BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

483 related articles for article (PubMed ID: 27621574)

  • 1. Perspectives on the combination of radiotherapy and targeted therapy with DNA repair inhibitors in the treatment of pancreatic cancer.
    Yang SH; Kuo TC; Wu H; Guo JC; Hsu C; Hsu CH; Tien YW; Yeh KH; Cheng AL; Kuo SH
    World J Gastroenterol; 2016 Aug; 22(32):7275-88. PubMed ID: 27621574
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Changes in the response of MCF-7 cells to ionizing radiation after the combination of ATM and DNA-PK inhibition.
    Ćmielová J; Havelek R; Vávrová J; Řezáčová M
    Med Oncol; 2015 May; 32(5):138. PubMed ID: 25801233
    [TBL] [Abstract][Full Text] [Related]  

  • 3. The ATM-Chk2 and ATR-Chk1 pathways in DNA damage signaling and cancer.
    Smith J; Tho LM; Xu N; Gillespie DA
    Adv Cancer Res; 2010; 108():73-112. PubMed ID: 21034966
    [TBL] [Abstract][Full Text] [Related]  

  • 4. ATR/CHK1 inhibitors and cancer therapy.
    Qiu Z; Oleinick NL; Zhang J
    Radiother Oncol; 2018 Mar; 126(3):450-464. PubMed ID: 29054375
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Exploiting replicative stress in gynecological cancers as a therapeutic strategy.
    Ngoi NY; Sundararajan V; Tan DS
    Int J Gynecol Cancer; 2020 Aug; 30(8):1224-1238. PubMed ID: 32571890
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Inhibition of ATR-dependent feedback activation of Chk1 sensitises cancer cells to Chk1 inhibitor monotherapy.
    Massey AJ
    Cancer Lett; 2016 Dec; 383(1):41-52. PubMed ID: 27693461
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Curcumin suppresses multiple DNA damage response pathways and has potency as a sensitizer to PARP inhibitor.
    Ogiwara H; Ui A; Shiotani B; Zou L; Yasui A; Kohno T
    Carcinogenesis; 2013 Nov; 34(11):2486-97. PubMed ID: 23825154
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Common cancer-associated imbalances in the DNA damage response confer sensitivity to single agent ATR inhibition.
    Middleton FK; Patterson MJ; Elstob CJ; Fordham S; Herriott A; Wade MA; McCormick A; Edmondson R; May FE; Allan JM; Pollard JR; Curtin NJ
    Oncotarget; 2015 Oct; 6(32):32396-409. PubMed ID: 26486089
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Inhibition of poly (ADP-ribose) polymerase activates ATM which is required for subsequent homologous recombination repair.
    Bryant HE; Helleday T
    Nucleic Acids Res; 2006; 34(6):1685-91. PubMed ID: 16556909
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Selective radiosensitization of p53 mutant pancreatic cancer cells by combined inhibition of Chk1 and PARP1.
    Vance S; Liu E; Zhao L; Parsels JD; Parsels LA; Brown JL; Maybaum J; Lawrence TS; Morgan MA
    Cell Cycle; 2011 Dec; 10(24):4321-9. PubMed ID: 22134241
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Defining and targeting wild-type BRCA high-grade serous ovarian cancer: DNA repair and cell cycle checkpoints.
    Ivy SP; Kunos CA; Arnaldez FI; Kohn EC
    Expert Opin Investig Drugs; 2019 Sep; 28(9):771-785. PubMed ID: 31449760
    [No Abstract]   [Full Text] [Related]  

  • 12. Targeting the DNA Damage Response and DNA Repair Pathways to Enhance Radiosensitivity in Colorectal Cancer.
    Deng S; Vlatkovic T; Li M; Zhan T; Veldwijk MR; Herskind C
    Cancers (Basel); 2022 Oct; 14(19):. PubMed ID: 36230796
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Therapeutic Implications of p53 Status on Cancer Cell Fate Following Exposure to Ionizing Radiation and the DNA-PK Inhibitor M3814.
    Sun Q; Guo Y; Liu X; Czauderna F; Carr MI; Zenke FT; Blaukat A; Vassilev LT
    Mol Cancer Res; 2019 Dec; 17(12):2457-2468. PubMed ID: 31551253
    [TBL] [Abstract][Full Text] [Related]  

  • 14. DNA damage response signaling pathways and targets for radiotherapy sensitization in cancer.
    Huang RX; Zhou PK
    Signal Transduct Target Ther; 2020 May; 5(1):60. PubMed ID: 32355263
    [TBL] [Abstract][Full Text] [Related]  

  • 15. N-nitroso-N-ethylurea activates DNA damage surveillance pathways and induces transformation in mammalian cells.
    Bodakuntla S; Libi AV; Sural S; Trivedi P; Lahiri M
    BMC Cancer; 2014 Apr; 14():287. PubMed ID: 24758542
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Restored replication fork stabilization, a mechanism of PARP inhibitor resistance, can be overcome by cell cycle checkpoint inhibition.
    Haynes B; Murai J; Lee JM
    Cancer Treat Rev; 2018 Dec; 71():1-7. PubMed ID: 30269007
    [TBL] [Abstract][Full Text] [Related]  

  • 17. ATM regulates ATR chromatin loading in response to DNA double-strand breaks.
    Cuadrado M; Martinez-Pastor B; Murga M; Toledo LI; Gutierrez-Martinez P; Lopez E; Fernandez-Capetillo O
    J Exp Med; 2006 Feb; 203(2):297-303. PubMed ID: 16461339
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Inhibition of hsp90 compromises the DNA damage response to radiation.
    Dote H; Burgan WE; Camphausen K; Tofilon PJ
    Cancer Res; 2006 Sep; 66(18):9211-20. PubMed ID: 16982765
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Imatinib inhibits inactivation of the ATM/ATR signaling pathway and recovery from adriamycin/doxorubicin-induced DNA damage checkpoint arrest.
    Morii M; Fukumoto Y; Kubota S; Yamaguchi N; Nakayama Y; Yamaguchi N
    Cell Biol Int; 2015 Aug; 39(8):923-32. PubMed ID: 25790472
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Aurora-A controls cancer cell radio- and chemoresistance via ATM/Chk2-mediated DNA repair networks.
    Sun H; Wang Y; Wang Z; Meng J; Qi Z; Yang G
    Biochim Biophys Acta; 2014 May; 1843(5):934-44. PubMed ID: 24480460
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 25.