaser D; Francky A; Laux H; Blejec A; Baebler S; Gruden K
    BMC Biotechnol; 2015 Oct; 15():98. PubMed ID: 26499110
    [TBL] [Abstract][Full Text] [Related]  

  • 7. miRNA engineering of CHO cells facilitates production of difficult-to-express proteins and increases success in cell line development.
    Fischer S; Marquart KF; Pieper LA; Fieder J; Gamer M; Gorr I; Schulz P; Bradl H
    Biotechnol Bioeng; 2017 Jul; 114(7):1495-1510. PubMed ID: 28262952
    [TBL] [Abstract][Full Text] [Related]  

  • 8. A study of monoclonal antibody-producing CHO cell lines: what makes a stable high producer?
    Chusainow J; Yang YS; Yeo JH; Toh PC; Asvadi P; Wong NS; Yap MG
    Biotechnol Bioeng; 2009 Mar; 102(4):1182-96. PubMed ID: 18979540
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Proteomic differences in recombinant CHO cells producing two similar antibody fragments.
    Sommeregger W; Mayrhofer P; Steinfellner W; Reinhart D; Henry M; Clynes M; Meleady P; Kunert R
    Biotechnol Bioeng; 2016 Sep; 113(9):1902-12. PubMed ID: 26913574
    [TBL] [Abstract][Full Text] [Related]  

  • 10. FX knockout CHO hosts can express desired ratios of fucosylated or afucosylated antibodies with high titers and comparable product quality.
    Louie S; Haley B; Marshall B; Heidersbach A; Yim M; Brozynski M; Tang D; Lam C; Petryniak B; Shaw D; Shim J; Miller A; Lowe JB; Snedecor B; Misaghi S
    Biotechnol Bioeng; 2017 Mar; 114(3):632-644. PubMed ID: 27666939
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Chemical inhibition of autophagy: Examining its potential to increase the specific productivity of recombinant CHO cell lines.
    Baek E; Kim CL; Kim MG; Lee JS; Lee GM
    Biotechnol Bioeng; 2016 Sep; 113(9):1953-61. PubMed ID: 26914152
    [TBL] [Abstract][Full Text] [Related]  

  • 12. A framework to quantify karyotype variation associated with CHO cell line instability at a single-cell level.
    Baik JY; Lee KH
    Biotechnol Bioeng; 2017 May; 114(5):1045-1053. PubMed ID: 27922175
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Increased recombinant protein production owing to expanded opportunities for vector integration in high chromosome number Chinese hamster ovary cells.
    Yamano N; Takahashi M; Ali Haghparast SM; Onitsuka M; Kumamoto T; Frank J; Omasa T
    J Biosci Bioeng; 2016 Aug; 122(2):226-31. PubMed ID: 26850366
    [TBL] [Abstract][Full Text] [Related]  

  • 14. A high-yielding CHO transient system: coexpression of genes encoding EBNA-1 and GS enhances transient protein expression.
    Daramola O; Stevenson J; Dean G; Hatton D; Pettman G; Holmes W; Field R
    Biotechnol Prog; 2014; 30(1):132-41. PubMed ID: 24106171
    [TBL] [Abstract][Full Text] [Related]  

  • 15. High levels of histone H3 acetylation at the CMV promoter are predictive of stable expression in Chinese hamster ovary cells.
    Moritz B; Woltering L; Becker PB; Göpfert U
    Biotechnol Prog; 2016 May; 32(3):776-86. PubMed ID: 27073121
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Generation of stable cell lines by site-specific integration of transgenes into engineered Chinese hamster ovary strains using an FLP-FRT system.
    Zhou H; Liu ZG; Sun ZW; Huang Y; Yu WY
    J Biotechnol; 2010 May; 147(2):122-9. PubMed ID: 20371256
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Lengthening of high-yield production levels of monoclonal antibody-producing Chinese hamster ovary cells by downregulation of breast cancer 1.
    Matsuyama R; Yamano N; Kawamura N; Omasa T
    J Biosci Bioeng; 2017 Mar; 123(3):382-389. PubMed ID: 27742176
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Unstable expression of recombinant antibody during long-term culture of CHO cells is accompanied by histone H3 hypoacetylation.
    Paredes V; Park JS; Jeong Y; Yoon J; Baek K
    Biotechnol Lett; 2013 Jul; 35(7):987-93. PubMed ID: 23468139
    [TBL] [Abstract][Full Text] [Related]  

  • 19. A mechanistic understanding of production instability in CHO cell lines expressing recombinant monoclonal antibodies.
    Kim M; O'Callaghan PM; Droms KA; James DC
    Biotechnol Bioeng; 2011 Oct; 108(10):2434-46. PubMed ID: 21538334
    [TBL] [Abstract][Full Text] [Related]  

  • 20. ATF6β-based fine-tuning of the unfolded protein response enhances therapeutic antibody productivity of Chinese hamster ovary cells.
    Pieper LA; Strotbek M; Wenger T; Olayioye MA; Hausser A
    Biotechnol Bioeng; 2017 Jun; 114(6):1310-1318. PubMed ID: 28165157
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 21.