BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

277 related articles for article (PubMed ID: 27618677)

  • 1. Antipsychotic-like Effects of M4 Positive Allosteric Modulators Are Mediated by CB2 Receptor-Dependent Inhibition of Dopamine Release.
    Foster DJ; Wilson JM; Remke DH; Mahmood MS; Uddin MJ; Wess J; Patel S; Marnett LJ; Niswender CM; Jones CK; Xiang Z; Lindsley CW; Rook JM; Conn PJ
    Neuron; 2016 Sep; 91(6):1244-1252. PubMed ID: 27618677
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Muscarinic acetylcholine M
    Liu L; Huang Y; Huang Q; Zhao Z; Yu J; Wang L
    Neuropharmacology; 2017 May; 117():376-386. PubMed ID: 28257887
    [TBL] [Abstract][Full Text] [Related]  

  • 3. The high efficacy of muscarinic M4 receptor in D1 medium spiny neurons reverses striatal hyperdopaminergia.
    Nair AG; Castro LRV; El Khoury M; Gorgievski V; Giros B; Tzavara ET; Hellgren-Kotaleski J; Vincent P
    Neuropharmacology; 2019 Mar; 146():74-83. PubMed ID: 30468798
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Multiple muscarinic acetylcholine receptor subtypes modulate striatal dopamine release, as studied with M1-M5 muscarinic receptor knock-out mice.
    Zhang W; Yamada M; Gomeza J; Basile AS; Wess J
    J Neurosci; 2002 Aug; 22(15):6347-52. PubMed ID: 12151512
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Molecular mechanisms of action and in vivo validation of an M4 muscarinic acetylcholine receptor allosteric modulator with potential antipsychotic properties.
    Leach K; Loiacono RE; Felder CC; McKinzie DL; Mogg A; Shaw DB; Sexton PM; Christopoulos A
    Neuropsychopharmacology; 2010 Mar; 35(4):855-69. PubMed ID: 19940843
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Activation of the mGlu
    Yohn SE; Foster DJ; Covey DP; Moehle MS; Galbraith J; Garcia-Barrantes PM; Cho HP; Bubser M; Blobaum AL; Joffe ME; Cheer JF; Jones CK; Lindsley CW; Conn PJ
    Mol Psychiatry; 2020 Nov; 25(11):2786-2799. PubMed ID: 30116027
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Characterization of the novel positive allosteric modulator, LY2119620, at the muscarinic M(2) and M(4) receptors.
    Croy CH; Schober DA; Xiao H; Quets A; Christopoulos A; Felder CC
    Mol Pharmacol; 2014 Jul; 86(1):106-15. PubMed ID: 24807965
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Modulation of prepulse inhibition through both M(1) and M (4) muscarinic receptors in mice.
    Thomsen M; Wess J; Fulton BS; Fink-Jensen A; Caine SB
    Psychopharmacology (Berl); 2010 Feb; 208(3):401-16. PubMed ID: 20013114
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Antipsychotic drug-like effects of the selective M4 muscarinic acetylcholine receptor positive allosteric modulator VU0152100.
    Byun NE; Grannan M; Bubser M; Barry RL; Thompson A; Rosanelli J; Gowrishankar R; Kelm ND; Damon S; Bridges TM; Melancon BJ; Tarr JC; Brogan JT; Avison MJ; Deutch AY; Wess J; Wood MR; Lindsley CW; Gore JC; Conn PJ; Jones CK
    Neuropsychopharmacology; 2014 Jun; 39(7):1578-93. PubMed ID: 24442096
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Muscarinic receptor M
    Dall C; Weikop P; Dencker D; Molander AC; Wörtwein G; Conn PJ; Fink-Jensen A; Thomsen M
    Drug Alcohol Depend; 2017 Jul; 176():154-161. PubMed ID: 28544993
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Opposing functions of spinal M2, M3, and M4 receptor subtypes in regulation of GABAergic inputs to dorsal horn neurons revealed by muscarinic receptor knockout mice.
    Zhang HM; Chen SR; Matsui M; Gautam D; Wess J; Pan HL
    Mol Pharmacol; 2006 Mar; 69(3):1048-55. PubMed ID: 16365281
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Positive allosteric modulation of M
    Yohn SE; Conn PJ
    Neuropharmacology; 2018 Jul; 136(Pt C):438-448. PubMed ID: 28893562
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Cognitive enhancement and antipsychotic-like activity following repeated dosing with the selective M
    Gould RW; Grannan MD; Gunter BW; Ball J; Bubser M; Bridges TM; Wess J; Wood MW; Brandon NJ; Duggan ME; Niswender CM; Lindsley CW; Conn PJ; Jones CK
    Neuropharmacology; 2018 Jan; 128():492-502. PubMed ID: 28729220
    [TBL] [Abstract][Full Text] [Related]  

  • 14. An allosteric enhancer of M₄ muscarinic acetylcholine receptor function inhibits behavioral and neurochemical effects of cocaine.
    Dencker D; Weikop P; Sørensen G; Woldbye DP; Wörtwein G; Wess J; Fink-Jensen A
    Psychopharmacology (Berl); 2012 Nov; 224(2):277-87. PubMed ID: 22648127
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Generation and pharmacological analysis of M2 and M4 muscarinic receptor knockout mice.
    Gomeza J; Zhang L; Kostenis E; Felder CC; Bymaster FP; Brodkin J; Shannon H; Xia B; Duttaroy A; Deng CX; Wess J
    Life Sci; 2001 Apr; 68(22-23):2457-66. PubMed ID: 11392613
    [TBL] [Abstract][Full Text] [Related]  

  • 16. LY2033298, a positive allosteric modulator at muscarinic M₄ receptors, enhances inhibition by oxotremorine of light-induced phase shifts in hamster circadian activity rhythms.
    Gannon RL; Millan MJ
    Psychopharmacology (Berl); 2012 Nov; 224(2):231-40. PubMed ID: 22610522
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Involvement of a subpopulation of neuronal M4 muscarinic acetylcholine receptors in the antipsychotic-like effects of the M1/M4 preferring muscarinic receptor agonist xanomeline.
    Dencker D; Wörtwein G; Weikop P; Jeon J; Thomsen M; Sager TN; Mørk A; Woldbye DP; Wess J; Fink-Jensen A
    J Neurosci; 2011 Apr; 31(16):5905-8. PubMed ID: 21508215
    [TBL] [Abstract][Full Text] [Related]  

  • 18. State-dependent alterations in sleep/wake architecture elicited by the M4 PAM VU0467154 - Relation to antipsychotic-like drug effects.
    Gould RW; Nedelcovych MT; Gong X; Tsai E; Bubser M; Bridges TM; Wood MR; Duggan ME; Brandon NJ; Dunlop J; Wood MW; Ivarsson M; Noetzel MJ; Daniels JS; Niswender CM; Lindsley CW; Conn PJ; Jones CK
    Neuropharmacology; 2016 Mar; 102():244-53. PubMed ID: 26617071
    [TBL] [Abstract][Full Text] [Related]  

  • 19. RGS4-dependent attenuation of M4 autoreceptor function in striatal cholinergic interneurons following dopamine depletion.
    Ding J; Guzman JN; Tkatch T; Chen S; Goldberg JA; Ebert PJ; Levitt P; Wilson CJ; Hamm HE; Surmeier DJ
    Nat Neurosci; 2006 Jun; 9(6):832-42. PubMed ID: 16699510
    [TBL] [Abstract][Full Text] [Related]  

  • 20. The effects of brucine and alcuronium on the inhibition of [3H]acetylcholine release from rat striatum by muscarinic receptor agonists.
    Dolezal V; Tucek S
    Br J Pharmacol; 1998 Jul; 124(6):1213-8. PubMed ID: 9720793
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 14.