BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

162 related articles for article (PubMed ID: 27626101)

  • 1. A Small-Molecule Screening Platform for the Discovery of Inhibitors of Undecaprenyl Diphosphate Synthase.
    Czarny TL; Brown ED
    ACS Infect Dis; 2016 Jul; 2(7):489-99. PubMed ID: 27626101
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Antagonism screen for inhibitors of bacterial cell wall biogenesis uncovers an inhibitor of undecaprenyl diphosphate synthase.
    Farha MA; Czarny TL; Myers CL; Worrall LJ; French S; Conrady DG; Wang Y; Oldfield E; Strynadka NC; Brown ED
    Proc Natl Acad Sci U S A; 2015 Sep; 112(35):11048-53. PubMed ID: 26283394
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Discovery and Characterization of a Class of Pyrazole Inhibitors of Bacterial Undecaprenyl Pyrophosphate Synthase.
    Concha N; Huang J; Bai X; Benowitz A; Brady P; Grady LC; Kryn LH; Holmes D; Ingraham K; Jin Q; Pothier Kaushansky L; McCloskey L; Messer JA; O'Keefe H; Patel A; Satz AL; Sinnamon RH; Schneck J; Skinner SR; Summerfield J; Taylor A; Taylor JD; Evindar G; Stavenger RA
    J Med Chem; 2016 Aug; 59(15):7299-304. PubMed ID: 27379833
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Bacterial Cell Growth Inhibitors Targeting Undecaprenyl Diphosphate Synthase and Undecaprenyl Diphosphate Phosphatase.
    Wang Y; Desai J; Zhang Y; Malwal SR; Shin CJ; Feng X; Sun H; Liu G; Guo RT; Oldfield E
    ChemMedChem; 2016 Oct; 11(20):2311-2319. PubMed ID: 27578312
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Recent Advances in the Development of Undecaprenyl Pyrophosphate Synthase Inhibitors as Potential Antibacterials.
    Jukic M; Rozman K; Gobec S
    Curr Med Chem; 2016; 23(5):464-82. PubMed ID: 26718796
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Structural Insights into the Inhibition of Undecaprenyl Pyrophosphate Synthase from Gram-Positive Bacteria.
    Workman SD; Day J; Farha MA; El Zahed SS; Bon C; Brown ED; Organ MG; Strynadka NCJ
    J Med Chem; 2021 Sep; 64(18):13540-13550. PubMed ID: 34473495
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Undecaprenyl diphosphate synthase inhibitors: antibacterial drug leads.
    Sinko W; Wang Y; Zhu W; Zhang Y; Feixas F; Cox CL; Mitchell DA; Oldfield E; McCammon JA
    J Med Chem; 2014 Jul; 57(13):5693-701. PubMed ID: 24827744
    [TBL] [Abstract][Full Text] [Related]  

  • 8. A Defective Undecaprenyl Pyrophosphate Synthase Induces Growth and Morphological Defects That Are Suppressed by Mutations in the Isoprenoid Pathway of Escherichia coli.
    MacCain WJ; Kannan S; Jameel DZ; Troutman JM; Young KD
    J Bacteriol; 2018 Sep; 200(18):. PubMed ID: 29986944
    [TBL] [Abstract][Full Text] [Related]  

  • 9. The effect of triton concentration on the activity of undecaprenyl pyrophosphate synthase inhibitors.
    Li H; Huang J; Jiang X; Seefeld M; McQueney M; Macarron R
    J Biomol Screen; 2003 Dec; 8(6):712-5. PubMed ID: 14711397
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Undecaprenyl diphosphate synthase, a cis-prenyltransferase synthesizing lipid carrier for bacterial cell wall biosynthesis.
    Teng KH; Liang PH
    Mol Membr Biol; 2012 Nov; 29(7):267-73. PubMed ID: 22471620
    [TBL] [Abstract][Full Text] [Related]  

  • 11. UDP-N-acetylglucosamine enolpyruvyl transferase as a potential target for antibacterial chemotherapy: recent developments.
    Gautam A; Rishi P; Tewari R
    Appl Microbiol Biotechnol; 2011 Oct; 92(2):211-25. PubMed ID: 21822642
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Antibacterial drug leads: DNA and enzyme multitargeting.
    Zhu W; Wang Y; Li K; Gao J; Huang CH; Chen CC; Ko TP; Zhang Y; Guo RT; Oldfield E
    J Med Chem; 2015 Feb; 58(3):1215-27. PubMed ID: 25574764
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Discovery and structural characterization of an allosteric inhibitor of bacterial cis-prenyltransferase.
    Danley DE; Baima ET; Mansour M; Fennell KF; Chrunyk BA; Mueller JP; Liu S; Qiu X
    Protein Sci; 2015 Jan; 24(1):20-6. PubMed ID: 25287857
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Species differences in alternative substrate utilization by the antibacterial target undecaprenyl pyrophosphate synthase.
    Dodbele S; Martinez CD; Troutman JM
    Biochemistry; 2014 Aug; 53(30):5042-50. PubMed ID: 25020247
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Anti-infectious agents against MRSA.
    Koyama N; Inokoshi J; Tomoda H
    Molecules; 2012 Dec; 18(1):204-24. PubMed ID: 23262449
    [TBL] [Abstract][Full Text] [Related]  

  • 16. A synthetic lethal approach for compound and target identification in Staphylococcus aureus.
    Pasquina L; Santa Maria JP; McKay Wood B; Moussa SH; Matano LM; Santiago M; Martin SE; Lee W; Meredith TC; Walker S
    Nat Chem Biol; 2016 Jan; 12(1):40-5. PubMed ID: 26619249
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Isoprenoid Biosynthesis Inhibitors Targeting Bacterial Cell Growth.
    Desai J; Wang Y; Wang K; Malwal SR; Oldfield E
    ChemMedChem; 2016 Oct; 11(19):2205-2215. PubMed ID: 27571880
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Design and structure-activity relationships of potent and selective inhibitors of undecaprenyl pyrophosphate synthase (UPPS): tetramic, tetronic acids and dihydropyridin-2-ones.
    Peukert S; Sun Y; Zhang R; Hurley B; Sabio M; Shen X; Gray C; Dzink-Fox J; Tao J; Cebula R; Wattanasin S
    Bioorg Med Chem Lett; 2008 Mar; 18(6):1840-4. PubMed ID: 18295483
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Structures, mechanisms and inhibitors of undecaprenyl diphosphate synthase: a cis-prenyltransferase for bacterial peptidoglycan biosynthesis.
    Teng KH; Liang PH
    Bioorg Chem; 2012 Aug; 43():51-7. PubMed ID: 21993493
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Identification and characterization of novel small molecule inhibitors of the acetyltransferase activity of Escherichia coli N-acetylglucosamine-1-phosphate-uridyltransferase/glucosamine-1-phosphate-acetyltransferase (GlmU).
    Sharma R; Rani C; Mehra R; Nargotra A; Chib R; Rajput VS; Kumar S; Singh S; Sharma PR; Khan IA
    Appl Microbiol Biotechnol; 2016 Apr; 100(7):3071-85. PubMed ID: 26563552
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.